{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Platelet+Rich+Fibrin&page=2",
    "query": {
      "condition": "Platelet Rich Fibrin",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Platelet+Rich+Fibrin&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T02:05:27.336Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06810726",
      "title": "Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Type 1 Diabetes Mellitus",
        "Type 2 Diabetes Mellitus (T2DM)",
        "Neuroischemic Foot Ulcer",
        "Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)",
        "Chronic Wound Care"
      ],
      "interventions": [
        {
          "name": "Platelet Rich Plasma",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Estar Medical dba Medical Technologies, LTD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-04-15",
      "completion_date": "2026-08-15",
      "has_results": false,
      "last_update_posted_date": "2025-06-12",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 2,
      "location_summary": "Corpus Christi, Texas",
      "locations": [
        {
          "city": "Corpus Christi",
          "state": "Texas"
        },
        {
          "city": "Corpus Christi",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06810726"
    },
    {
      "nct_id": "NCT04706182",
      "title": "Platelet-rich Fibrin and Grooving for Sagittal Split Osteotomy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inferior Alveolar Nerve Injury",
        "Nerve Injury",
        "Neurosensory Disorder",
        "Mandibular Nerve Injury"
      ],
      "interventions": [
        {
          "name": "Platelet-rich fibrin (PRF)",
          "type": "PROCEDURE"
        },
        {
          "name": "Proximal segment grooving (PSG)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jesse Han",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 88,
      "start_date": "2021-02-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-01-12",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04706182"
    },
    {
      "nct_id": "NCT00198185",
      "title": "Cascade PRFM Study: The Evaluation of Cascade Platelet-Rich Fibrin Matrix (PRFM) on Rotator Cuff Healing",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Rotator Cuff",
        "Tendon Injuries"
      ],
      "interventions": [
        {
          "name": "Placement of Platelet Rich Fibrin Matrix During Arthroscopic Rotator Cuff Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2005-01",
      "completion_date": "2005-01",
      "has_results": false,
      "last_update_posted_date": "2018-01-04",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00198185"
    },
    {
      "nct_id": "NCT03487718",
      "title": "A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alveolar Ridge Preservation",
        "Tooth Extraction"
      ],
      "interventions": [
        {
          "name": "Leukocyte platelet rich fibrin plug + d-PTFE membrane",
          "type": "BIOLOGICAL"
        },
        {
          "name": "d-PTFE membrane",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "Firas Al Yafi",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 27,
      "start_date": "2018-03-26",
      "completion_date": "2020-06-30",
      "has_results": true,
      "last_update_posted_date": "2021-05-24",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03487718"
    },
    {
      "nct_id": "NCT02154906",
      "title": "Clinical and Radiographic Evaluation of Demineralized Freeze-Dried Bone Allograft Versus Platelet Rich Fibrin for the Treatment of Periodontal Intrabony Defects in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "DFDBA",
          "type": "DEVICE"
        },
        {
          "name": "autologous platelet rich fibrin",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 44,
      "start_date": "2013-11",
      "completion_date": "2016-04",
      "has_results": true,
      "last_update_posted_date": "2016-07-01",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02154906"
    },
    {
      "nct_id": "NCT02312596",
      "title": "A Prospective, Randomized Clinical Trial of PRP Concepts Fibrin Bio-Matrix in Non-Healing Diabetic Foot Ulcers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "PRP Concepts Fibrin Bio-Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Usual and Customary Practice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "PRP Concepts, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2021-01-01",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-04-13",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02312596"
    },
    {
      "nct_id": "NCT04023474",
      "title": "Platelet-Rich Fibrin in the Healing of Regional and Free Flaps",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Head and Neck Disorder",
        "Free Flap"
      ],
      "interventions": [
        {
          "name": "Platelet Rich Fibrin (PRF) Application",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 3,
      "start_date": "2019-12-16",
      "completion_date": "2020-09-10",
      "has_results": false,
      "last_update_posted_date": "2020-09-30",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04023474"
    },
    {
      "nct_id": "NCT07437209",
      "title": "PRF + Minocycline vs Arestin in Non-surgical Perio Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Non-surgical Periodontal Therapy"
      ],
      "interventions": [
        {
          "name": "Arestin",
          "type": "DRUG"
        },
        {
          "name": "PRF + M",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "Center for Advanced Rejuvenation and Esthetics",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 15,
      "start_date": "2024-12-01",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-28",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "Sarasota, Florida",
      "locations": [
        {
          "city": "Sarasota",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07437209"
    },
    {
      "nct_id": "NCT01424969",
      "title": "The Effects of Platelet Rich Plasma on the Integrity of Rotator Cuff Repair",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rotator Cuff Tear Arthropathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2008-08",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2014-02-14",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01424969"
    },
    {
      "nct_id": "NCT07359131",
      "title": "Postoperative Assessment of Platelet-Rich Plasma and Platelet-Rich Fibrin in Temporomandibular Joint Surgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Temporomandibular Joint Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Jingping Wang, MD, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 700,
      "start_date": "2026-11-15",
      "completion_date": "2027-12-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-06-27T02:05:27.336Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07359131"
    }
  ]
}