{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post+Operative+Ileus&page=2",
    "query": {
      "condition": "Post Operative Ileus",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post+Operative+Ileus&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:44:20.893Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01662115",
      "title": "Nicotine Gum Recovery After Colorectal Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-operative Ileus"
      ],
      "interventions": [
        {
          "name": "Nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Regular chewing gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 4,
      "start_date": "2012-08",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2017-08-22",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Weston, Florida",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01662115"
    },
    {
      "nct_id": "NCT00387309",
      "title": "Study Evaluating IV Methylnaltrexone for the Treatment of Post Operative Ileus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post Operative Bowel Dysfunction"
      ],
      "interventions": [
        {
          "name": "Methylnaltrexone (MOA-728)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bausch Health Americas, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 495,
      "start_date": "2006-12",
      "completion_date": "2007-11",
      "has_results": false,
      "last_update_posted_date": "2019-11-25",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 59,
      "location_summary": "Mobile, Alabama • Fort Smith, Arkansas • Chula Vista, California + 51 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Fort Smith",
          "state": "Arkansas"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Colton",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00387309"
    },
    {
      "nct_id": "NCT00528970",
      "title": "A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ileus"
      ],
      "interventions": [
        {
          "name": "MOA-728",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bausch Health Americas, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 374,
      "start_date": "2007-10-17",
      "completion_date": "2008-02-05",
      "has_results": true,
      "last_update_posted_date": "2019-09-04",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 75,
      "location_summary": "Benton, Arkansas • Colton, California • Laguna Hills, California + 62 more",
      "locations": [
        {
          "city": "Benton",
          "state": "Arkansas"
        },
        {
          "city": "Colton",
          "state": "California"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00528970"
    },
    {
      "nct_id": "NCT00600158",
      "title": "Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Postoperative Ileus"
      ],
      "interventions": [
        {
          "name": "bupivacaine with hydromorphone",
          "type": "DRUG"
        },
        {
          "name": "lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 45,
      "start_date": "2005-04",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2008-01-24",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00600158"
    },
    {
      "nct_id": "NCT01367548",
      "title": "Intravenous (IV) Methylnaltrexone (MNTX) in the Prevention of Post-Operative Ileus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Ileus"
      ],
      "interventions": [
        {
          "name": "IV Methylnaltrexone (MNTX)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bausch Health Americas, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2003-07",
      "completion_date": "2004-12",
      "has_results": false,
      "last_update_posted_date": "2019-11-27",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Tarrytown, New York",
      "locations": [
        {
          "city": "Tarrytown",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01367548"
    },
    {
      "nct_id": "NCT01911793",
      "title": "Stoma Tube Decompression and Postoperative Ileus After Major Colorectal Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ileus",
        "Bowel Obstruction"
      ],
      "interventions": [
        {
          "name": "Stoma Tube",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2013-07",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2018-03-07",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01911793"
    },
    {
      "nct_id": "NCT00879294",
      "title": "The Effect of Gum Chewing on Postoperative Ileus",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "Motion sickness wristband",
          "type": "DEVICE"
        },
        {
          "name": "Chewing Gum",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-11-06",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00879294"
    },
    {
      "nct_id": "NCT00388401",
      "title": "Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ileus"
      ],
      "interventions": [
        {
          "name": "Alvimopan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 510,
      "start_date": "2002-01",
      "completion_date": "2003-06",
      "has_results": false,
      "last_update_posted_date": "2015-07-20",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Exton, Pennsylvania",
      "locations": [
        {
          "city": "Exton",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00388401"
    },
    {
      "nct_id": "NCT05334485",
      "title": "Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Postoperative Ileus"
      ],
      "interventions": [
        {
          "name": "Pyridostigmine Bromide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Stefan Holubar MD MS FACS, FASCRS",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-09-03",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05334485"
    },
    {
      "nct_id": "NCT05796063",
      "title": "Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ileus Postoperative",
        "Postoperative Nausea and Vomiting"
      ],
      "interventions": [
        {
          "name": "gastric point of care ultrasound",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 128,
      "start_date": "2023-04-01",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-04-07",
      "last_synced_at": "2026-05-22T05:44:20.893Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05796063"
    }
  ]
}