{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Physiological+Effect+of+Drugs&page=4", "query": { "condition": "Physiological Effect of Drugs", "page": 4 }, "page_size": 10 }, "pagination": { "page": 4, "page_size": 10, "total_count": 173, "total_pages": 18, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Physiological+Effect+of+Drugs&page=5&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Physiological+Effect+of+Drugs&page=3&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-06T09:37:40.448Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06740812", "title": "Broadening Antiemetics Research by Comparing the Effectiveness of Fosaprepitant and Metoclopramide", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Nausea and Vomiting", "Nausea", "Vomiting" ], "interventions": [ { "name": "Fosaprepitant for Injection", "type": "DRUG" }, { "name": "Metoclopramide Injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 212, "start_date": "2026-12", "completion_date": "2027-09", "has_results": false, "last_update_posted_date": "2026-06-29", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06740812" }, { "nct_id": "NCT02864953", "title": "Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Brain Edema", "Stroke, Acute" ], "interventions": [ { "name": "BIIB093", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Remedy Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 535, "start_date": "2018-08-29", "completion_date": "2023-08-18", "has_results": true, "last_update_posted_date": "2024-11-25", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 74, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Palo Alto, California + 59 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Palo Alto", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02864953" }, { "nct_id": "NCT05288166", "title": "A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Prostatic Neoplasms", "Neoplasm Metastasis", "Urogenital Neoplasms", "Physiological Effects of Drugs", "Antineoplastic Agents", "Antineoplastic Agents, Hormonal", "Androgens", "Hormones", "Hormones, Hormone Substitutes, and Hormone Antagonists", "Abiraterone Acetate", "Steroid Synthesis Inhibitors", "Cytochrome P-450", "Enzyme Inhibitors", "Prednisone", "Prednisolone", "Cyclin-Dependent Kinase 4", "Cyclin-Dependent Kinase 6" ], "interventions": [ { "name": "Abemaciclib", "type": "DRUG" }, { "name": "Abiraterone", "type": "DRUG" }, { "name": "Prednisone or Prednisolone", "type": "DRUG" }, { "name": "Placebo for Abemaciclib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 925, "start_date": "2022-04-14", "completion_date": "2027-10", "has_results": true, "last_update_posted_date": "2026-07-01", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 63, "location_summary": "Prescott, Arizona • Prescott Valley, Arizona • Tucson, Arizona + 57 more", "locations": [ { "city": "Prescott", "state": "Arizona" }, { "city": "Prescott Valley", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Jonesboro", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05288166" }, { "nct_id": "NCT05407636", "title": "Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "AMD", "nAMD", "Wet Age-related Macular Degeneration", "wAMD", "WetAMD", "CNV" ], "interventions": [ { "name": "ABBV-RGX-314 Dose 1", "type": "GENETIC" }, { "name": "ABBV-RGX-314 Dose 2", "type": "GENETIC" }, { "name": "Aflibercept (EYLEA®)", "type": "BIOLOGICAL" } ], "intervention_types": [ "GENETIC", "BIOLOGICAL" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "50 Years to 89 Years" }, "enrollment_count": 735, "start_date": "2022-01-13", "completion_date": "2027-11", "has_results": false, "last_update_posted_date": "2026-08-03", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 107, "location_summary": "Phoenix, Arizona • Scottsdale, Arizona • Bakersfield, California + 94 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Beverly Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05407636" }, { "nct_id": "NCT04708886", "title": "Romosozumab in Women With Chronic SCI", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Osteoporosis", "Bone Loss", "Osteopenia, Osteoporosis", "Spinal Cord Injuries", "Chronic Spinal Paralysis" ], "interventions": [ { "name": "Romosozumab", "type": "DRUG" }, { "name": "Alendronate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 12, "start_date": "2021-03-01", "completion_date": "2024-06-10", "has_results": true, "last_update_posted_date": "2025-09-24", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04708886" }, { "nct_id": "NCT05887375", "title": "Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Spine Surgery", "Reversal of Neuromuscular Blockade", "Urinary Retention Postoperative" ], "interventions": [ { "name": "Sugammadex", "type": "DRUG" }, { "name": "Neostigmine", "type": "DRUG" }, { "name": "Glycopyrrolate", "type": "DRUG" }, { "name": "Rocuronium", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Missouri-Columbia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 118, "start_date": "2023-08-03", "completion_date": "2026-01-15", "has_results": false, "last_update_posted_date": "2026-05-05", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05887375" }, { "nct_id": "NCT05103618", "title": "Effect of Meditation and Controls and Subjects With Parkinson's Disease on Brain Activity Measured by fMRI With FDOPA", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Parkinson Disease", "Idiopathic Parkinson Disease" ], "interventions": [ { "name": "[F-18] Fluorodopa Positron Emission Tomography", "type": "DRUG" }, { "name": "OM Meditation", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Andrew Newberg", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": null, "sex": "ALL", "summary": "25 Years and older" }, "enrollment_count": 0, "start_date": "2021-07-08", "completion_date": "2025-07-21", "has_results": false, "last_update_posted_date": "2025-09-19", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05103618" }, { "nct_id": "NCT05217641", "title": "A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult Participants", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "BG505 MD39.3 mRNA", "type": "BIOLOGICAL" }, { "name": "BG505 MD39.3 gp151 mRNA", "type": "BIOLOGICAL" }, { "name": "BG505 MD39.3 gp151 CD4KO mRNA", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 108, "start_date": "2022-02-11", "completion_date": "2027-06-24", "has_results": true, "last_update_posted_date": "2025-10-14", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 10, "location_summary": "Birmingham, Alabama • Los Angeles, California • Boston, Massachusetts + 5 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05217641" }, { "nct_id": "NCT01579513", "title": "Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Congenital Heart Disease", "Disorder of Fetus or Newborn" ], "interventions": [ { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "30 Days", "sex": "ALL", "summary": "Up to 30 Days" }, "enrollment_count": 190, "start_date": "2012-06", "completion_date": "2018-12-19", "has_results": true, "last_update_posted_date": "2019-12-09", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 2, "location_summary": "Atlanta, Georgia • Charleston, South Carolina", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01579513" }, { "nct_id": "NCT04178993", "title": "Behavioral Effects of Drugs (Inpatient): 40 [Methamphetamine, Methylphenidate, Duloxetine]", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Methamphetamine Use Disorder" ], "interventions": [ { "name": "Methamphetamine", "type": "DRUG" }, { "name": "Methylphenidate", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Craig Rush", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 8, "start_date": "2019-09-01", "completion_date": "2021-05-05", "has_results": true, "last_update_posted_date": "2023-01-09", "last_synced_at": "2026-10-06T09:37:40.448Z", "location_count": 2, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" }, { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT04178993" } ] }