{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Peripheral+Vascular+Disease+%28PVD%29&page=23",
    "query": {
      "condition": "Peripheral Vascular Disease (PVD)",
      "page": 23
    },
    "page_size": 10
  },
  "pagination": {
    "page": 23,
    "page_size": 10,
    "total_count": 681,
    "total_pages": 69,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Peripheral+Vascular+Disease+%28PVD%29&page=24&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Peripheral+Vascular+Disease+%28PVD%29&page=22&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-15T00:26:50.103Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04800692",
      "title": "The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Claudication, Intermittent",
        "Peripheral Artery Disease",
        "Peripheral Vascular Diseases"
      ],
      "interventions": [
        {
          "name": "Tetrahydrobiopterin 10 mg/kg",
          "type": "DRUG"
        },
        {
          "name": "Tetrahydrobiopterin 20 mg/kg",
          "type": "DRUG"
        },
        {
          "name": "L-Ascorbate",
          "type": "DRUG"
        },
        {
          "name": "L-Arginine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Louis Messina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2021-06-15",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04800692"
    },
    {
      "nct_id": "NCT00378521",
      "title": "Dose Response Study of a Topical Gel for the Treatment of Raynaud's Phenomenon",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Raynaud's Disease",
        "Raynaud's Disease Secondary to Scleroderma",
        "Raynaud's Disease Secondary to Autoimmune Disease"
      ],
      "interventions": [
        {
          "name": "MQX-503",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "MediQuest Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 15,
      "start_date": "2006-07",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2007-05-30",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 1,
      "location_summary": "Renton, Washington",
      "locations": [
        {
          "city": "Renton",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00378521"
    },
    {
      "nct_id": "NCT01901224",
      "title": "Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Peripheral Artery Disease"
      ],
      "interventions": [
        {
          "name": "Metformin 1000 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2013-07",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2018-09-24",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01901224"
    },
    {
      "nct_id": "NCT04774159",
      "title": "Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Atherosclerosis of Extremities",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Colchicine 0.5 MG Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "Colchicine-Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Population Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6150,
      "start_date": "2021-05-06",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2026-10-05",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 24,
      "location_summary": "New Haven, Connecticut • Gainesville, Florida • Tampa, Florida + 19 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04774159"
    },
    {
      "nct_id": "NCT02091921",
      "title": "Switch to Ticagrelor in Critical Limb Ischemia Anti-platelet Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Critical Limb Ischemia"
      ],
      "interventions": [
        {
          "name": "Ticagrelor",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 53,
      "start_date": "2014-02-16",
      "completion_date": "2016-11-30",
      "has_results": true,
      "last_update_posted_date": "2019-06-19",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02091921"
    },
    {
      "nct_id": "NCT03421561",
      "title": "ILLUMENATE Pivotal Post-Approval Study (PAS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Artery Disease"
      ],
      "interventions": [
        {
          "name": "Stellarex 0.035\" OTW Drug-coated Angioplasty Balloon",
          "type": "DEVICE"
        },
        {
          "name": "EverCross™ 0.035 PTA Balloon Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Spectranetics Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2013-06-18",
      "completion_date": "2020-10-06",
      "has_results": true,
      "last_update_posted_date": "2024-02-02",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 39,
      "location_summary": "Yuma, Arizona • Fremont, California • Los Angeles, California + 34 more",
      "locations": [
        {
          "city": "Yuma",
          "state": "Arizona"
        },
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Loveland",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03421561"
    },
    {
      "nct_id": "NCT02685098",
      "title": "A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ischemia",
        "Peripheral Arterial Disease",
        "Peripheral Vascular Disease",
        "Vascular Disease",
        "Arterial Occlusive Disease",
        "Arteriosclerosis",
        "Atherosclerosis",
        "Cardiovascular Disease",
        "Pathologic Processes",
        "Orthopedic Procedures",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Allogeneic bone marrow derived mesenchymal stem cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 81,
      "start_date": "2017-01-23",
      "completion_date": "2023-10-03",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02685098"
    },
    {
      "nct_id": "NCT00001313",
      "title": "Evaluation of Patients With Known or Suspected Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Peripheral Artery Disease",
        "Coronary Disease",
        "Diabetes and Heart Failure",
        "Dilated Cardiomyopathy",
        "Heart Failure",
        "Renal Artery Stenosis",
        "Pulmonary Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": null,
      "start_date": "1992-05-10",
      "completion_date": "2009-01-06",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001313"
    },
    {
      "nct_id": "NCT00390767",
      "title": "Safety Study of MultiGeneAngio in Patients With Peripheral Arterial Disease (PAD)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "PAD",
        "Claudication"
      ],
      "interventions": [
        {
          "name": "MultiGeneAngio",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "MultiGene Vascular Systems Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 12,
      "start_date": "2006-10",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2015-03-05",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00390767"
    },
    {
      "nct_id": "NCT00489164",
      "title": "Feasibility Study With the Sirolimus-Eluting BX Velocity Balloon-Expandable Stent in the Treatment of Diabetic Patients With Native Coronary Artery Lesions",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Vascular Diseases"
      ],
      "interventions": [
        {
          "name": "Sirolimus-Eluting BX Velocity Balloon-Expandable Stent",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cordis US Corp.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 83,
      "start_date": "2002-08",
      "completion_date": "2004-05",
      "has_results": false,
      "last_update_posted_date": "2008-11-11",
      "last_synced_at": "2026-10-15T00:26:50.103Z",
      "location_count": 4,
      "location_summary": "La Jolla, California • Orlando, Florida • Boston, Massachusetts + 1 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00489164"
    }
  ]
}