{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=9",
    "query": {
      "condition": "Pathophysiology",
      "page": 9
    },
    "page_size": 10
  },
  "pagination": {
    "page": 9,
    "page_size": 10,
    "total_count": 3978,
    "total_pages": 398,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=10&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=8&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-08T05:36:37.243Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01511042",
      "title": "Vascular Dysfunction in Diabetes: Genes and Hormones",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Para-aminohippuric Acid",
          "type": "DRUG"
        },
        {
          "name": "Angiotensin II",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 100,
      "start_date": "1999-12",
      "completion_date": "2020-06",
      "has_results": false,
      "last_update_posted_date": "2022-11-09",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01511042"
    },
    {
      "nct_id": "NCT01615666",
      "title": "A Composite MR Neuroimaging Marker for Alzheimer's Disease",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease",
        "Mild Cognitive Impairment",
        "Frontotemporal Dementia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-03",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-01-14",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01615666"
    },
    {
      "nct_id": "NCT04239079",
      "title": "Autoimmune Features of Neurodegenerative Disorders",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson Disease",
        "Alzheimer Disease",
        "Mild Cognitive Impairment"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "55 Years to 90 Years"
      },
      "enrollment_count": 120,
      "start_date": "2019-05-01",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-08-04",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04239079"
    },
    {
      "nct_id": "NCT03492541",
      "title": "Study of Efficacy and Tolerability of SYSTANE Complete in Patients With Dry Eye Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "Propylene glycol-based eye drops",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 134,
      "start_date": "2018-07-18",
      "completion_date": "2019-05-14",
      "has_results": false,
      "last_update_posted_date": "2019-06-12",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 3,
      "location_summary": "Kansas City, Missouri • Norfolk, Virginia",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03492541"
    },
    {
      "nct_id": "NCT05235113",
      "title": "Remote Game-based Exercise Program for Cognitive and Motor Function Improvement",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Dementia",
        "Cognitive Impairment",
        "Memory Loss"
      ],
      "interventions": [
        {
          "name": "Tele-Exergame Platform",
          "type": "DEVICE"
        },
        {
          "name": "No Tele-Exergame Platform",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2023-11-03",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Houston, Texas",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05235113"
    },
    {
      "nct_id": "NCT07077213",
      "title": "18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) in Tuberculosis Patients",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tuberculosis, Pulmonary"
      ],
      "interventions": [
        {
          "name": "18F-FAPI-74",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2026-03-12",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07077213"
    },
    {
      "nct_id": "NCT06950060",
      "title": "AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke, Chronic",
        "Aging",
        "Cognitive Decline",
        "Motor Dysfunction",
        "Neuroplasticity"
      ],
      "interventions": [
        {
          "name": "High intensity cycling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-intensity cycling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health education session",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Moderate Intensity Aerobic Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 48,
      "start_date": "2026-07-15",
      "completion_date": "2030-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06950060"
    },
    {
      "nct_id": "NCT04400435",
      "title": "Detection of Heart Conditions With Single Lead ECG Using Artificial Intelligence",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Left Ventricular Dysfunction"
      ],
      "interventions": [
        {
          "name": "Use of Eko DUO electronic stethoscope",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Eko Devices, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1258,
      "start_date": "2020-07-15",
      "completion_date": "2022-04-29",
      "has_results": false,
      "last_update_posted_date": "2022-12-09",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 3,
      "location_summary": "Los Alamitos, California • Washington D.C., District of Columbia • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Los Alamitos",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04400435"
    },
    {
      "nct_id": "NCT05770518",
      "title": "Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Paradoxical Vocal Fold Motion",
        "Vocal Cord Dysfunction"
      ],
      "interventions": [
        {
          "name": "Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Laryngeal control therapy (LCT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2023-03-07",
      "completion_date": "2024-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05770518"
    },
    {
      "nct_id": "NCT02695953",
      "title": "Neurobiology of Posttraumatic Stress Disorder Dysfunction and Recovery Following Cognitive Processing Therapy",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Milissa Kaufman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 130,
      "start_date": "2016-03",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-11-08T05:36:37.243Z",
      "location_count": 1,
      "location_summary": "Belmont, Massachusetts",
      "locations": [
        {
          "city": "Belmont",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02695953"
    }
  ]
}