{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-Operative+Complications+in+Cardiac+Surgery",
    "query": {
      "condition": "Post-Operative Complications in Cardiac Surgery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 63,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-Operative+Complications+in+Cardiac+Surgery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T14:13:36.859Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00260494",
      "title": "Acupuncture and Post-Surgical Wound Healing",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Complications",
        "Surgical Wound Infection",
        "Surgical Wound Dehiscence"
      ],
      "interventions": [
        {
          "name": "acupuncture",
          "type": "OTHER"
        },
        {
          "name": "sham acupuncture",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2005-03",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2013-07-23",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00260494"
    },
    {
      "nct_id": "NCT03810417",
      "title": "Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "Digoxin Antibodies Fab Fragments",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Baseline EO > 360 pM",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "EO < 360 pM",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 267,
      "start_date": "2019-07-22",
      "completion_date": "2024-04-30",
      "has_results": true,
      "last_update_posted_date": "2025-07-02",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03810417"
    },
    {
      "nct_id": "NCT03558984",
      "title": "D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgical Site Infection",
        "Sternal Infection",
        "Cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "D-PLEX",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "PolyPid Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2019-12-17",
      "completion_date": "2022-10-24",
      "has_results": false,
      "last_update_posted_date": "2022-11-15",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • Houston, Texas",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03558984"
    },
    {
      "nct_id": "NCT05279898",
      "title": "Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Delirium",
        "Hemodynamic Instability",
        "Pain",
        "Neurocognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "EEG Monitoring",
          "type": "DEVICE"
        },
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Remifentanil",
          "type": "DRUG"
        },
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Rocuronium",
          "type": "DRUG"
        },
        {
          "name": "Propofol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2023-02-28",
      "completion_date": "2024-12-31",
      "has_results": true,
      "last_update_posted_date": "2025-11-26",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05279898"
    },
    {
      "nct_id": "NCT00164099",
      "title": "The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Surgical Wound Infection",
        "Cystitis",
        "Bacteremia",
        "Pneumonia",
        "Enterocolitis, Pseudomembranous"
      ],
      "interventions": [
        {
          "name": "Synbiotic 2000",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beth Israel Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 40,
      "start_date": "2005-11",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2007-11-01",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00164099"
    },
    {
      "nct_id": "NCT06434948",
      "title": "The Effect of Omega 3 Supplementation on Postoperative Delirium in Elderly Patients Undergoing Major Cardiac Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Delirium"
      ],
      "interventions": [
        {
          "name": "Omega-3 Ethyl Esters 4 g",
          "type": "DRUG"
        },
        {
          "name": "Omega-3 Ethyl Esters 2 g",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2026-03-03",
      "completion_date": "2026-04-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06434948"
    },
    {
      "nct_id": "NCT02783157",
      "title": "Transcutaneous Autonomic Modulation in Thoracic Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation, Postoperative",
        "Postoperative Complications",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham LLVNS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 2,
      "start_date": "2016-05",
      "completion_date": "2020-02-21",
      "has_results": false,
      "last_update_posted_date": "2020-04-06",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02783157"
    },
    {
      "nct_id": "NCT01561378",
      "title": "Cardiac Surgery Neuroprotection Study in Elders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post-operative Cognitive Decline",
        "Post-operative Delirium"
      ],
      "interventions": [
        {
          "name": "Aspart insulin",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        },
        {
          "name": "Intranasal mucosal atomizer device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2012-08",
      "completion_date": "2014-10",
      "has_results": true,
      "last_update_posted_date": "2021-11-10",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01561378"
    },
    {
      "nct_id": "NCT06021457",
      "title": "Effect of RBT-1 on Reducing the Risk of Post-Operative Complications in Subjects Undergoing Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post-Operative Complications in Cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "RBT-1",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Renibus Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 454,
      "start_date": "2023-10-17",
      "completion_date": "2025-06-17",
      "has_results": false,
      "last_update_posted_date": "2025-08-01",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 31,
      "location_summary": "Huntsville, Alabama • La Jolla, California • San Francisco, California + 27 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06021457"
    },
    {
      "nct_id": "NCT04976530",
      "title": "Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemorrhage, Surgical",
        "Blood Loss, Surgical",
        "Blood Loss, Postoperative",
        "Hemorrhage Postoperative"
      ],
      "interventions": [
        {
          "name": "DrugSorb-ATR system",
          "type": "DEVICE"
        },
        {
          "name": "Sham comparator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CytoSorbents, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2021-08-31",
      "completion_date": "2023-08-07",
      "has_results": true,
      "last_update_posted_date": "2025-04-11",
      "last_synced_at": "2026-06-26T14:13:36.859Z",
      "location_count": 22,
      "location_summary": "Sacramento, California • New Haven, Connecticut • Washington D.C., District of Columbia + 18 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04976530"
    }
  ]
}