{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-Operative+Inflammation",
    "query": {
      "condition": "Post-Operative Inflammation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 86,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-Operative+Inflammation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T14:26:29.304Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05378659",
      "title": "Neuroinflammation and Alzheimer's Pathology in POCD",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-Operative Confusion",
        "Neuroinflammatory Response",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Montreal Cognitive Assessment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stroop Test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "4AT Delirium",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Grooved Pegboard",
          "type": "BEHAVIORAL"
        },
        {
          "name": "NACC Cognitive Battery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "ERP Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Plasma and Serum sampling",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Cerebral Spinal Fluid Sample",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Tennessee Graduate School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2021-11-01",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-05-18",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05378659"
    },
    {
      "nct_id": "NCT03727776",
      "title": "Adrenocorticotropic Hormone (ACTH) for Post-op Inflammation in Proliferative Vitreoretinopathy (PVR)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Proliferative Vitreoretinopathy"
      ],
      "interventions": [
        {
          "name": "Adrenocorticotropic Hormone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2019-08-19",
      "completion_date": "2023-07-07",
      "has_results": false,
      "last_update_posted_date": "2023-08-08",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03727776"
    },
    {
      "nct_id": "NCT00358423",
      "title": "The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cystoid Macular Edema"
      ],
      "interventions": [
        {
          "name": "Pegaptanib Sodium",
          "type": "DRUG"
        },
        {
          "name": "Control",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2006-07",
      "completion_date": "2007-02",
      "has_results": false,
      "last_update_posted_date": "2008-05-12",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00358423"
    },
    {
      "nct_id": "NCT06896240",
      "title": "Fiber Smoothie Supplement",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty Revision",
        "Inflammatory Markers",
        "Gut Microbiota"
      ],
      "interventions": [
        {
          "name": "Assigned Interventions",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 24,
      "start_date": "2026-04-28",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06896240"
    },
    {
      "nct_id": "NCT04079829",
      "title": "Postoperative Respiratory Abnormalities",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Failure",
        "Respiratory Arrest",
        "Respiratory Distress Syndrome",
        "Acute Respiratory Failure",
        "Acute Respiratory Failure With Hypoxia",
        "Acute Respiratory Failure With Hypercapnia",
        "Acute Respiratory Failure Post Surgical",
        "Acute Respiratory Failure Postprocedural",
        "Acute Respiratory Failure Following Trauma and Surgery",
        "Acute Respiratory Failure Requiring Reintubation",
        "Acute Respiratory Failure Post Traumatic",
        "Acute Respiratory Decompensation",
        "Shock",
        "Shock, Septic",
        "Shock, Cardiogenic",
        "Acute Cardiac Failure",
        "Multi Organ Failure",
        "Acute Kidney Failure"
      ],
      "interventions": [
        {
          "name": "Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Efficacy Care R&D Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 50000,
      "start_date": "2019-09-01",
      "completion_date": "2020-10",
      "has_results": false,
      "last_update_posted_date": "2020-06-24",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04079829"
    },
    {
      "nct_id": "NCT06480708",
      "title": "Evaluation of the Ketogenic Diet to Improve Post Operative Cognitive Decline in Cardiac Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Ketogenic diet",
          "type": "OTHER"
        },
        {
          "name": "Control diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2026-01-15",
      "completion_date": "2026-05-28",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06480708"
    },
    {
      "nct_id": "NCT02355691",
      "title": "Improvement in Wound Healing With Negative Pressure Wound Therapy for Postoperative Total Hip Arthroplasty",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Complications; Arthroplasty, Infection or Inflammation",
        "Wound Complication"
      ],
      "interventions": [
        {
          "name": "PREVENA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2015-05",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2018-04-17",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02355691"
    },
    {
      "nct_id": "NCT03802396",
      "title": "Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Delirium",
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "CN-105",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Miles Berger, MD PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 203,
      "start_date": "2018-07-15",
      "completion_date": "2022-12-28",
      "has_results": true,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03802396"
    },
    {
      "nct_id": "NCT07588074",
      "title": "Tolerability Comparison of Flarex to Lotemax SM",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Ocular Inflammation",
        "Keratoconjunctivitis",
        "Dry Eye Disease (DED)",
        "Post-operative Complications",
        "Kerato Conjunctivitis Sicca",
        "Dry Eye Syndromes",
        "Postoperative Complications"
      ],
      "interventions": [
        {
          "name": "Fluorometholone Acetate Ophthalmic Suspension 0.1%",
          "type": "DRUG"
        },
        {
          "name": "Loteprednol Etabonate Ophthalmic Gel 0.38%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Harrow Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2021-05-01",
      "completion_date": "2021-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07588074"
    },
    {
      "nct_id": "NCT01576003",
      "title": "Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bloodstream Infections",
        "Short Bowel Syndrome",
        "Development",
        "Nutrition",
        "Biological Markers"
      ],
      "interventions": [
        {
          "name": "Glutamine",
          "type": "DRUG"
        },
        {
          "name": "L-alanine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Weeks",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "6 Weeks to 12 Months"
      },
      "enrollment_count": 10,
      "start_date": "2012-04",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2020-06-11",
      "last_synced_at": "2026-07-22T14:26:29.304Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01576003"
    }
  ]
}