{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Peripheral+Artery+Disease+%28PAD%29%3B+Intermittent+Claudication",
    "query": {
      "condition": "Peripheral Artery Disease (PAD); Intermittent Claudication"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 124,
    "total_pages": 13,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Peripheral+Artery+Disease+%28PAD%29%3B+Intermittent+Claudication&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T06:35:21.778Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00311805",
      "title": "Autologous CD34+ Stem Cell Injection for Severe Intermittent Claudication (Leg Pain)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Peripheral Artery Disease",
        "Severe Intermittent Claudication"
      ],
      "interventions": [
        {
          "name": "Autologous Stem Cells (CD34+)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Losordo, Douglas, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2006-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2015-03-31",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Chicago, Illinois",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00311805"
    },
    {
      "nct_id": "NCT07144150",
      "title": "EVERO Drug-coated Balloon (DCB) Randomized Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Vascular Disease",
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "Evero DCB",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Paclitaxel DCB",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Cook Research Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 410,
      "start_date": "2026-04-17",
      "completion_date": "2032-10",
      "has_results": false,
      "last_update_posted_date": "2026-06-23",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 4,
      "location_summary": "Gainesville, Florida • Jacksonville, Florida • Miami, Florida + 1 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07144150"
    },
    {
      "nct_id": "NCT00146666",
      "title": "Evaluation of FM220 in Patients With Peripheral Arterial Disease (PAD)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Intermittent Claudication"
      ],
      "interventions": [
        {
          "name": "Intermittent compression",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "FlowMedic",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2005-09",
      "completion_date": "2006-09",
      "has_results": false,
      "last_update_posted_date": "2009-12-17",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • San Antonio, Texas",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00146666"
    },
    {
      "nct_id": "NCT02719665",
      "title": "THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Claudication",
        "Claudication, Intermittent",
        "Vascular Occlusion",
        "Vascular Calcification",
        "Vascular Diseases",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "SPM Emulsion, Dose-modality",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "SPM Softgel, Dose-Modality",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Softgel",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 30,
      "start_date": "2016-03",
      "completion_date": "2020-12-15",
      "has_results": false,
      "last_update_posted_date": "2021-05-07",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02719665"
    },
    {
      "nct_id": "NCT02384980",
      "title": "Saving Life and Limb: FES for the Elderly With PAD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "FES (Gait MyoElectric Stimulator)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MultiCare Health System Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 43,
      "start_date": "2014-09",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-08-16",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 1,
      "location_summary": "Tacoma, Washington",
      "locations": [
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02384980"
    },
    {
      "nct_id": "NCT02842424",
      "title": "Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "Ramipril",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 70,
      "start_date": "2016-02-25",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02842424"
    },
    {
      "nct_id": "NCT01602159",
      "title": "Revascularization With Open Bypass Versus Angioplasty and STenting of the Lower Extremity Trial (ROBUST)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Superficial Femoral Artery Stenosis",
        "Superficial Femoral Artery Occlusion",
        "Claudication",
        "Rest Pain"
      ],
      "interventions": [
        {
          "name": "Open Bypass Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Angioplasty and Stenting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2009-07",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2018-09-28",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01602159"
    },
    {
      "nct_id": "NCT00032357",
      "title": "Does the Reduction of Total Body Iron Storage (TBIS) Alter Mortality in a Population of Patients With Advanced PVD?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atherosclerosis",
        "Intermittent Claudication",
        "Peripheral Vascular Diseases"
      ],
      "interventions": [
        {
          "name": "Ferritin reduction to 25 ng/ml by phlebotomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 1277,
      "start_date": "1999-05",
      "completion_date": "2005-09",
      "has_results": false,
      "last_update_posted_date": "2013-01-21",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 23,
      "location_summary": "Birmingham, Alabama • No. Little Rock, Arkansas • Long Beach, California + 20 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "No. Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00032357"
    },
    {
      "nct_id": "NCT06409949",
      "title": "MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "Walking assessment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "QOL Survey",
          "type": "OTHER"
        },
        {
          "name": "Ankle pressure at rest and after stress",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Muscle Oxygen",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum MitoQ Level",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Needle Biopsy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-06-01",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06409949"
    },
    {
      "nct_id": "NCT01890135",
      "title": "Zibotentan, an Endothelin Receptor Antagonist, Patients With Intermittent Claudication",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Intermittent Claudication"
      ],
      "interventions": [
        {
          "name": "Zibotentan (ZD4054)",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2013-06",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-08-02",
      "last_synced_at": "2026-06-26T06:35:21.778Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01890135"
    }
  ]
}