{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontitis",
    "query": {
      "condition": "Periodontitis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 113,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontitis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:17:27.325Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00277745",
      "title": "Integrated Microfluidic System for Oral Diagnostics",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "miniaturized microfluidic system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2005-06",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2015-12-14",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00277745"
    },
    {
      "nct_id": "NCT00569075",
      "title": "Apoptic Biomarkers of Periodontal Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "collection of gingival crevicular fluid",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2006-10",
      "completion_date": "2009-10",
      "has_results": false,
      "last_update_posted_date": "2017-05-10",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00569075"
    },
    {
      "nct_id": "NCT04020458",
      "title": "Dental Intervention Plan for Chronic Kidney Disease Patients Awaiting or With Kidney Transplant",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Disease",
        "Chronic Periodontitis, Generalized, Moderate"
      ],
      "interventions": [
        {
          "name": "dental intervention",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 11,
      "start_date": "2018-11-09",
      "completion_date": "2022-01-04",
      "has_results": false,
      "last_update_posted_date": "2023-07-21",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04020458"
    },
    {
      "nct_id": "NCT01094639",
      "title": "Periodontal Infection and Systemic Inflammation in Renal Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontitis",
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "Scaling root planing",
          "type": "PROCEDURE"
        },
        {
          "name": "Supragingival Prophylaxis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 52,
      "start_date": "2009-08",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2016-10-25",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01094639"
    },
    {
      "nct_id": "NCT06574152",
      "title": "Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apical Periodontitis",
        "Endodontically Treated Teeth",
        "Endodontic Disease",
        "Apical Cyst",
        "Apical Granuloma",
        "Periradicular Disease",
        "Previous Endodontic Treatment"
      ],
      "interventions": [
        {
          "name": "PBM treatment",
          "type": "DEVICE"
        },
        {
          "name": "PBM sham treatment",
          "type": "DEVICE"
        },
        {
          "name": "EMS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2024-08-20",
      "completion_date": "2025-07-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-29",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06574152"
    },
    {
      "nct_id": "NCT00594334",
      "title": "Effect of Actonel on Periodontal Health of Postmenopausal Women",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Periodontal Disease"
      ],
      "interventions": [
        {
          "name": "Risedronate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 80 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2008-01",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00594334"
    },
    {
      "nct_id": "NCT00097656",
      "title": "MOTOR: Maternal Oral Therapy to Reduce Obstetric Risk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy Related",
        "Periodontitis",
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "multi-center, randomized, controled periodontal therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "16 Years and older · Female only"
      },
      "enrollment_count": 1800,
      "start_date": "2004-02",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2018-01-29",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00097656"
    },
    {
      "nct_id": "NCT03690479",
      "title": "The Impact of a Modified Probe Tip Design on Patient Perception of Discomfort on Probing and Clinical Parameters Using the Florida Probe® System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontitis",
        "Diagnoses Disease"
      ],
      "interventions": [
        {
          "name": "Florida Probe Straight Tip Probe",
          "type": "DEVICE"
        },
        {
          "name": "Ball Tip Probe",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2013-04-04",
      "completion_date": "2017-12-14",
      "has_results": false,
      "last_update_posted_date": "2018-10-02",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03690479"
    },
    {
      "nct_id": "NCT06890689",
      "title": "Effectiveness of Scaling and Root Planing in Deeper Pockets",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontal Disease",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "Scaling and root planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Texas A&M University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 110,
      "start_date": "2025-01-01",
      "completion_date": "2026-08-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-09",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06890689"
    },
    {
      "nct_id": "NCT06776289",
      "title": "Endodontic Microsurgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Apical Periodontitis"
      ],
      "interventions": [
        {
          "name": "Platelet rich fibrin",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Mark Schachman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-03",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-16",
      "last_synced_at": "2026-05-22T09:17:27.325Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06776289"
    }
  ]
}