{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periodontitis%2C+Diabetes+Mellitus+Type+2",
    "query": {
      "condition": "Periodontitis, Diabetes Mellitus Type 2"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T05:01:57.418Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01711385",
      "title": "Undiagnosed Diabetes in a Dental Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prediabetic State",
        "Type 2 Diabetes Mellitus With Oral Complications",
        "Periodontal Pocket",
        "Tooth Loss"
      ],
      "interventions": [
        {
          "name": "Enhanced intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 101,
      "start_date": "2009-04",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2021-08-17",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01711385"
    },
    {
      "nct_id": "NCT07298057",
      "title": "Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Periodontitis, Diabetes Mellitus Type 2"
      ],
      "interventions": [
        {
          "name": "local antibiotic application of topical minocycline",
          "type": "DRUG"
        },
        {
          "name": "Scaling and Root Planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2026-02-06",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07298057"
    },
    {
      "nct_id": "NCT02671136",
      "title": "Hyperbaric Oxygen Therapy as Adjunctive Therapy to Scaling and Root-planing in the Management of Periodontitis in Patients With Type 2 Diabetes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "Hyperbaric Oxygen therapy",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Wound Therapies",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 3,
      "start_date": "2016-08-18",
      "completion_date": "2017-03-31",
      "has_results": true,
      "last_update_posted_date": "2019-03-13",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02671136"
    },
    {
      "nct_id": "NCT00801164",
      "title": "Exploratory Study of Iocide Oral Rinse in a Diabetic Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Diabetes Type 2",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "Frio Mouth Rinse Placebo",
          "type": "DRUG"
        },
        {
          "name": "Frio Mouth Rinse",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Biomedical Development Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2008-12",
      "completion_date": "2010-06",
      "has_results": false,
      "last_update_posted_date": "2012-02-02",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00801164"
    },
    {
      "nct_id": "NCT00997178",
      "title": "Diabetes and Periodontal Therapy Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Periodontitis",
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Non-surgical periodontal therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Delayed non-surgical periodontal therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 514,
      "start_date": "2009-10",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2014-01-20",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 8,
      "location_summary": "Birmingham, Alabama • Minneapolis, Minnesota • Stony Brook, New York + 2 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00997178"
    },
    {
      "nct_id": "NCT06582056",
      "title": "Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontal Disease"
      ],
      "interventions": [
        {
          "name": "Investigational Procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 226,
      "start_date": "2024-10-09",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-28",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 4,
      "location_summary": "Iowa City, Iowa • Somerville, Massachusetts • Stony Brook, New York + 1 more",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Somerville",
          "state": "Massachusetts"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06582056"
    },
    {
      "nct_id": "NCT01881074",
      "title": "Periodontal Treatment Response in Type II Diabetic Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Type II Diabetes",
        "Periodontal Disease"
      ],
      "interventions": [
        {
          "name": "Triclosan containing toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Non-triclosan containing toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 74,
      "start_date": "2012-06",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2018-09-17",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01881074"
    },
    {
      "nct_id": "NCT04830969",
      "title": "Impact of Periodontal Therapy on Patients With Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes Mellitus, Type II",
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate oral rinse",
          "type": "DRUG"
        },
        {
          "name": "Scaling & Root Planing",
          "type": "PROCEDURE"
        },
        {
          "name": "Soft Picks",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 116,
      "start_date": "2016-11-08",
      "completion_date": "2021-01-28",
      "has_results": true,
      "last_update_posted_date": "2023-03-01",
      "last_synced_at": "2026-06-27T05:01:57.418Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04830969"
    }
  ]
}