{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=115",
    "query": {
      "condition": "Pathophysiology",
      "page": 115
    },
    "page_size": 10
  },
  "pagination": {
    "page": 115,
    "page_size": 10,
    "total_count": 3983,
    "total_pages": 399,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=116&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=114&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-11T14:56:36.803Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00291174",
      "title": "Measuring Electrical Resistance of Different Tissues on the Outer Surface of the Heart",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiomyopathies",
        "Ventricular Dysfunction",
        "Myocardial Infarction",
        "Arrhythmia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 8,
      "start_date": "2006-04",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2016-08-16",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00291174"
    },
    {
      "nct_id": "NCT07169578",
      "title": "A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Alzheimers Disease"
      ],
      "interventions": [
        {
          "name": "Trontinemab",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Hoffmann-La Roche",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 1101,
      "start_date": "2025-09-17",
      "completion_date": "2028-02-16",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 35,
      "location_summary": "Birmingham, Alabama • Sun City, Arizona • Irvine, California + 31 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07169578"
    },
    {
      "nct_id": "NCT01067326",
      "title": "The Effect of Tekturna on Endothelial Function and Endothelial Progenitor Cells in Patients With Early Atherosclerosis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Aliskiren",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2010-02",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2013-02-13",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01067326"
    },
    {
      "nct_id": "NCT02949115",
      "title": "Effects of Red Beetroot Juice on High-Fat Meal-Induced Endothelial Dysfunction and Cardiometabolic Disturbances",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Overweight",
        "Obesity",
        "Aging",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "70 mL red beetroot juice",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "70 mL red beetroot juice without nitrate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "70 mL placebo drink plus potassium nitrate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "70 mL placebo drink",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Colorado State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 15,
      "start_date": "2016-11",
      "completion_date": "2019-06",
      "has_results": false,
      "last_update_posted_date": "2018-11-13",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 1,
      "location_summary": "Fort Collins, Colorado",
      "locations": [
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02949115"
    },
    {
      "nct_id": "NCT00651950",
      "title": "Bench Study of Transcutaneous Hydrocephalic Shunt Flow Sensor Alignment Accuracy and Repeatability",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hydrocephalus"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Transonic Systems Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2009-03",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2012-06-05",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00651950"
    },
    {
      "nct_id": "NCT01822535",
      "title": "Body Temperature in Persons With Tetraplegia When Exposed to Cold",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tetraplegia",
        "Hypothermia",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Midodrine hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "James J. Peters Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "68 Years",
        "sex": "ALL",
        "summary": "18 Years to 68 Years"
      },
      "enrollment_count": 30,
      "start_date": "2011-07",
      "completion_date": "2015-10",
      "has_results": true,
      "last_update_posted_date": "2016-03-04",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01822535"
    },
    {
      "nct_id": "NCT02276417",
      "title": "PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Blood Collection",
          "type": "OTHER"
        },
        {
          "name": "Urine collection",
          "type": "OTHER"
        },
        {
          "name": "Bioimpedance Analysis",
          "type": "OTHER"
        },
        {
          "name": "Cognitive Function Tests",
          "type": "OTHER"
        },
        {
          "name": "Quality-of-life Questionnaires",
          "type": "OTHER"
        },
        {
          "name": "Physical Function Tests",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 668,
      "start_date": "2015-01",
      "completion_date": "2027-07-24",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02276417"
    },
    {
      "nct_id": "NCT00121485",
      "title": "Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Destination Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure, Congestive",
        "Ventricular Dysfunction",
        "Cardiomyopathies"
      ],
      "interventions": [
        {
          "name": "Left Ventricular Assist System (LVAS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2005-02",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2022-06-27",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 45,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • San Diego, California + 37 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00121485"
    },
    {
      "nct_id": "NCT03953768",
      "title": "VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autoimmune Diseases",
        "Epilepsy",
        "Autonomic Dysfunction",
        "Inflammatory Bowel Diseases"
      ],
      "interventions": [
        {
          "name": "Vagal nerve stimulation (VNS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "0 Years to 60 Years"
      },
      "enrollment_count": 30,
      "start_date": "2021-04-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-25",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 4,
      "location_summary": "Louisville, Kentucky • Houston, Texas • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03953768"
    },
    {
      "nct_id": "NCT07390591",
      "title": "Patient and Caregiver Perspectives on Intravesical Instillations for Urinary Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Cord Injuries",
        "Neurogenic Lower Urinary Tract Dysfunction",
        "Neurogenic Bladder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-06-19",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-11-11T14:56:36.803Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07390591"
    }
  ]
}