{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Peri-Implantitis&page=2",
    "query": {
      "condition": "Peri-Implantitis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Peri-Implantitis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:51:57.667Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01870349",
      "title": "A Comparison of Inflammatory Mediators Surrounding Titanium or Zirconium Implant Abutments",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Peri-implantitis"
      ],
      "interventions": [
        {
          "name": "Gingival Crevicular Fluid Sampling",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Christopher Barwacz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 46,
      "start_date": "2010-12",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2018-02-27",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01870349"
    },
    {
      "nct_id": "NCT05024760",
      "title": "Antiseptic Effects on the Dental Implant Internal Surface Microbiome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Peri-Implantitis",
        "Peri-implant Mucositis",
        "Implant Infection",
        "Dental Implant Failed"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine",
          "type": "DRUG"
        },
        {
          "name": "Hydrogen Peroxide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Madigan Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 150,
      "start_date": "2022-07-28",
      "completion_date": "2025-11",
      "has_results": false,
      "last_update_posted_date": "2024-12-27",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Tacoma, Washington",
      "locations": [
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05024760"
    },
    {
      "nct_id": "NCT04827693",
      "title": "The Cortical Shield for Facial Bone Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tooth Loss",
        "Tooth Diseases",
        "Tooth Fracture",
        "Tooth Injuries",
        "Periodontal Bone Loss",
        "Periodontitis",
        "Peri-Implantitis",
        "Tooth Decay"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Verdugo, Fernando, DDS",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2019-01-03",
      "completion_date": "2021-04-05",
      "has_results": false,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04827693"
    },
    {
      "nct_id": "NCT01539564",
      "title": "Arestin - Use in Subjects With Peri-Implantitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Peri-Implantitis"
      ],
      "interventions": [
        {
          "name": "Minocycline HCl Microspheres",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "OraPharma",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 215,
      "start_date": "2012-04",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2014-06-26",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 9,
      "location_summary": "Los Angeles, California • Gainsville, Florida • Augusta, Georgia + 6 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Gainsville",
          "state": "Florida"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01539564"
    },
    {
      "nct_id": "NCT05699343",
      "title": "Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peri-Implantitis",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane)",
          "type": "PROCEDURE"
        },
        {
          "name": "InterOss Collagen (Bone xenograft)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Andrea Ravida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2023-01-30",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05699343"
    },
    {
      "nct_id": "NCT03100435",
      "title": "Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peri-Implantitis"
      ],
      "interventions": [
        {
          "name": "Er:YAG Laser",
          "type": "DEVICE"
        },
        {
          "name": "Carbon Fiber Curette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2017-04-20",
      "completion_date": "2018-10-18",
      "has_results": true,
      "last_update_posted_date": "2023-03-31",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03100435"
    },
    {
      "nct_id": "NCT04259840",
      "title": "Clinical Outcomes of Resective Surgical Treatment of Peri-Implantitis With or Without Implantoplasty",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Peri-Implantitis"
      ],
      "interventions": [
        {
          "name": "Observation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2019-12-05",
      "completion_date": "2020-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-11",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04259840"
    },
    {
      "nct_id": "NCT00662532",
      "title": "Antibiotic Study for Dental Implants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "Minocycline HCl",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "OraPharma",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2008-04",
      "completion_date": "2009-04",
      "has_results": true,
      "last_update_posted_date": "2011-12-12",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 4,
      "location_summary": "Aurora, Colorado • Ann Arbor, Michigan • Hazlet, New Jersey + 1 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Hazlet",
          "state": "New Jersey"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00662532"
    },
    {
      "nct_id": "NCT02625597",
      "title": "Assessment of the Effects of Different Implant Abutment Occluding Materials on Dental Implant Health Parameters and Microbiology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peri-Implantitis",
        "Dental Implant Failed",
        "Dental Implant Failure Nos"
      ],
      "interventions": [
        {
          "name": "Cotton Pellet",
          "type": "DEVICE"
        },
        {
          "name": "Polytetrafluoroethylene Tape",
          "type": "DEVICE"
        },
        {
          "name": "Synthetic Foam",
          "type": "DEVICE"
        },
        {
          "name": "Polyvinylsiloxane",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 8,
      "start_date": "2013-11",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-12-09",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02625597"
    },
    {
      "nct_id": "NCT06063876",
      "title": "Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peri-implant Mucositis",
        "Peri-Implantitis"
      ],
      "interventions": [
        {
          "name": "Induction of experimental peri-implant mucositis",
          "type": "PROCEDURE"
        },
        {
          "name": "Resolution of experimental peri-implant mucositis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-09-05",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-10-10",
      "last_synced_at": "2026-05-22T04:51:57.667Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06063876"
    }
  ]
}