{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pleuropulmonary+Blastoma",
    "query": {
      "condition": "Pleuropulmonary Blastoma"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T23:41:03.272Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01247597",
      "title": "DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pleuropulmonary Blastoma",
        "Cystic Nephroma",
        "Ovarian Sertoli-Leydig Cell Tumors",
        "Ocular Medulloepithelioma",
        "Nasal Chondromesenchymal Hamartoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "1 Month to 99 Years"
      },
      "enrollment_count": 1500,
      "start_date": "2011-02-13",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-05-21T23:41:03.272Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Rockville, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01247597"
    },
    {
      "nct_id": "NCT02452554",
      "title": "Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pleuropulmonary Blastoma",
        "Recurrent Malignant Peripheral Nerve Sheath Tumor",
        "Recurrent Neuroblastoma",
        "Recurrent Rhabdomyosarcoma",
        "Recurrent Synovial Sarcoma",
        "Wilms Tumor"
      ],
      "interventions": [
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Lorvotuzumab Mertansine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pharmacological Study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BIOLOGICAL"
      ],
      "sponsor": "Children's Oncology Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "12 Months to 30 Years"
      },
      "enrollment_count": 62,
      "start_date": "2015-10-12",
      "completion_date": "2021-09-30",
      "has_results": true,
      "last_update_posted_date": "2022-01-13",
      "last_synced_at": "2026-05-21T23:41:03.272Z",
      "location_count": 69,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Downey, California + 60 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02452554"
    },
    {
      "nct_id": "NCT06647953",
      "title": "Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pleuropulmonary Blastoma"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Bone Scan",
          "type": "PROCEDURE"
        },
        {
          "name": "Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "Dactinomycin",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Dexrazoxane",
          "type": "DRUG"
        },
        {
          "name": "Doxorubicin",
          "type": "DRUG"
        },
        {
          "name": "Echocardiography Test",
          "type": "PROCEDURE"
        },
        {
          "name": "Ifosfamide",
          "type": "DRUG"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "Multigated Acquisition Scan",
          "type": "PROCEDURE"
        },
        {
          "name": "Patient Observation",
          "type": "OTHER"
        },
        {
          "name": "Positron Emission Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Topotecan",
          "type": "DRUG"
        },
        {
          "name": "Ultrasound Imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "Vincristine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Children's Oncology Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 110,
      "start_date": "2025-03-21",
      "completion_date": "2029-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-05-21T23:41:03.272Z",
      "location_count": 76,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 67 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06647953"
    },
    {
      "nct_id": "NCT03382158",
      "title": "International PPB/DICER1 Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pleuropulmonary Blastoma",
        "Sertoli-Leydig Cell Tumor",
        "DICER1 Syndrome",
        "Cystic Nephroma",
        "Wilms Tumor",
        "Pineoblastoma",
        "Renal Sarcoma",
        "Nodular Hyperplasia of Thyroid",
        "Nasal Chondromesenchymal Hamartoma",
        "Ciliary Body Medulloepithelioma",
        "Neuroblastoma",
        "Pituitary Cancer",
        "Embryonal Rhabdomyosarcoma",
        "Ovarian Sarcoma",
        "Gynandroblastoma",
        "Thyroid Carcinoma",
        "Embryonal Rhabdomyosarcoma of Vagina (Diagnosis)",
        "Embryonal Rhabdomyosarcoma of Uterus (Diagnosis)",
        "Embryonal Rhabdomyosarcoma of Cervix"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospitals and Clinics of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Minutes",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "0 Minutes to 100 Years"
      },
      "enrollment_count": 3400,
      "start_date": "2016-12-06",
      "completion_date": "2035-12-06",
      "has_results": false,
      "last_update_posted_date": "2025-01-30",
      "last_synced_at": "2026-05-21T23:41:03.272Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03382158"
    },
    {
      "nct_id": "NCT00565903",
      "title": "Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pleuropulmonary Blastoma",
        "Cystic Nephroma",
        "Sertoli-Leydig Cell Tumor of Ovary",
        "Medulloepithelioma",
        "Embryonal Rhabdomyosarcoma of Cervix",
        "Goiter",
        "Sarcoma",
        "Pineoblastoma",
        "Pituitary Tumors",
        "Wilms Tumor"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ashley Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "1 Day to 95 Years"
      },
      "enrollment_count": 1247,
      "start_date": "2005-03",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-03-01",
      "last_synced_at": "2026-05-21T23:41:03.272Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00565903"
    },
    {
      "nct_id": "NCT07005297",
      "title": "Clinical Genetics Branch Eligibility Screening Survey",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Melanoma",
        "Li-Fraumeni Syndrome",
        "Pulmonary Blastoma",
        "Chordoma",
        "Congenital Bone Marrow Failure Syndromes",
        "Costello Syndrome",
        "Fanconi Anemia",
        "CFC Syndrome (CFCS)",
        "Legius Syndrome",
        "RASopathies"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "1 Year to 99 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2026-05-25",
      "completion_date": "2036-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-05-21T23:41:03.272Z",
      "location_count": 1,
      "location_summary": "Rockville, Maryland",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07005297"
    },
    {
      "nct_id": "NCT01464606",
      "title": "International Pleuropulmonary Blastoma (PPB) Treatment and Biology Registry",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pleuropulmonary Blastoma"
      ],
      "interventions": [
        {
          "name": "Vincristine",
          "type": "DRUG"
        },
        {
          "name": "Dactinomycin",
          "type": "DRUG"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "Ifosfamide",
          "type": "DRUG"
        },
        {
          "name": "Doxorubicin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospitals and Clinics of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 156,
      "start_date": "2009-12-22",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2024-08-21",
      "last_synced_at": "2026-05-21T23:41:03.272Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01464606"
    }
  ]
}