{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Photodamaged+Skin",
    "query": {
      "condition": "Photodamaged Skin"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Photodamaged+Skin&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:39:25.011Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00113100",
      "title": "Mechanisms of Skin Repair by Topical Estrogen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Wrinkling"
      ],
      "interventions": [
        {
          "name": "Topical 17-beta estradiol in ethanol/propylene glycol (ETOH/PG)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 152,
      "start_date": "2004-08",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2015-05-21",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00113100"
    },
    {
      "nct_id": "NCT05423873",
      "title": "A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperpigmentation",
        "Photodamaged Skin",
        "Wrinkle",
        "Fine Lines"
      ],
      "interventions": [
        {
          "name": "Gentle Cleansing Lotion, Revision Skincare",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 33,
      "start_date": "2021-03-17",
      "completion_date": "2022-02-10",
      "has_results": false,
      "last_update_posted_date": "2022-06-21",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 3,
      "location_summary": "Solana Beach, California • Greenwood Village, Colorado • Nashville, Tennessee",
      "locations": [
        {
          "city": "Solana Beach",
          "state": "California"
        },
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05423873"
    },
    {
      "nct_id": "NCT01787461",
      "title": "A Study to Assess the Effects of an Oral Dietary Supplement on Overall Facial Appearance Among Healthy Adult Women With Existing Skin Damage From Sun Exposure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Photodamaged Skin"
      ],
      "interventions": [
        {
          "name": "Imedeen",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 65 Years · Female only"
      },
      "enrollment_count": 194,
      "start_date": "2013-01",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2015-03-18",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 4,
      "location_summary": "Miami, Florida • Fair Lawn, New Jersey • Lynchburg, Virginia + 1 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Fair Lawn",
          "state": "New Jersey"
        },
        {
          "city": "Lynchburg",
          "state": "Virginia"
        },
        {
          "city": "Virginia Beach",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01787461"
    },
    {
      "nct_id": "NCT04065035",
      "title": "A Clinical Study to Evaluate Efficacy and Tolerability of a Cosmetic Product for Arm Firming",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Photodamaged Skin",
        "Skin Care"
      ],
      "interventions": [
        {
          "name": "Topical Body Firming Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Body Cleanser",
          "type": "OTHER"
        },
        {
          "name": "Sunscreen",
          "type": "OTHER"
        },
        {
          "name": "Placebo Moisturizer",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 46,
      "start_date": "2018-12-13",
      "completion_date": "2019-07-17",
      "has_results": false,
      "last_update_posted_date": "2019-08-22",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 1,
      "location_summary": "Richardson, Texas",
      "locations": [
        {
          "city": "Richardson",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04065035"
    },
    {
      "nct_id": "NCT04523961",
      "title": "Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia, Local",
        "Photodamaged Skin",
        "Topical and Infiltration Anesthetic Toxicity"
      ],
      "interventions": [
        {
          "name": "2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion",
          "type": "DRUG"
        },
        {
          "name": "7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2021-01-08",
      "completion_date": "2025-02-19",
      "has_results": true,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04523961"
    },
    {
      "nct_id": "NCT07222397",
      "title": "2910 nm Erbium-Doped Fluoride Fiber Glass Laser for the Treatment of Advanced Perioral Lines and Wrinkles",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Photodamaged Skin",
        "Rhytids",
        "Lines Skin",
        "Wrinkles and Rhytides"
      ],
      "interventions": [
        {
          "name": "Laser Resurfacing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "FA Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-03-01",
      "completion_date": "2026-02",
      "has_results": false,
      "last_update_posted_date": "2025-10-29",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07222397"
    },
    {
      "nct_id": "NCT02889159",
      "title": "Immunologic Profile of Chronically Photodamaged Skin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Photoaged Skin",
        "Normal Skin"
      ],
      "interventions": [
        {
          "name": "Candida albicans antigen",
          "type": "BIOLOGICAL"
        },
        {
          "name": "histamine phosphate",
          "type": "BIOLOGICAL"
        },
        {
          "name": "imiquimod 5% cream",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Tape Stripping",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2016-06-06",
      "completion_date": "2023-02-23",
      "has_results": false,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02889159"
    },
    {
      "nct_id": "NCT01283464",
      "title": "Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Photodamaged Skin",
        "Wrinkles"
      ],
      "interventions": [
        {
          "name": "Retinol",
          "type": "DRUG"
        },
        {
          "name": "Tretinoin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2010-11",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2016-04-04",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01283464"
    },
    {
      "nct_id": "NCT04096742",
      "title": "Altreno for Chest Rejuvenation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Photodamaged Skin",
        "Photoaging"
      ],
      "interventions": [
        {
          "name": "tretinoin 0.05% lotion (Altreno)",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Goldman, Butterwick, Fitzpatrick and Groff",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2019-08-06",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-04-02",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04096742"
    },
    {
      "nct_id": "NCT06351358",
      "title": "Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Photoaging",
        "Weight Loss",
        "Skin Laxity",
        "Photodamaged Skin",
        "Volume Deficiency of the Midface"
      ],
      "interventions": [
        {
          "name": "Sculptra treatment",
          "type": "DEVICE"
        },
        {
          "name": "Restylane Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 41,
      "start_date": "2024-02-19",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-05-22T05:39:25.011Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • New York, New York",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06351358"
    }
  ]
}