{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontitis%2C+Chronic&page=2",
    "query": {
      "condition": "Periodontitis, Chronic",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontitis%2C+Chronic&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T13:16:13.944Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03262701",
      "title": "Adjunctive Hydrogen Peroxide for Periodontal Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Periodontitis, Chronic"
      ],
      "interventions": [
        {
          "name": "Hydrogen Peroxide Gel, 13 weeks",
          "type": "DRUG"
        },
        {
          "name": "Hydrogen Peroxide Gel, 26 weeks",
          "type": "DRUG"
        },
        {
          "name": "Scaling and Root planing group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 42,
      "start_date": "2018-04-02",
      "completion_date": "2021-02-08",
      "has_results": true,
      "last_update_posted_date": "2022-12-21",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03262701"
    },
    {
      "nct_id": "NCT03553095",
      "title": "Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Periodontal Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 92,
      "start_date": "2018-07-12",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-12",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03553095"
    },
    {
      "nct_id": "NCT03241511",
      "title": "Novel PAradigm to Improve Inflammatory Burden in ESRD (rePAIR): A Pilot and Feasibility Randomized Controlled Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis",
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2017-11-07",
      "completion_date": "2020-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-06-05",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241511"
    },
    {
      "nct_id": "NCT01098448",
      "title": "Control of Periodontal Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "scaling and root planing",
          "type": "OTHER"
        },
        {
          "name": "local tetracycline",
          "type": "DRUG"
        },
        {
          "name": "systemic metronidazole and amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "surgery",
          "type": "OTHER"
        },
        {
          "name": "local antibiotics and systemic metronidazole and amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "local tetracycline and periodontal surgery",
          "type": "OTHER"
        },
        {
          "name": "periodontal surgery and systemic metronidazole and amoxicillin",
          "type": "OTHER"
        },
        {
          "name": "surgery, local tetracycline, systemic metronidazole and amoxicillin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "The Forsyth Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 187,
      "start_date": "1999-09",
      "completion_date": "2004-12",
      "has_results": false,
      "last_update_posted_date": "2010-04-02",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01098448"
    },
    {
      "nct_id": "NCT04978324",
      "title": "Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Periodontitis Chronic Generalized Severe",
        "Periodontitis Chronic Generalized Moderate"
      ],
      "interventions": [
        {
          "name": "leukocyte platelet rich fibrin (L-PRF)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Scaling and Root Planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2022-05",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2022-05-12",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04978324"
    },
    {
      "nct_id": "NCT00529555",
      "title": "Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Adult Periodontitis"
      ],
      "interventions": [
        {
          "name": "minocycline HCl 2.1%",
          "type": "DRUG"
        },
        {
          "name": "Scaling and root planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Sunstar Americas",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 602,
      "start_date": "2006-01",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2014-05-09",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • San Francisco, California • Gainsville, Florida + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Gainsville",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00529555"
    },
    {
      "nct_id": "NCT06149585",
      "title": "Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Edentulous Mouth",
        "Periodontal Diseases",
        "Periodontitis, Adult",
        "Microbial Colonization"
      ],
      "interventions": [
        {
          "name": "Microbial Sampling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2023-08-16",
      "completion_date": "2028-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06149585"
    },
    {
      "nct_id": "NCT00223327",
      "title": "Measurement of Bite Force in Humans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Pulp Necrosis",
        "Periapical Periodontitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "16 Years to 60 Years"
      },
      "enrollment_count": 89,
      "start_date": "2005-03",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2012-03-09",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00223327"
    },
    {
      "nct_id": "NCT01215201",
      "title": "Diode Laser Study for Periodontal Maintenance Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontal Diseases",
        "Periodontitis, Apical, Chronic Nonsuppurative",
        "Suppuration of Gingival Crevice"
      ],
      "interventions": [
        {
          "name": "Scaling and Root Planing",
          "type": "PROCEDURE"
        },
        {
          "name": "Diode Laser + Scaling and Root Planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2010-05-01",
      "completion_date": "2011-07-01",
      "has_results": false,
      "last_update_posted_date": "2023-09-15",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01215201"
    },
    {
      "nct_id": "NCT00223379",
      "title": "Longitudinal Endodontic Study of Apical Preparation Size",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Apical Periodontitis of Pulpal Origin"
      ],
      "interventions": [
        {
          "name": "Endodontic procedure with varied apical preparation size",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 36,
      "start_date": "2002-12",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2012-03-08",
      "last_synced_at": "2026-07-23T13:16:13.944Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00223379"
    }
  ]
}