{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pediatric+Autoimmune+Neuropsychiatric+Disorder+Associated+With+Streptococcal+Infection",
    "query": {
      "condition": "Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pediatric+Autoimmune+Neuropsychiatric+Disorder+Associated+With+Streptococcal+Infection&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T10:06:03.249Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04508530",
      "title": "Phase III Study To Compare The Effect of Panzyga Versus Placebo in Patients With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS/PANDAS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pediatric Acute-Onset Neuropsychiatric Syndrome"
      ],
      "interventions": [
        {
          "name": "Panzyga",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Octapharma",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 71,
      "start_date": "2021-06-30",
      "completion_date": "2024-10-30",
      "has_results": true,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 7,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Los Angeles, California + 4 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Centennial",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04508530"
    },
    {
      "nct_id": "NCT06368726",
      "title": "Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Attention",
        "Visual Perceptual Weakness",
        "Social Behavior",
        "Fluency Disorder",
        "EEG With Periodic Abnormalities"
      ],
      "interventions": [
        {
          "name": "tDCS or Transcranial Direct Current Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Risperidone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Spanish Foundation for Neurometrics Development",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "6 Years to 11 Years"
      },
      "enrollment_count": 180,
      "start_date": "2024-04-01",
      "completion_date": "2026-06-02",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06368726"
    },
    {
      "nct_id": "NCT04382716",
      "title": "Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): Clinical Characterization and Prospective Course",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PANS",
        "PANDAS"
      ],
      "interventions": [
        {
          "name": "No intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "4 Years to 16 Years"
      },
      "enrollment_count": 22,
      "start_date": "2018-05-02",
      "completion_date": "2019-08-15",
      "has_results": false,
      "last_update_posted_date": "2020-05-11",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04382716"
    },
    {
      "nct_id": "NCT04015596",
      "title": "Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "PANDAS",
        "Anxiety Disorder",
        "Autoimmune Diseases",
        "Obsessive-Compulsive Disorder"
      ],
      "interventions": [
        {
          "name": "Naproxen Sodium",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "6 Years to 15 Years"
      },
      "enrollment_count": 2,
      "start_date": "2020-10-20",
      "completion_date": "2025-04-30",
      "has_results": true,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04015596"
    },
    {
      "nct_id": "NCT00754897",
      "title": "Feasibility Study for PANDAS",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Inguinal Hernia",
        "Developmental Delay Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Years",
        "sex": "ALL",
        "summary": "Up to 3 Years"
      },
      "enrollment_count": 72,
      "start_date": "2008-11",
      "completion_date": "2009-07",
      "has_results": false,
      "last_update_posted_date": "2009-09-16",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00754897"
    },
    {
      "nct_id": "NCT01617083",
      "title": "Antibiotic Treatment Trial for the PANDAS/PANS Phenotype",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "PANS",
        "PANDAS",
        "Obsessive Compulsive Disorder (OCD)"
      ],
      "interventions": [
        {
          "name": "Azithromycin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "4 Years to 14 Years"
      },
      "enrollment_count": 47,
      "start_date": "2012-05",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2018-04-10",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 1,
      "location_summary": "St. Petersburg, Florida",
      "locations": [
        {
          "city": "St. Petersburg",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01617083"
    },
    {
      "nct_id": "NCT00001658",
      "title": "Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Autoimmune Disease",
        "Mental Disorder",
        "Obsessive Compulsive Disorder",
        "Streptococcal Infection",
        "Tic Disorder"
      ],
      "interventions": [
        {
          "name": "Amoxicillin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 30,
      "start_date": "1997-07",
      "completion_date": "2001-06",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001658"
    },
    {
      "nct_id": "NCT01281969",
      "title": "Intravenous Immunoglobulin for PANDAS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obsessive-Compulsive Disorder",
        "Children",
        "Anxiety Disorder",
        "Autoimmune Disease",
        "PANDAS"
      ],
      "interventions": [
        {
          "name": "Gamunex Intravenous Immunoglobulin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "4 Years to 13 Years"
      },
      "enrollment_count": 48,
      "start_date": "2011-01",
      "completion_date": "2018-08-13",
      "has_results": true,
      "last_update_posted_date": "2020-03-17",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01281969"
    },
    {
      "nct_id": "NCT06811935",
      "title": "PEDI Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcus Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PANS",
        "PANDAS"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-02-17",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 2,
      "location_summary": "Lebanon, New Hampshire • Madison, Wisconsin",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06811935"
    },
    {
      "nct_id": "NCT03348618",
      "title": "A Study to Evaluate the Benefit of Octagam 5%® in Subjects With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pediatric Acute-Onset Neuropsychiatric Syndrome",
        "Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections"
      ],
      "interventions": [
        {
          "name": "IVIG",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "IMMUNOe Research Centers",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "4 Years to 16 Years"
      },
      "enrollment_count": 21,
      "start_date": "2017-11-24",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2019-11-19",
      "last_synced_at": "2026-06-26T10:06:03.249Z",
      "location_count": 3,
      "location_summary": "Centennial, Colorado • Papillion, Nebraska • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Centennial",
          "state": "Colorado"
        },
        {
          "city": "Papillion",
          "state": "Nebraska"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03348618"
    }
  ]
}