{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Phantom+Limb+Pain+After+Amputation",
    "query": {
      "condition": "Phantom Limb Pain After Amputation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Phantom+Limb+Pain+After+Amputation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T02:12:46.759Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03484429",
      "title": "Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Phantom Limb Pain",
        "Postoperative Pain",
        "Neuroma",
        "Acute Pain",
        "Chronic Pain",
        "Residual Limbs",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Peripheral nerve stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Standard Medical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Hunter Holmes Mcguire Veteran Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2017-12-01",
      "completion_date": "2021-04-17",
      "has_results": true,
      "last_update_posted_date": "2021-07-21",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03484429"
    },
    {
      "nct_id": "NCT05915065",
      "title": "VR to Evaluate Phantom Limb Pain",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Phantom Limb Pain",
        "Phantom Pain",
        "Phantom Sensation",
        "Phantom Limb Syndrome With Pain",
        "Phantom Pain Following Amputation of Lower Limb",
        "Phantom Pain Following Amputation of Upper Limb",
        "Amputation",
        "Upper Limb Amputation at the Hand",
        "Upper Limb Amputation at the Wrist",
        "Upper Limb Amputation Below Elbow (Injury)",
        "Upper Limb Amputation Above Elbow (Injury)",
        "Lower Limb Amputation Knee",
        "Lower Limb Amputation Above Knee (Injury)",
        "Lower Limb Amputation Below Knee (Injury)",
        "Lower Limb Amputation at Ankle (Injury)"
      ],
      "interventions": [
        {
          "name": "Coapt Phantom Limb Pain Management System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2020-10-01",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-14",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05915065"
    },
    {
      "nct_id": "NCT06071715",
      "title": "Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation, Surgical",
        "Amputation, Traumatic",
        "Phantom Limb Pain",
        "Phantom Pain Following Amputation of Lower Limb"
      ],
      "interventions": [
        {
          "name": "ACTIVE cryoneurolysis",
          "type": "DEVICE"
        },
        {
          "name": "SHAM cryoneurolysis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2024-02-12",
      "completion_date": "2025-10-09",
      "has_results": true,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06071715"
    },
    {
      "nct_id": "NCT03461120",
      "title": "Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lower Extremity Surgical Amputation",
        "Post-amputation Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Experimental continuous peripheral nerve blocks",
          "type": "DRUG"
        },
        {
          "name": "Control continuous peripheral nerve blocks",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 203,
      "start_date": "2018-03-23",
      "completion_date": "2026-11-18",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 8,
      "location_summary": "San Diego, California • Boston, Massachusetts • Cleveland, Ohio + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03461120"
    },
    {
      "nct_id": "NCT04751526",
      "title": "A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 3)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Management"
      ],
      "interventions": [
        {
          "name": "BreEStim 240",
          "type": "DEVICE"
        },
        {
          "name": "EStim 240",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 18,
      "start_date": "2021-04-02",
      "completion_date": "2024-02-22",
      "has_results": true,
      "last_update_posted_date": "2025-03-20",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04751526"
    },
    {
      "nct_id": "NCT04750538",
      "title": "A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Management"
      ],
      "interventions": [
        {
          "name": "BreEStim 120",
          "type": "DEVICE"
        },
        {
          "name": "BreEStim 240",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 17,
      "start_date": "2021-04-02",
      "completion_date": "2023-05-19",
      "has_results": true,
      "last_update_posted_date": "2025-03-20",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04750538"
    },
    {
      "nct_id": "NCT03449667",
      "title": "Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Amputation Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Cryoneurolysis",
          "type": "DEVICE"
        },
        {
          "name": "Sham Comparator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2018-03-23",
      "completion_date": "2022-03-17",
      "has_results": true,
      "last_update_posted_date": "2023-02-17",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 6,
      "location_summary": "Palo Alto, California • San Diego, California • Gainesville, Florida + 2 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03449667"
    },
    {
      "nct_id": "NCT01003704",
      "title": "Incidence of Phantom Limb Pain and Method of Anesthesia After Lower Extremity Amputation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Lower extremity amputation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "North Texas Veterans Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2009-10-29",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01003704"
    },
    {
      "nct_id": "NCT05880251",
      "title": "Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Phantom Limb Pain After Amputation",
        "Lower Limb Amputation",
        "Upper Limb Amputation",
        "Phantom Pain",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Operant Conditioning with Peripheral Stimulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Group with Peripheral Stimulation Only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2023-07-01",
      "completion_date": "2025-08-29",
      "has_results": false,
      "last_update_posted_date": "2026-01-16",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05880251"
    },
    {
      "nct_id": "NCT06956508",
      "title": "Prophylactic TBR on Phantom Limb Pain",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Phantom Limb Pain After Amputation"
      ],
      "interventions": [
        {
          "name": "Targeted Brain Rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "OrthoCarolina Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2026-02-05",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-05-22T02:12:46.759Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06956508"
    }
  ]
}