{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pick%27s+Disease&page=5", "query": { "condition": "Pick's Disease", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 239, "total_pages": 24, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pick%27s+Disease&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pick%27s+Disease&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-11T16:58:35.637Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04720001", "title": "Florbetaben PET Imaging in PPA", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Primary Progressive Aphasia", "Alzheimer Disease" ], "interventions": [ { "name": "Florbetaben F18", "type": "DRUG" }, { "name": "PET", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 1, "start_date": "2018-08-23", "completion_date": "2021-02-26", "has_results": false, "last_update_posted_date": "2024-10-16", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04720001" }, { "nct_id": "NCT07054515", "title": "A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Niemann-Pick Type C Disease", "GM1 Gangliosidosis", "GM2 Gangliosidosis" ], "interventions": [ { "name": "AZ-3102", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Azafaros B.V.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": null, "sex": "ALL", "summary": "4 Years and older" }, "enrollment_count": 147, "start_date": "2025-06-30", "completion_date": "2028-06-14", "has_results": false, "last_update_posted_date": "2026-09-24", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 5, "location_summary": "Oakland, California • Minneapolis, Minnesota • Rochester, Minnesota + 2 more", "locations": [ { "city": "Oakland", "state": "California" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Rochester", "state": "Minnesota" }, { "city": "Dallas", "state": "Texas" }, { "city": "Fairfax", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07054515" }, { "nct_id": "NCT04425148", "title": "Gamma-Induction in FrontoTemporal Dementia Trial", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Frontotemporal Dementia" ], "interventions": [ { "name": "Transcranial Alternating Current Stimulation (tACS)", "type": "DEVICE" }, { "name": "Sham Transcranial Alternating Current Stimulation (sham tACS)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "40 Years to 85 Years" }, "enrollment_count": 70, "start_date": "2020-12-30", "completion_date": "2025-12", "has_results": false, "last_update_posted_date": "2024-09-26", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04425148" }, { "nct_id": "NCT00537004", "title": "Language in Primary Progressive Aphasia", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Primary Progressive Aphasia" ], "interventions": [], "intervention_types": [], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 500, "start_date": "2007-05", "completion_date": "2027-04", "has_results": false, "last_update_posted_date": "2026-02-27", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00537004" }, { "nct_id": "NCT04157244", "title": "The Music, Sleep and Dementia Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dementia", "Alzheimer Disease", "Circadian Rhythm Disorders", "Circadian Rhythm Sleep Disorder", "Insomnia", "Hypersomnia", "Cognitive Impairment", "Cognitive Decline", "Mild Cognitive Impairment", "Frontotemporal Dementia", "Neurocognitive Disorders", "Vascular Dementia", "Sleep Disorder", "Memory Impairment" ], "interventions": [ { "name": "Tailored music listening intervention", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "110 Years", "sex": "ALL", "summary": "18 Years to 110 Years" }, "enrollment_count": 32, "start_date": "2019-03-12", "completion_date": "2021-01-12", "has_results": false, "last_update_posted_date": "2021-01-13", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04157244" }, { "nct_id": "NCT03682185", "title": "The Healthy Patterns Sleep Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dementia", "Alzheimer Disease", "Circadian Rhythm Disorders", "Circadian Rhythm Sleep Disorder", "Insomnia", "Hypersomnia", "Cognitive Impairment", "Cognitive Decline", "Mild Cognitive Impairment", "Frontotemporal Dementia", "Neurocognitive Disorders", "Vascular Dementia", "Sleep Disorder", "Memory Impairment" ], "interventions": [ { "name": "Attention-Control Condition", "type": "BEHAVIORAL" }, { "name": "Timed Activity Intervention", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "110 Years", "sex": "ALL", "summary": "18 Years to 110 Years" }, "enrollment_count": 421, "start_date": "2016-05-01", "completion_date": "2021-05-31", "has_results": true, "last_update_posted_date": "2024-07-26", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03682185" }, { "nct_id": "NCT04881617", "title": "Treatment for Speech and Language in Primary Progressive Aphasia", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Primary Progressive Aphasia", "Semantic Dementia", "Semantic Memory Disorder", "Logopenic Progressive Aphasia", "Nonfluent Aphasia, Progressive", "Aphasia", "Aphasia, Progressive" ], "interventions": [ { "name": "Lexical Retrieval Training (LRT)", "type": "BEHAVIORAL" }, { "name": "Video-Implemented Script Training for Aphasia (VISTA)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Texas at Austin", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 60, "start_date": "2017-07-01", "completion_date": "2025-12-30", "has_results": false, "last_update_posted_date": "2025-11-13", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 2, "location_summary": "San Francisco, California • Austin, Texas", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04881617" }, { "nct_id": "NCT05642221", "title": "Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Juvenile Neuronal Ceroid Lipofuscinosis", "Smith-Lemli-Opitz Syndrome", "Creatine Transporter Deficiency", "Niemann-Pick Disease Type C1" ], "interventions": [], "intervention_types": [], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "110 Years", "sex": "ALL", "summary": "6 Months to 110 Years" }, "enrollment_count": 73, "start_date": "2023-01-23", "completion_date": "2025-04-25", "has_results": false, "last_update_posted_date": "2026-10-08", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05642221" }, { "nct_id": "NCT02254863", "title": "UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adrenoleukodystrophy", "Batten Disease", "Mucopolysaccharidosis II", "Leukodystrophy, Globoid Cell", "Leukodystrophy, Metachromatic", "Neimann Pick Disease", "Pelizaeus-Merzbacher Disease", "Sandhoff Disease", "Tay-Sachs Disease", "Brain Diseases, Metabolic, Inborn", "Alpha-Mannosidosis", "Sanfilippo Mucopolysaccharidoses" ], "interventions": [ { "name": "DUOC-01", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Joanne Kurtzberg, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Week", "maximum_age": "22 Years", "sex": "ALL", "summary": "1 Week to 22 Years" }, "enrollment_count": 40, "start_date": "2014-09", "completion_date": "2027-10", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02254863" }, { "nct_id": "NCT01372228", "title": "Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Hurler Syndrome (MPS I)", "Hurler-Scheie Syndrome", "Hunter Syndrome (MPS II)", "Sanfilippo Syndrome (MPS III)", "Krabbe Disease (Globoid Leukodystrophy)", "Metachromatic Leukodystrophy (MLD)", "Adrenoleukodystrophy (ALD and AMN)", "Sandhoff Disease", "Tay Sachs Disease", "Pelizaeus Merzbacher (PMD)", "Niemann-Pick Disease", "Alpha-mannosidosis" ], "interventions": [ { "name": "hematopoietic stem cell infusion", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Talaris Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 3, "start_date": "2011-04", "completion_date": "2016-04", "has_results": false, "last_update_posted_date": "2023-04-12", "last_synced_at": "2026-10-11T16:58:35.637Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01372228" } ] }