{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pediatric+Pulmonary+Hypertension&page=2", "query": { "condition": "Pediatric Pulmonary Hypertension", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pediatric+Pulmonary+Hypertension&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-07-23T08:08:48.335Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01484431", "title": "A Pharmacokinetics Study for Pediatric Participants With Pulmonary Arterial Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "Tadalafil- Tablet or Oral suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Months to 17 Years" }, "enrollment_count": 20, "start_date": "2012-07-17", "completion_date": "2019-04-03", "has_results": true, "last_update_posted_date": "2019-10-09", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 5, "location_summary": "Aurora, Colorado • Atlanta, Georgia • Indianapolis, Indiana + 2 more", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01484431" }, { "nct_id": "NCT01072643", "title": "Sedation With Dexmedetomidine During Cardiac Catheterization", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Pulmonary Hypertension" ], "interventions": [ { "name": "Dexmedetomidine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aruna Nathan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "8 Years to 21 Years" }, "enrollment_count": 4, "start_date": "2010-03", "completion_date": "2013-04", "has_results": true, "last_update_posted_date": "2019-04-16", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01072643" }, { "nct_id": "NCT02610660", "title": "Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hypertension, Pulmonary" ], "interventions": [], "intervention_types": [], "sponsor": "Association for Pediatric Pulmonary Hypertension", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Months", "maximum_age": "18 Years", "sex": "ALL", "summary": "3 Months to 18 Years" }, "enrollment_count": 388, "start_date": "2015-08", "completion_date": "2022-12-31", "has_results": false, "last_update_posted_date": "2023-04-13", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 13, "location_summary": "Palo Alto, California • Aurora, Colorado • Washington D.C., District of Columbia + 10 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02610660" }, { "nct_id": "NCT01342952", "title": "Long-term Ambrisentan Extension Study for Pediatric Patients Who Participated in AMB112529", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension, Pulmonary" ], "interventions": [ { "name": "Ambrisentan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "8 Years to 18 Years" }, "enrollment_count": 38, "start_date": "2011-06-21", "completion_date": "2022-06-09", "has_results": true, "last_update_posted_date": "2022-12-30", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 4, "location_summary": "Aurora, Colorado • Boston, Massachusetts • Ann Arbor, Michigan + 1 more", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01342952" }, { "nct_id": "NCT05169411", "title": "Preserving Kidney Function in Children With Chronic Kidney Disease", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chronic Kidney Disease Stage 2", "Chronic Kidney Disease Stage 3", "Pediatric Kidney Disease" ], "interventions": [ { "name": "Blood pressure", "type": "DIAGNOSTIC_TEST" }, { "name": "Urine protein", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "17 Years", "sex": "ALL", "summary": "1 Year to 17 Years" }, "enrollment_count": 20240, "start_date": "2023-09-22", "completion_date": "2024-07-31", "has_results": false, "last_update_posted_date": "2024-08-16", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05169411" }, { "nct_id": "NCT00718185", "title": "Pharmacokinetics and Pharmacdynamics of Sildenafil", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pulmonary Hypertension" ], "interventions": [ { "name": "Obtain blood specimens", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "28 Days", "maximum_age": null, "sex": "ALL", "summary": "28 Days and older" }, "enrollment_count": 9, "start_date": "2008-05", "completion_date": "2010-02", "has_results": false, "last_update_posted_date": "2015-03-12", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00718185" }, { "nct_id": "NCT02249923", "title": "Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pulmonary Vascular Disease", "Pulmonary Arterial Hypertension" ], "interventions": [], "intervention_types": [], "sponsor": "New York Medical College", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "21 Years", "sex": "ALL", "summary": "1 Day to 21 Years" }, "enrollment_count": 2500, "start_date": "2014-10", "completion_date": "2031-12", "has_results": false, "last_update_posted_date": "2025-03-13", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 13, "location_summary": "Palo Alto, California • San Francisco, California • Aurora, Colorado + 9 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "St. Petersburg", "state": "Florida" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02249923" }, { "nct_id": "NCT04278404", "title": "Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Coronavirus Infection (COVID-19)", "Pulmonary Arterial Hypertension", "Urinary Tract Infections in Children", "Hypertension", "Pain", "Hyperphosphatemia", "Primary Hyperaldosteronism", "Edema", "Hypokalemia", "Heart Failure", "Hemophilia", "Menorrhagia", "Insomnia", "Pneumonia", "Skin Infection", "Arrythmia", "Asthma in Children", "Bronchopulmonary Dysplasia", "Adrenal Insufficiency", "Fibrinolysis; Hemorrhage", "Attention Deficit Hyperactivity Disorder", "Multisystem Inflammatory Syndrome in Children (MIS-C)", "Kawasaki Disease", "Coagulation Disorder", "Down Syndrome" ], "interventions": [ { "name": "The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "0 Years", "maximum_age": "20 Years", "sex": "ALL", "summary": "0 Years to 20 Years" }, "enrollment_count": 5000, "start_date": "2020-03-05", "completion_date": "2027-07", "has_results": false, "last_update_posted_date": "2026-07-15", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 48, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 40 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04278404" }, { "nct_id": "NCT04489251", "title": "Assessment of the TGF-beta Pathway and Micro-RNA in Pediatric Pulmonary Arterial Hypertension", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "Protein Elisa analysis, microRNA analysis, whole exome sequencing", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "2 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "2 Years to 17 Years" }, "enrollment_count": 40, "start_date": "2020-07-01", "completion_date": "2023-01-01", "has_results": false, "last_update_posted_date": "2021-11-22", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04489251" }, { "nct_id": "NCT02276872", "title": "Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PAH" ], "interventions": [ { "name": "oral treprostinil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "United Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Years to 17 Years" }, "enrollment_count": 32, "start_date": "2014-12-18", "completion_date": "2017-07-20", "has_results": true, "last_update_posted_date": "2025-03-30", "last_synced_at": "2026-07-23T08:08:48.335Z", "location_count": 9, "location_summary": "Palo Alto, California • San Francisco, California • Aurora, Colorado + 6 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02276872" } ] }