{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Port-wine+Birthmarks",
    "query": {
      "condition": "Port-wine Birthmarks"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Port-wine+Birthmarks&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:07:42.703Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00800722",
      "title": "A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Port Wine Stain"
      ],
      "interventions": [
        {
          "name": "Rapamycin Treatment of Port Wine Stain",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2008-11",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00800722"
    },
    {
      "nct_id": "NCT01775722",
      "title": "Combined Bipolar Radiofrequency&Pulsed Dye Laser Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Port-Wine Stain"
      ],
      "interventions": [
        {
          "name": "Pulsed Dye Laser",
          "type": "DEVICE"
        },
        {
          "name": "Combined Bipolar Radiofrequency&Pulsed Dye Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2012-12",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2022-11-02",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01775722"
    },
    {
      "nct_id": "NCT00830466",
      "title": "A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Port Wine Stain"
      ],
      "interventions": [
        {
          "name": "Laser and rapamycin versus laser alone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2008-12",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00830466"
    },
    {
      "nct_id": "NCT07183644",
      "title": "Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Port Wine Stains"
      ],
      "interventions": [
        {
          "name": "Pulse Dye laser",
          "type": "DEVICE"
        },
        {
          "name": "Pulse Dye Laser (PDL) pulse width stacking",
          "type": "DEVICE"
        },
        {
          "name": "Pulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser.",
          "type": "DEVICE"
        },
        {
          "name": "IPL (Intense Pulsed Light) followed by Pulse Dye Laser (PDL)",
          "type": "DEVICE"
        },
        {
          "name": "Cupping followed by Pulse Dye Laser (PDL)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Months to 18 Years"
      },
      "enrollment_count": 200,
      "start_date": "2025-09",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-19",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas • Plano, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07183644"
    },
    {
      "nct_id": "NCT00585338",
      "title": "Treatment of Vascular Lesions With a Tandem 532/1064 nm Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Vascular Lesion"
      ],
      "interventions": [
        {
          "name": "Tandem 532/1064 nm Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2007-12",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2022-10-20",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00585338"
    },
    {
      "nct_id": "NCT01774552",
      "title": "Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Port-wine Stain"
      ],
      "interventions": [
        {
          "name": "Photo Acoustic Microscopy and Optical Coherence tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4,
      "start_date": "2012-12",
      "completion_date": "2017-11-28",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01774552"
    },
    {
      "nct_id": "NCT00540371",
      "title": "Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Port Wine Stain"
      ],
      "interventions": [
        {
          "name": "Port wine stain Birthmark",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "1 Month to 75 Years"
      },
      "enrollment_count": 136,
      "start_date": "1999-12",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2022-10-20",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00540371"
    },
    {
      "nct_id": "NCT05171894",
      "title": "A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Port-wine Birthmarks",
        "Port-Wine Stain",
        "Nevus Flammeus"
      ],
      "interventions": [
        {
          "name": "Hemopfin+Green Light",
          "type": "DRUG"
        },
        {
          "name": "Vehicle+Green Light",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 84,
      "start_date": "2024-09-21",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-03-03",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 5,
      "location_summary": "Irvine, California • San Diego, California • Miami, Florida + 2 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Hunt Valley",
          "state": "Maryland"
        },
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05171894"
    },
    {
      "nct_id": "NCT01924273",
      "title": "Novel Treatment for Port Wine Stain Birthmarks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Port-Wine Stain"
      ],
      "interventions": [
        {
          "name": "Talaporfin sodium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2013-06",
      "completion_date": "2017-07-03",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01924273"
    },
    {
      "nct_id": "NCT00573729",
      "title": "Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks: Comparison of 577 nm Versus 595 nm Wavelengths",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Port Wine Stains"
      ],
      "interventions": [
        {
          "name": "Pulsed Dye Laser 577 nm",
          "type": "OTHER"
        },
        {
          "name": "Pulsed Dye Laser 595 nm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Months and older"
      },
      "enrollment_count": 56,
      "start_date": "2007-03",
      "completion_date": "2009-01",
      "has_results": false,
      "last_update_posted_date": "2022-10-20",
      "last_synced_at": "2026-05-22T05:07:42.703Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00573729"
    }
  ]
}