{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Periorbital+Hyperpigmentation",
    "query": {
      "condition": "Periorbital Hyperpigmentation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T15:10:11.939Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03400202",
      "title": "Physiopathologic Aspects and Quality of Life in Participants With Eye Dark Circles",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periorbital Hyperpigmentation"
      ],
      "interventions": [
        {
          "name": "Skin imaging",
          "type": "DEVICE"
        },
        {
          "name": "Facial cleanser",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "25 Years to 50 Years"
      },
      "enrollment_count": 44,
      "start_date": "2018-02-02",
      "completion_date": "2018-11-07",
      "has_results": false,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-07-22T15:10:11.939Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03400202"
    },
    {
      "nct_id": "NCT05807620",
      "title": "A 12 Week Study to Evaluate the Efficacy of an Eye Cream",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periorbital Hyperpigmentation",
        "Periorbital Edema",
        "Fine Lines",
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Gentle Cleansing Lotion",
          "type": "OTHER"
        },
        {
          "name": "Facial Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Sunscreen SPF 30",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2022-01-01",
      "completion_date": "2022-07-01",
      "has_results": false,
      "last_update_posted_date": "2023-11-30",
      "last_synced_at": "2026-07-22T15:10:11.939Z",
      "location_count": 1,
      "location_summary": "Teaneck, New Jersey",
      "locations": [
        {
          "city": "Teaneck",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05807620"
    },
    {
      "nct_id": "NCT01172522",
      "title": "Topical Treatment of Under Eye Dark Circles and Swelling",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Edema"
      ],
      "interventions": [
        {
          "name": "Fexofenadine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Connecticut Sinus Center, PC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2010-09",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2015-02-19",
      "last_synced_at": "2026-07-22T15:10:11.939Z",
      "location_count": 1,
      "location_summary": "Paramus, New Jersey",
      "locations": [
        {
          "city": "Paramus",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01172522"
    }
  ]
}