{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Persistent+Postsurgical+Pain&page=2",
    "query": {
      "condition": "Persistent Postsurgical Pain",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Persistent+Postsurgical+Pain&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T06:10:10.887Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01320150",
      "title": "Risk Factors and Mechanisms for Persistent Postsurgical Pain After Total Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Persistent Postsurgical Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 311,
      "start_date": "2011-03",
      "completion_date": "2018-04",
      "has_results": true,
      "last_update_posted_date": "2021-09-23",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01320150"
    },
    {
      "nct_id": "NCT03965897",
      "title": "Preventing Persistent Post-Surgical Pain and Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain",
        "Function",
        "Anxiety",
        "Depression",
        "Arthroplasty, Replacement, Knee",
        "Veterans"
      ],
      "interventions": [
        {
          "name": "Acceptance and Commitment Therapy (ACT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control (AC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 402,
      "start_date": "2019-07-29",
      "completion_date": "2024-01-30",
      "has_results": true,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03965897"
    },
    {
      "nct_id": "NCT05386693",
      "title": "Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hernia, Inguinal",
        "Chronic Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Ilioinguinal nerve block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2022-04-20",
      "completion_date": "2024-03-25",
      "has_results": false,
      "last_update_posted_date": "2024-04-05",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05386693"
    },
    {
      "nct_id": "NCT02437188",
      "title": "Preventing Persistent Post-Surgical Pain and Opioid Use In At-Risk Veterans: Effect of ACT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Persistent Post-surgical Pain",
        "Acceptance and Commitment Therapy",
        "Substance Use Disorder"
      ],
      "interventions": [
        {
          "name": "ACT (Acceptance and Commitment Therapy)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Barbara A Rakel",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 88,
      "start_date": "2015-02",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2019-08-01",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02437188"
    },
    {
      "nct_id": "NCT06466941",
      "title": "Understanding the Acute Pain Phenotype in Patients Undergoing Surgery",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Pain",
        "Chronic Post Operative Pain",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "regional anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "no regional anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "acute pain consultation",
          "type": "OTHER"
        },
        {
          "name": "no acute pain consultation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2024-07-03",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06466941"
    },
    {
      "nct_id": "NCT04019834",
      "title": "Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Breast Cancer",
        "Mastectomy",
        "Anesthesia, Local",
        "Narcotic Use"
      ],
      "interventions": [
        {
          "name": "regional nerve block with local anesthesia of bupivacaine with steroid",
          "type": "DRUG"
        },
        {
          "name": "Placebo regional nerveblock with normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "19 Years and older · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2020-07-06",
      "completion_date": "2021-11-25",
      "has_results": false,
      "last_update_posted_date": "2022-08-03",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04019834"
    },
    {
      "nct_id": "NCT01201668",
      "title": "DPBRN Persistent Pain and Root Canal Therapy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Root Canal Therapy",
        "Persistent Tooth Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dental Practice-Based Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "19 Years to 70 Years"
      },
      "enrollment_count": 500,
      "start_date": "2010-08",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2011-09-20",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 7,
      "location_summary": "Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01201668"
    },
    {
      "nct_id": "NCT04681183",
      "title": "Pilot Study Evaluating Neuro-Imaging Correlates of Epigenetic Finding in Prediction of Chronic Postsurgical Pain",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Post-surgical Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2020-12-14",
      "completion_date": "2024-12-01",
      "has_results": false,
      "last_update_posted_date": "2024-03-13",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04681183"
    },
    {
      "nct_id": "NCT04637802",
      "title": "Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Juvenile; Scoliosis",
        "Scoliosis Idiopathic",
        "Scoliosis; Adolescence",
        "Scoliosis;Congenital",
        "Kyphosis",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "CBT (SurgeryPal)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 433,
      "start_date": "2020-12-29",
      "completion_date": "2025-03-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04637802"
    },
    {
      "nct_id": "NCT01731873",
      "title": "Patient Controlled Analgesia Pharmacogenetic Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 182,
      "start_date": "2012-01-17",
      "completion_date": "2019-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-09-03",
      "last_synced_at": "2026-06-26T06:10:10.887Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01731873"
    }
  ]
}