{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periorbital",
    "query": {
      "condition": "Periorbital"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periorbital&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-25T03:14:53.137Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07214272",
      "title": "A Phase 4 Clinical Study to Investigate the Effectiveness and Safety of Skin Resurfacing",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Resurfacing"
      ],
      "interventions": [
        {
          "name": "Fraxel® FTX Laser System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bausch Health Americas, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 49,
      "start_date": "2025-10-17",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-06-11",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 5,
      "location_summary": "La Jolla, California • Miami, Florida • Naperville, Illinois + 2 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Naperville",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07214272"
    },
    {
      "nct_id": "NCT01401803",
      "title": "Brow Lifting With Dysport",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Brow Ptosis",
        "Lid Ptosis"
      ],
      "interventions": [
        {
          "name": "Dysport",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kenneth Beer",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 24,
      "start_date": "2011-09",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2013-09-26",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 1,
      "location_summary": "West Palm Beach, Florida",
      "locations": [
        {
          "city": "West Palm Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01401803"
    },
    {
      "nct_id": "NCT04639713",
      "title": "Clinical Study Evaluating the Safety and Effectiveness of The Tixel Fractional System in The Treatment of Periorbital Wrinkles",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle",
        "Periorbital",
        "Tixel 2",
        "Fractional",
        "Resurfacing"
      ],
      "interventions": [
        {
          "name": "Tixel 2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Novoxel Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "35 Years to 70 Years"
      },
      "enrollment_count": 51,
      "start_date": "2021-03-02",
      "completion_date": "2022-04-04",
      "has_results": true,
      "last_update_posted_date": "2024-03-19",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • New York, New York",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04639713"
    },
    {
      "nct_id": "NCT03454672",
      "title": "A Safety and Effectiveness Study of the Tixel Device, (Fractional Peri-orbital Wrinkles Treatment ) Compared With Laser",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Tixel",
          "type": "DEVICE"
        },
        {
          "name": "Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Novoxel Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 68,
      "start_date": "2018-03-12",
      "completion_date": "2020-09-04",
      "has_results": true,
      "last_update_posted_date": "2024-08-23",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03454672"
    },
    {
      "nct_id": "NCT05089851",
      "title": "Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkles",
        "Photoaging",
        "Fine Lines"
      ],
      "interventions": [
        {
          "name": "Onabotulinumtoxin A",
          "type": "PROCEDURE"
        },
        {
          "name": "Facial Cleanser",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Facial Moisturizer",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Sunscreen",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 29,
      "start_date": "2020-08-23",
      "completion_date": "2021-06-03",
      "has_results": false,
      "last_update_posted_date": "2021-10-28",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 3,
      "location_summary": "Fort Lauderdale, Florida • Coralville, Iowa • Columbus, Ohio",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Coralville",
          "state": "Iowa"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05089851"
    },
    {
      "nct_id": "NCT05807620",
      "title": "A 12 Week Study to Evaluate the Efficacy of an Eye Cream",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periorbital Hyperpigmentation",
        "Periorbital Edema",
        "Fine Lines",
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Gentle Cleansing Lotion",
          "type": "OTHER"
        },
        {
          "name": "Facial Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Sunscreen SPF 30",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2022-01-01",
      "completion_date": "2022-07-01",
      "has_results": false,
      "last_update_posted_date": "2023-11-30",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 1,
      "location_summary": "Teaneck, New Jersey",
      "locations": [
        {
          "city": "Teaneck",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05807620"
    },
    {
      "nct_id": "NCT01368900",
      "title": "Reducing Wrinkles Around the Eyes Using the Ulthera® System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periorbital Wrinkles"
      ],
      "interventions": [
        {
          "name": "Ulthera® System treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ulthera, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 68,
      "start_date": "2011-03",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2017-12-13",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 2,
      "location_summary": "Hunt Valley, Maryland • Nashville, Tennessee",
      "locations": [
        {
          "city": "Hunt Valley",
          "state": "Maryland"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01368900"
    },
    {
      "nct_id": "NCT03280069",
      "title": "Evaluation of Ocular Surface Changes Following RF Electrocoagulation Treatment of the Periorbital Region",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Skin Laxity",
        "Meibomian Gland Dysfunction"
      ],
      "interventions": [
        {
          "name": "THERMIeyes® 20 RF System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ophthalmic Consultants of Long Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 30,
      "start_date": "2017-07-25",
      "completion_date": "2019-07-31",
      "has_results": false,
      "last_update_posted_date": "2017-09-12",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 1,
      "location_summary": "Lynbrook, New York",
      "locations": [
        {
          "city": "Lynbrook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03280069"
    },
    {
      "nct_id": "NCT04103619",
      "title": "Energy-Based Lower Eyelid Rejuvenation - Proof of Concept for InMode AccuTite With or Without Morpheus8",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periorbital Edema"
      ],
      "interventions": [
        {
          "name": "AccuTite",
          "type": "DEVICE"
        },
        {
          "name": "AccuTite + Morpheus 8",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "InMode MD Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "29 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "29 Years to 75 Years"
      },
      "enrollment_count": 12,
      "start_date": "2019-05-16",
      "completion_date": "2021-12-13",
      "has_results": false,
      "last_update_posted_date": "2022-01-10",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 2,
      "location_summary": "Sarasota, Florida • Youngstown, Ohio",
      "locations": [
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04103619"
    },
    {
      "nct_id": "NCT06143033",
      "title": "A Clinical Trial to Evaluate the Effects of an Eye Serum on Improving the Appearance of the Periorbital Area",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periorbital Area"
      ],
      "interventions": [
        {
          "name": "DIME Beauty Luminosity Eye Serum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dime Beauty Co.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 35,
      "start_date": "2023-08-21",
      "completion_date": "2024-02-15",
      "has_results": false,
      "last_update_posted_date": "2024-02-22",
      "last_synced_at": "2026-07-25T03:14:53.137Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06143033"
    }
  ]
}