{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontal+Bone+Loss",
    "query": {
      "condition": "Periodontal Bone Loss"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 42,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontal+Bone+Loss&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T03:13:58.147Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02953392",
      "title": "Implant-Abutment Interface Design on Bone and Soft Tissue Levels Around Implants Placed Using Different Transcrestal Sinus Floor Elevation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Loss"
      ],
      "interventions": [
        {
          "name": "Anorganic Bovine Bone Graft Material",
          "type": "DEVICE"
        },
        {
          "name": "Collagen Membrane",
          "type": "DEVICE"
        },
        {
          "name": "Shelta Platform Switching Premium Implants",
          "type": "DEVICE"
        },
        {
          "name": "Shelta Platform Matching Premium Implants",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU College of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 38,
      "start_date": "2016-05-10",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02953392"
    },
    {
      "nct_id": "NCT02802319",
      "title": "Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alveolar Bone Loss"
      ],
      "interventions": [
        {
          "name": "Porcine Xenograft (Zcore)",
          "type": "DEVICE"
        },
        {
          "name": "Bovine Xenograft (Bio-Oss)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 44,
      "start_date": "2016-07",
      "completion_date": "2018-09",
      "has_results": true,
      "last_update_posted_date": "2019-01-08",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02802319"
    },
    {
      "nct_id": "NCT06077513",
      "title": "Ti-Mesh Frame Comparison for Alveolar Bone Augmentation",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Loss"
      ],
      "interventions": [
        {
          "name": "CAD-CAM designed and preprinted Ti-Mesh frame",
          "type": "PROCEDURE"
        },
        {
          "name": "Conventional chairside fabrication of Ti-Mesh frame",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-01-25",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06077513"
    },
    {
      "nct_id": "NCT01836783",
      "title": "Bone Augmentation Techniques in Extraction Sockets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Loss"
      ],
      "interventions": [
        {
          "name": "Amnion Allograft",
          "type": "OTHER"
        },
        {
          "name": "Allograft",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2013-01",
      "completion_date": "2023-10",
      "has_results": true,
      "last_update_posted_date": "2024-06-10",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01836783"
    },
    {
      "nct_id": "NCT01728844",
      "title": "GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alveolar Bone Loss",
        "Periodontal Diseases"
      ],
      "interventions": [
        {
          "name": "beta-tricalcium phosphate alone",
          "type": "DEVICE"
        },
        {
          "name": "GFeBGS 0.1%",
          "type": "DEVICE"
        },
        {
          "name": "GFeBGS 0.3%",
          "type": "DEVICE"
        },
        {
          "name": "GFeBGS 0.4%",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sunstar Americas",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 88,
      "start_date": "2012-10",
      "completion_date": "2014-08",
      "has_results": true,
      "last_update_posted_date": "2020-09-17",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 6,
      "location_summary": "Birmingham, Alabama • Fullerton, California • Aurora, Colorado + 3 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01728844"
    },
    {
      "nct_id": "NCT00277706",
      "title": "Impact of Parathyroid Hormone (PTH) on Osseous Cavity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bone Loss",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "Periodontal surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "FORTEO",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Vitamin D and Calcium",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "30 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2004-08",
      "completion_date": "2009-07",
      "has_results": false,
      "last_update_posted_date": "2009-10-07",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00277706"
    },
    {
      "nct_id": "NCT05157009",
      "title": "Immediate Implant Outcomes With and Without Bone Augmentation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Loss",
        "Bone Loss, Alveolar",
        "Dental Diseases",
        "Dental Trauma"
      ],
      "interventions": [
        {
          "name": "implant placement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Verdugo, Fernando, DDS",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2021-10-01",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-04-26",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "San Gabriel, California",
      "locations": [
        {
          "city": "San Gabriel",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05157009"
    },
    {
      "nct_id": "NCT02972788",
      "title": "Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Periodontal Bone Loss"
      ],
      "interventions": [
        {
          "name": "Enamel Matrix Proteins Derivative",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 50,
      "start_date": "2017-02-01",
      "completion_date": "2018-09-20",
      "has_results": false,
      "last_update_posted_date": "2023-12-01",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02972788"
    },
    {
      "nct_id": "NCT04255342",
      "title": "Azento IIS 3 Year Outcomes Implant Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Loss"
      ],
      "interventions": [
        {
          "name": "Implant Placement and Temporary Crown using AstraTech Implant System EV, Final Crown Delivery",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Christopher Barwacz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 25,
      "start_date": "2020-01-29",
      "completion_date": "2024-01-30",
      "has_results": true,
      "last_update_posted_date": "2024-10-03",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04255342"
    },
    {
      "nct_id": "NCT05887128",
      "title": "Accuracy of Extra-oral Bite-wing Radiography in Detecting Calculus and Crestal Bone Loss",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontitis",
        "Calculus, Dental",
        "Bone Loss, Alveolar"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 80,
      "start_date": "2023-06-01",
      "completion_date": "2025-06-01",
      "has_results": false,
      "last_update_posted_date": "2023-12-06",
      "last_synced_at": "2026-07-22T03:13:58.147Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05887128"
    }
  ]
}