{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perforation+Bowel&page=2",
    "query": {
      "condition": "Perforation Bowel",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perforation+Bowel&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T22:35:06.194Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00879294",
      "title": "The Effect of Gum Chewing on Postoperative Ileus",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "Motion sickness wristband",
          "type": "DEVICE"
        },
        {
          "name": "Chewing Gum",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-11-06",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00879294"
    },
    {
      "nct_id": "NCT01674478",
      "title": "Early Supplementation of Enteral Microlipid With and Without Fish Oil in Premature Infants With Enterostomies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prematurity",
        "Intestine Perforation",
        "Necrotizing Enterocolitis (NEC)",
        "Short Bowel Syndrome (SBS)"
      ],
      "interventions": [
        {
          "name": "Microlipid with fish oil",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Microlipid",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "2 Months",
        "sex": "ALL",
        "summary": "1 Day to 2 Months"
      },
      "enrollment_count": 18,
      "start_date": "2012-10",
      "completion_date": "2015-03-17",
      "has_results": true,
      "last_update_posted_date": "2018-12-04",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01674478"
    },
    {
      "nct_id": "NCT06705842",
      "title": "APPI-Cost Trial for Perforated Appendicitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "PVI",
          "type": "DRUG"
        },
        {
          "name": "Usual Care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 346,
      "start_date": "2025-04-07",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-11",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06705842"
    },
    {
      "nct_id": "NCT01041079",
      "title": "Chronic Marginal Ulcers After Gastric Bypass",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Marginal Ulcer",
        "Chronic Ulcer Disease",
        "Persistent Ulcer Disease",
        "Recurrent Ulcer Disease",
        "Late Morbidity After Gastric Bypass"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2008-12",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-01-01",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Fresno, California",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01041079"
    },
    {
      "nct_id": "NCT00835458",
      "title": "Endoscopic Treatment of Intestinal Fistulas and Perforations",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastric Fistula"
      ],
      "interventions": [
        {
          "name": "gastro-gastric fistula closure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Legacy Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 5,
      "start_date": "2009-02",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2009-02-11",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00835458"
    },
    {
      "nct_id": "NCT06948071",
      "title": "Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Appendicitis Acute",
        "Appendicitis Perforated",
        "Appendicitis With Perforation",
        "Appendicitis Suppurative",
        "Appendicitis Gangrenous"
      ],
      "interventions": [
        {
          "name": "Discharge on oral antibiotics",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-04-21",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-04-29",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06948071"
    },
    {
      "nct_id": "NCT01303653",
      "title": "Endoscopic Treatment of Intestinal Fistulas and Perforations",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gastrointestinal Fistula",
        "Gastrointestinal Perforation"
      ],
      "interventions": [
        {
          "name": "endoscopic closure of gastrointestinal fistulas and perforations",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Oregon Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 25,
      "start_date": "2010-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2011-02-28",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01303653"
    },
    {
      "nct_id": "NCT00557921",
      "title": "Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Coronary Syndrome",
        "Myocardial Infarction",
        "Coronary Artery Disease",
        "Percutaneous Coronary Intervention"
      ],
      "interventions": [
        {
          "name": "CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin",
          "type": "DRUG"
        },
        {
          "name": "Plavix (clopidogrel 75 mg) and aspirin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cogentus Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 5000,
      "start_date": "2007-12",
      "completion_date": "2009-11",
      "has_results": false,
      "last_update_posted_date": "2009-01-28",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 247,
      "location_summary": "Alexander City, Alabama • Birmingham, Alabama • Geneva, Alabama + 205 more",
      "locations": [
        {
          "city": "Alexander City",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Geneva",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00557921"
    },
    {
      "nct_id": "NCT02784821",
      "title": "Antibiotic \"Dysbiosis\" in Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Enterocolitis, Necrotizing",
        "Bacteremia",
        "Bronchopulmonary Dysplasia",
        "Intraventricular Hemorrhage",
        "Periventricular Leukomalacia",
        "Chronic Lung Disease",
        "Ileal Perforation"
      ],
      "interventions": [
        {
          "name": "Antibiotic",
          "type": "DRUG"
        },
        {
          "name": "Gastric fluid",
          "type": "OTHER"
        },
        {
          "name": "Breast milk",
          "type": "OTHER"
        },
        {
          "name": "Stool samples",
          "type": "OTHER"
        },
        {
          "name": "Antibiotics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "33 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 33 Weeks"
      },
      "enrollment_count": 98,
      "start_date": "2017-01-16",
      "completion_date": "2019-09-11",
      "has_results": true,
      "last_update_posted_date": "2024-06-05",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02784821"
    },
    {
      "nct_id": "NCT00540189",
      "title": "Initial Versus Delayed Operation for Treatment of Complicated Appendicitis In Children",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "Initial appendectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Interval appendectomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Years to 17 Years"
      },
      "enrollment_count": 23,
      "start_date": "2008-05",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2016-12-19",
      "last_synced_at": "2026-06-10T22:35:06.194Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00540189"
    }
  ]
}