{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontal+Diseases",
    "query": {
      "condition": "Periodontal Diseases"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 400,
    "total_pages": 40,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontal+Diseases&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:45:10.103Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01489839",
      "title": "Biomarkers of Periodontal Disease Progression",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontal Disease"
      ],
      "interventions": [
        {
          "name": "Periodontal therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Forsyth Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2012-01",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2018-02-07",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 5,
      "location_summary": "Edwardsville, Illinois • Cambridge, Massachusetts • Ann Arbor, Michigan + 2 more",
      "locations": [
        {
          "city": "Edwardsville",
          "state": "Illinois"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01489839"
    },
    {
      "nct_id": "NCT00277745",
      "title": "Integrated Microfluidic System for Oral Diagnostics",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "miniaturized microfluidic system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2005-06",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2015-12-14",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00277745"
    },
    {
      "nct_id": "NCT01782170",
      "title": "Efficacy of Iocide Oral Rinse Against Gingival Inflammation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Gingivitis",
        "Investigation of Biological Markers of Inflammation"
      ],
      "interventions": [
        {
          "name": "Iocide Oral Rinse",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Biomedical Development Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2013-02",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2013-08-14",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01782170"
    },
    {
      "nct_id": "NCT01799226",
      "title": "Study of the Anti-Inflammatory Effects of Colgate Total® During an Experimental Gingivitis Model",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Toothpaste without triclosan",
          "type": "OTHER"
        },
        {
          "name": "Triclosan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 32,
      "start_date": "2013-03",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2016-01-13",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01799226"
    },
    {
      "nct_id": "NCT02794012",
      "title": "Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rheumatoid Arthritis",
        "Periodontal Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 146,
      "start_date": "2016-07",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-09",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02794012"
    },
    {
      "nct_id": "NCT00569075",
      "title": "Apoptic Biomarkers of Periodontal Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "collection of gingival crevicular fluid",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2006-10",
      "completion_date": "2009-10",
      "has_results": false,
      "last_update_posted_date": "2017-05-10",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00569075"
    },
    {
      "nct_id": "NCT06966492",
      "title": "Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingival Inflammation"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Toothpaste (SnF)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-05",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06966492"
    },
    {
      "nct_id": "NCT02980211",
      "title": "Treatment of Post-Extraction Dehisced Socket - A Case Series Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tooth Loss"
      ],
      "interventions": [
        {
          "name": "Alveolar Ridge Reconstruction",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gustavo Avila-Ortiz DDS, MS, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2017-03-01",
      "completion_date": "2018-05-17",
      "has_results": true,
      "last_update_posted_date": "2020-02-05",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02980211"
    },
    {
      "nct_id": "NCT04020458",
      "title": "Dental Intervention Plan for Chronic Kidney Disease Patients Awaiting or With Kidney Transplant",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Disease",
        "Chronic Periodontitis, Generalized, Moderate"
      ],
      "interventions": [
        {
          "name": "dental intervention",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 11,
      "start_date": "2018-11-09",
      "completion_date": "2022-01-04",
      "has_results": false,
      "last_update_posted_date": "2023-07-21",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04020458"
    },
    {
      "nct_id": "NCT01094639",
      "title": "Periodontal Infection and Systemic Inflammation in Renal Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontitis",
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "Scaling root planing",
          "type": "PROCEDURE"
        },
        {
          "name": "Supragingival Prophylaxis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 52,
      "start_date": "2009-08",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2016-10-25",
      "last_synced_at": "2026-05-22T06:45:10.103Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01094639"
    }
  ]
}