{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perimenopausal+Disorder&page=2",
    "query": {
      "condition": "Perimenopausal Disorder",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perimenopausal+Disorder&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:45:35.670Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00229450",
      "title": "Estrogen and Perimenopausal Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depressive Disorder, Major",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "Estrogen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 17,
      "start_date": "2002-04",
      "completion_date": "2004-08",
      "has_results": false,
      "last_update_posted_date": "2020-02-25",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00229450"
    },
    {
      "nct_id": "NCT05282277",
      "title": "Examining the Effects of Estradiol on Neural and Molecular Response to Reward",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Psychosis",
        "Anhedonia"
      ],
      "interventions": [
        {
          "name": "Transdermal Estradiol",
          "type": "DRUG"
        },
        {
          "name": "Micronized Progesterone",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo Patch",
          "type": "DRUG"
        },
        {
          "name": "Raclopride C11",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 55 Years · Female only"
      },
      "enrollment_count": 103,
      "start_date": "2022-04-20",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05282277"
    },
    {
      "nct_id": "NCT07274371",
      "title": "A Study Comparing the Effects of Two Types of Natural Oils Used in a Bedtime Foot Massage Routine on Sleep and Emotional Well-Being in Perimenopausal Women.",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disturbances in Perimenopause"
      ],
      "interventions": [
        {
          "name": "Brahmi-Gotukola oil padabhyanga",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sesame oil Padabhyanga",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Saipriya Gowrishankar",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 55 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2025-11-06",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Fairfield, Iowa",
      "locations": [
        {
          "city": "Fairfield",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07274371"
    },
    {
      "nct_id": "NCT04444245",
      "title": "Ovarian Rejuvenation Using Platelet Rich Plasma (PRP) & Autologous Tissue Stromal Vascular Fraction (tSVF) and Cell Enriched tSVF",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ovarian Failure",
        "Perimenopausal Disorder",
        "Hormone Disturbance"
      ],
      "interventions": [
        {
          "name": "lipoaspiration harvest tSVF",
          "type": "PROCEDURE"
        },
        {
          "name": "Platelet Rich Plasma",
          "type": "PROCEDURE"
        },
        {
          "name": "Endovaginal Ultrasound",
          "type": "PROCEDURE"
        },
        {
          "name": "Cellular Isolation cSVF",
          "type": "DEVICE"
        },
        {
          "name": "Normal Saline (NS) .9% 10 mL Injection",
          "type": "DRUG"
        },
        {
          "name": "emulsification tSVF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Black Tie Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2022-07-15",
      "completion_date": "2025-08-15",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Colchester, Vermont",
      "locations": [
        {
          "city": "Colchester",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04444245"
    },
    {
      "nct_id": "NCT02174003",
      "title": "Whole Body Hyperthermia Registry Study",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression",
        "Anxiety",
        "PTSD",
        "Fibromyalgia",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "High intensity whole-body infrared heating",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2014-06",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02174003"
    },
    {
      "nct_id": "NCT04313751",
      "title": "Reducing Cardiovascular Disease Risk in Perimenopausal Latinas",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Risk Factor",
        "Health Behavior",
        "Physical Activity",
        "Self Efficacy",
        "Vascular Stiffness"
      ],
      "interventions": [
        {
          "name": "Education, Physical Activity, and Stress Management Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wait-list",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 49,
      "start_date": "2020-06-30",
      "completion_date": "2023-06-30",
      "has_results": true,
      "last_update_posted_date": "2024-08-20",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04313751"
    },
    {
      "nct_id": "NCT06798584",
      "title": "How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Iron Deficiency Anemia Treatment",
        "Iron Deficiency",
        "Iron Deficiency (Without Anemia)"
      ],
      "interventions": [
        {
          "name": "FeoSol Original Iron Supplement Tablets",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "21st Century Gelatin Capsules",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 240,
      "start_date": "2025-03-01",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06798584"
    },
    {
      "nct_id": "NCT03003949",
      "title": "The Menopause Transition: Estrogen Variability, Stress Reactivity and Mood",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Perimenopausal Disorder",
        "Stress, Emotional"
      ],
      "interventions": [
        {
          "name": "Estradiol Patch, 0.1 Mg/24 Hours Weekly Transdermal Film, Extended Release",
          "type": "DRUG"
        },
        {
          "name": "Placebo Patch",
          "type": "DRUG"
        },
        {
          "name": "Progesterone Capsule",
          "type": "DRUG"
        },
        {
          "name": "Placebo Oral Capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 60 Years · Female only"
      },
      "enrollment_count": 82,
      "start_date": "2017-01-24",
      "completion_date": "2020-05-10",
      "has_results": true,
      "last_update_posted_date": "2021-03-26",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03003949"
    },
    {
      "nct_id": "NCT07022340",
      "title": "Hemodynamics After Resistance Training",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perimenopause"
      ],
      "interventions": [
        {
          "name": "Resistance Training Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2025-06-06",
      "completion_date": "2026-03",
      "has_results": false,
      "last_update_posted_date": "2025-07-11",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07022340"
    },
    {
      "nct_id": "NCT00060736",
      "title": "The Effects of Estrogen Withdrawal on Mood Symptoms in Women",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Perimenopausal Depression",
        "Post Menopausal",
        "Healthy",
        "Depression"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 65 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2003-05-05",
      "completion_date": "2016-04-27",
      "has_results": false,
      "last_update_posted_date": "2019-12-16",
      "last_synced_at": "2026-05-22T08:45:35.670Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060736"
    }
  ]
}