{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perinatal+Hypoxia",
    "query": {
      "condition": "Perinatal Hypoxia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Perinatal+Hypoxia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T10:53:24.069Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02793999",
      "title": "Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic Ischemic Brain Injury",
        "Neonatal Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Near-Infrared Spectroscopy (NIRS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 125,
      "start_date": "2015-05",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2025-12-10",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02793999"
    },
    {
      "nct_id": "NCT03407729",
      "title": "Measuring Brain Activity of School Age Children",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Perinatal Hypoxia",
        "Dopamine",
        "Neurobehavioral Manifestations"
      ],
      "interventions": [
        {
          "name": "Magnetic Resonance Imaging",
          "type": "OTHER"
        },
        {
          "name": "Cognitive Performance Testing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "8 Years to 15 Years"
      },
      "enrollment_count": 21,
      "start_date": "2018-06-08",
      "completion_date": "2020-02-17",
      "has_results": true,
      "last_update_posted_date": "2022-10-10",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03407729"
    },
    {
      "nct_id": "NCT00005772",
      "title": "Whole-Body Cooling for Birth Asphyxia in Term Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn",
        "Hypoxia-Ischemia, Brain"
      ],
      "interventions": [
        {
          "name": "Induced hypothermia",
          "type": "DEVICE"
        },
        {
          "name": "Control",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "Up to 6 Hours"
      },
      "enrollment_count": 208,
      "start_date": "1999-10",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2019-03-22",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 16,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005772"
    },
    {
      "nct_id": "NCT03996317",
      "title": "Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perinatal Death",
        "Respiratory Distress Syndrome, Newborn",
        "Hypoxic-Ischemic Encephalopathy",
        "Neonatal Seizure",
        "Meconium Aspiration Syndrome",
        "Intracranial Hemorrhages",
        "Neonatal Hypotension"
      ],
      "interventions": [
        {
          "name": "Room air",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2021-06",
      "completion_date": "2022-12-30",
      "has_results": false,
      "last_update_posted_date": "2021-08-17",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03996317"
    },
    {
      "nct_id": "NCT05013736",
      "title": "Baby Brain Recovery Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Perinatal Stroke"
      ],
      "interventions": [
        {
          "name": "Magnetic Resonance Imaging",
          "type": "DEVICE"
        },
        {
          "name": "Behavioral Assessments",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Non invasive Transcranial Magnetic Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "24 Months",
        "sex": "ALL",
        "summary": "0 Years to 24 Months"
      },
      "enrollment_count": 65,
      "start_date": "2022-07-26",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05013736"
    },
    {
      "nct_id": "NCT00830531",
      "title": "Pilot Study of Bumetanide for Newborn Seizures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Seizures"
      ],
      "interventions": [
        {
          "name": "Bumetanide",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline as Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Soul, Janet , M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "44 Weeks",
        "sex": "ALL",
        "summary": "Up to 44 Weeks"
      },
      "enrollment_count": 43,
      "start_date": "2010-01",
      "completion_date": "2019-01",
      "has_results": false,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00830531"
    },
    {
      "nct_id": "NCT01765218",
      "title": "Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hypoxic Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Topiramate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kristin R Hoffman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "Up to 6 Hours"
      },
      "enrollment_count": 34,
      "start_date": "2013-02",
      "completion_date": "2022-01-27",
      "has_results": true,
      "last_update_posted_date": "2024-06-11",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01765218"
    },
    {
      "nct_id": "NCT01192776",
      "title": "Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Newborn",
        "Hypoxia, Brain",
        "Hypoxia-Ischemia, Brain",
        "Encephalopathy, Hypoxic-Ischemic",
        "Hypoxic-Ischemic Encephalopathy",
        "Ischemic-Hypoxic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Whole-body Cooling",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "Up to 6 Hours"
      },
      "enrollment_count": 364,
      "start_date": "2010-09",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01192776"
    },
    {
      "nct_id": "NCT00614744",
      "title": "Late Hypothermia for Hypoxic-Ischemic Encephalopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Newborn",
        "Hypoxia, Brain",
        "Hypoxia-Ischemia, Brain",
        "Encephalopathy, Hypoxic-Ischemic",
        "Hypoxic-Ischemic Encephalopathy",
        "Ischemic-Hypoxic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Hypothermia",
          "type": "PROCEDURE"
        },
        {
          "name": "Normothermic Control",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Hours",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "6 Hours to 24 Hours"
      },
      "enrollment_count": 168,
      "start_date": "2008-04",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2021-03-09",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 22,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00614744"
    },
    {
      "nct_id": "NCT06429007",
      "title": "A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypoxic-Ischemic Encephalopathy",
        "HIE",
        "Neurodevelopment",
        "Infant Development"
      ],
      "interventions": [
        {
          "name": "Metformin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "3 Months to 6 Months"
      },
      "enrollment_count": 30,
      "start_date": "2025-10-01",
      "completion_date": "2029-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-09-02T10:53:24.069Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06429007"
    }
  ]
}