{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Physical+Discomfort", "query": { "condition": "Physical Discomfort" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 14, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Physical+Discomfort&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-10T21:41:26.576Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05649384", "title": "Emergency Department Triage of Patients With Acute Chest Pain Based on the ESC 0/1-hour Algorithm (PRESC1SE-MI)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Chest Pain", "NSTEMI - Non-ST Segment Elevation MI" ], "interventions": [ { "name": "European Society of Cardiology hs-cTnT/I 0 h/1 h algorithm", "type": "DIAGNOSTIC_TEST" }, { "name": "European Society of Cardiology hs-cTnT/I 0 h/3 h algorithm", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "University Hospital, Basel, Switzerland", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 64374, "start_date": "2020-12-01", "completion_date": "2028-05-31", "has_results": false, "last_update_posted_date": "2026-01-27", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05649384" }, { "nct_id": "NCT01027611", "title": "Patient Assessment of Topical Anesthetic Effectiveness for Intravitreal Injections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain" ], "interventions": [ { "name": "proparacaine HCL 0.5%", "type": "DRUG" }, { "name": "proparacaine HCL 0.5% + 4% lidocaine solution", "type": "DRUG" }, { "name": "3.5% viscous lidocaine gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Illinois Retina Associates", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 120, "start_date": "2009-10", "completion_date": "2009-12", "has_results": false, "last_update_posted_date": "2010-05-04", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 1, "location_summary": "Joliet, Illinois", "locations": [ { "city": "Joliet", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01027611" }, { "nct_id": "NCT00385684", "title": "Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Alzheimer Disease", "Dementia", "Dementia, Vascular", "Pain" ], "interventions": [ { "name": "hydrocodone/APAP w placebo PRN", "type": "DRUG" }, { "name": "hydrocodone/APAP", "type": "DRUG" }, { "name": "placebo with hydrocodone/APAP PRN", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": null, "sex": "ALL", "summary": "55 Years and older" }, "enrollment_count": 11, "start_date": "2007-10", "completion_date": "2014-06", "has_results": true, "last_update_posted_date": "2015-11-20", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 3, "location_summary": "Tuscaloosa, Alabama", "locations": [ { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00385684" }, { "nct_id": "NCT01313754", "title": "Comparison of Skin Incision Closure Material for the Transobturator Suburethral Sling Procedure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pain, Postoperative", "Irritation (Physical)", "Pelvic Pain" ], "interventions": [ { "name": "Vicryl Suture", "type": "PROCEDURE" }, { "name": "Dermabond", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Loma Linda University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 160, "start_date": "2011-05", "completion_date": "2012-12", "has_results": false, "last_update_posted_date": "2013-01-31", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 1, "location_summary": "Loma Linda, California", "locations": [ { "city": "Loma Linda", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01313754" }, { "nct_id": "NCT04115917", "title": "Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Retina--Diseases", "Retinal Detachment", "Retinal Degeneration" ], "interventions": [ { "name": "Schocket scleral depressor", "type": "DEVICE" }, { "name": "Cotton tipped applicator", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "New York City Health and Hospitals Corporation", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 87, "start_date": "2018-01-01", "completion_date": "2019-01-31", "has_results": false, "last_update_posted_date": "2019-10-04", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 1, "location_summary": "Brooklyn, New York", "locations": [ { "city": "Brooklyn", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04115917" }, { "nct_id": "NCT02157701", "title": "Polyherbal Capsule Formulation for Joint Health", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Knee Discomfort", "Pain Physical Activity" ], "interventions": [ { "name": "Polyherbal capsule", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo capsule", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "NewChapter, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "25 Years to 75 Years" }, "enrollment_count": 108, "start_date": "2014-06", "completion_date": "2015-04", "has_results": false, "last_update_posted_date": "2015-10-14", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 5, "location_summary": "Homestead, Florida • Duncansville, Pennsylvania • Dallas, Texas + 2 more", "locations": [ { "city": "Homestead", "state": "Florida" }, { "city": "Duncansville", "state": "Pennsylvania" }, { "city": "Dallas", "state": "Texas" }, { "city": "San Angelo", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02157701" }, { "nct_id": "NCT06227676", "title": "Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Dysmenorrhea Primary", "Dysmenorrhea", "Menstrual Discomfort", "Menstrual Problem", "Menstrual Cycle Abnormal", "Menstrual Pain", "Period Pain", "Period Problem", "PMS", "Premenstrual Syndrome", "PCOS", "PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries", "PCOS (Polycystic Ovary Syndrome) of Left Ovary", "PCOS (Polycystic Ovary Syndrome) of Right Ovary", "Polycystic Ovary Syndrome", "Premenstrual Dysphoric Disorder", "Cramps", "Ovarian Cysts" ], "interventions": [ { "name": "Cramp Bites by Aunt Flo's Kitchen", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "25 Years", "sex": "FEMALE", "summary": "18 Years to 25 Years · Female only" }, "enrollment_count": 12, "start_date": "2022-07-21", "completion_date": "2022-10-31", "has_results": false, "last_update_posted_date": "2024-04-12", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 1, "location_summary": "Ithaca, New York", "locations": [ { "city": "Ithaca", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06227676" }, { "nct_id": "NCT07502092", "title": "Mindfulness in Motion Targeted to Sustaining the Mental and Physical Resilience of First Responders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stress", "Resilience and Mental Health of First Responders", "Work Engagement", "Musculoskeletal Discomfort", "First Responders" ], "interventions": [ { "name": "Mindfulness in Motion for First Responders", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 29, "start_date": "2023-08-01", "completion_date": "2025-12-01", "has_results": false, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07502092" }, { "nct_id": "NCT04083053", "title": "High-Resolution Anoscopy Perceived Discomfort Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pain", "Anal Cancer" ], "interventions": [ { "name": "Perianal Exam", "type": "PROCEDURE" }, { "name": "high-resolution anoscopy (HRA) with biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 54, "start_date": "2019-09-17", "completion_date": "2021-01-15", "has_results": false, "last_update_posted_date": "2021-01-28", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04083053" }, { "nct_id": "NCT06112106", "title": "The Effect of Intelligent Exercise and Ergonomic Recommendations on Surgeon Musculoskeletal Discomfort", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Occupational Injuries", "Occupational Exposure" ], "interventions": [ { "name": "Intelligent Physical Exercise Training (IPET)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Aarhus", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2023-12-13", "completion_date": "2026-05-05", "has_results": false, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-06-10T21:41:26.576Z", "location_count": 2, "location_summary": "Ann Arbor, Michigan • Rochester, Minnesota", "locations": [ { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT06112106" } ] }