{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pit-and-Fissure+Sealants",
    "query": {
      "condition": "Pit-and-Fissure Sealants"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T07:54:39.737Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02668874",
      "title": "A Clinical Trial Comparing Isolite® vs. Cotton Roll Isolation in the Placement of Dental Sealants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries on Pit and Fissure Surface"
      ],
      "interventions": [
        {
          "name": "Isolite System",
          "type": "DEVICE"
        },
        {
          "name": "Cotton Roll Technique",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "6 Years to 16 Years"
      },
      "enrollment_count": 104,
      "start_date": "2015-02",
      "completion_date": "2017-08-21",
      "has_results": true,
      "last_update_posted_date": "2022-02-01",
      "last_synced_at": "2026-06-11T07:54:39.737Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02668874"
    },
    {
      "nct_id": "NCT03886727",
      "title": "Effectiveness of Rubber Dam Isolation Versus Cotton Roll Isolation on Bonded Fissure Sealant Retention",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries in Children",
        "Dental Caries on Pit and Fissure Surface",
        "Dental Leakage"
      ],
      "interventions": [
        {
          "name": "Rubber Dam Set",
          "type": "DEVICE"
        },
        {
          "name": "Dental Cotton Roll",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zafer Cavit Cehreli, DDS, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "6 Years to 16 Years"
      },
      "enrollment_count": 50,
      "start_date": "2020-02-01",
      "completion_date": "2021-06-01",
      "has_results": false,
      "last_update_posted_date": "2019-11-05",
      "last_synced_at": "2026-06-11T07:54:39.737Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03886727"
    },
    {
      "nct_id": "NCT04682730",
      "title": "An Implementation Strategy for the Adoption of an Evidence-Based Guideline for Pit-and-Fissure Sealants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pit-and-Fissure Sealants"
      ],
      "interventions": [
        {
          "name": "Deliberative Loop",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 896,
      "start_date": "2021-01-01",
      "completion_date": "2022-01-26",
      "has_results": true,
      "last_update_posted_date": "2023-07-12",
      "last_synced_at": "2026-06-11T07:54:39.737Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04682730"
    }
  ]
}