{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perfusion+Pressures",
    "query": {
      "condition": "Perfusion Pressures"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 36,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perfusion+Pressures&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T14:21:36.241Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00176722",
      "title": "Intraocular Pressure During Prone Spinal Surgery",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spine Surgery",
        "Vision Impairment"
      ],
      "interventions": [
        {
          "name": "table tilt",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Medicine and Dentistry of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 7,
      "start_date": "2006-06",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2015-04-24",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 2,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        },
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00176722"
    },
    {
      "nct_id": "NCT01117883",
      "title": "Sternal Wall Pressure in the Cath Lab",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perfusion Pressures",
        "Central Venous Pressure",
        "Cardiac Output",
        "CPR",
        "Cardiac Arrest"
      ],
      "interventions": [
        {
          "name": "Application of two different sternal weights",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "7 Years",
        "sex": "ALL",
        "summary": "6 Months to 7 Years"
      },
      "enrollment_count": 20,
      "start_date": "2010-04",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2011-07-14",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01117883"
    },
    {
      "nct_id": "NCT06512935",
      "title": "Ventilator Pressure and Optimization of Compliance and Hemodynamics",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Pulmonary Hypertension Due to Lung Diseases and Hypoxia",
        "Extreme Prematurity",
        "Ventilator Lung; Newborn",
        "Ventilation Perfusion Mismatch"
      ],
      "interventions": [
        {
          "name": "Increase in the PEEP followed by decrease in the PEEP",
          "type": "OTHER"
        },
        {
          "name": "Decrease in the PEEP followed by increase in the PEEP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "7 Days to 30 Days"
      },
      "enrollment_count": 24,
      "start_date": "2026-08-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06512935"
    },
    {
      "nct_id": "NCT03109613",
      "title": "PEEP and V/Q Mismatch in Premature Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Insufficiency Syndrome of Newborn",
        "Infant, Premature, Diseases"
      ],
      "interventions": [
        {
          "name": "Positive end-expiratory pressure (PEEP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "28 Days",
        "sex": "ALL",
        "summary": "0 Days to 28 Days"
      },
      "enrollment_count": 12,
      "start_date": "2016-04-11",
      "completion_date": "2018-08-08",
      "has_results": false,
      "last_update_posted_date": "2020-11-17",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 3,
      "location_summary": "Newark, Delaware • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03109613"
    },
    {
      "nct_id": "NCT02165631",
      "title": "The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion Pressure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Open Angle Glaucoma",
        "Ocular Hypertension",
        "Pigment Dispersion Syndrome",
        "Pseudoexfoliation Glaucoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2014-08",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2016-03-14",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02165631"
    },
    {
      "nct_id": "NCT02388880",
      "title": "Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion (4hour)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Head Injury",
        "Intracranial Pathology",
        "Compromised Cerebral Perfusion"
      ],
      "interventions": [
        {
          "name": "ITPR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Advanced Circulatory Systems",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2015-02",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2019-04-22",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02388880"
    },
    {
      "nct_id": "NCT01205607",
      "title": "IRB-HSR# 14299: The Use of the Intrathoracic Pressure Regulator (ITPR) to Improve Cerebral Perfusion Pressure in Patients With Altered Intracranial Elastance",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "ITPR -5 mm Hg then -9 mm Hg",
          "type": "DEVICE"
        },
        {
          "name": "ITPR -9 & then -5mm Hg",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-05",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2010-09-20",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01205607"
    },
    {
      "nct_id": "NCT05170295",
      "title": "Noninvasive Monitoring of Cerebral Blood Flow Autoregulation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intracranial Pressure Increase",
        "Cerebral Edema"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ochsner Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2018-04-18",
      "completion_date": "2021-04-28",
      "has_results": false,
      "last_update_posted_date": "2021-12-27",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05170295"
    },
    {
      "nct_id": "NCT00696189",
      "title": "Effects of Nitrous Oxide on Intraocular Pressure",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post Operative Visual Loss"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2006-09",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2015-04-24",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00696189"
    },
    {
      "nct_id": "NCT00194441",
      "title": "Cerebral Perfusion Pressure (CPP) Management Information Feedback and Nursing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury",
        "Subarachnoid Hemorrhage"
      ],
      "interventions": [
        {
          "name": "Bedside display of cerebral perfusion pressure information",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 260,
      "start_date": "1999-04",
      "completion_date": "2008-09",
      "has_results": false,
      "last_update_posted_date": "2014-06-02",
      "last_synced_at": "2026-07-22T14:21:36.241Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00194441"
    }
  ]
}