{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-operative+Cognitive+Dysfunction&page=2",
    "query": {
      "condition": "Post-operative Cognitive Dysfunction",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-operative+Cognitive+Dysfunction&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:23:40.096Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07217912",
      "title": "Daridorexant to Prevent Post-cardiotomy Delirium",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Cognitive Decline",
        "Postoperative Delirium"
      ],
      "interventions": [
        {
          "name": "Daridorexant 50 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2025-10-14",
      "completion_date": "2027-11-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07217912"
    },
    {
      "nct_id": "NCT02908464",
      "title": "Prevention of Early Postoperative Decline",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium",
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Lumosity",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "60 Years to 90 Years"
      },
      "enrollment_count": 45,
      "start_date": "2016-11",
      "completion_date": "2019-09",
      "has_results": true,
      "last_update_posted_date": "2020-06-16",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02908464"
    },
    {
      "nct_id": "NCT02598050",
      "title": "Preoperative Cognitive Screening in Older Surgical Patients Utility for Predicting Morbidity",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "No Interventions as this is a observational study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2016-02-01",
      "completion_date": "2017-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-04-15",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02598050"
    },
    {
      "nct_id": "NCT01199913",
      "title": "POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "1. Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "The intervention will be Mini-Mental Status Examination (MMSE)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2010-08",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2014-09-09",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01199913"
    },
    {
      "nct_id": "NCT06052397",
      "title": "Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Delirium, Postoperative",
        "Cognitive Decline",
        "Dementia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "70 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2023-09-12",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-11",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06052397"
    },
    {
      "nct_id": "NCT04189861",
      "title": "Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "60 Years to 80 Years"
      },
      "enrollment_count": 31,
      "start_date": "2020-01-24",
      "completion_date": "2025-11-11",
      "has_results": false,
      "last_update_posted_date": "2026-01-14",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04189861"
    },
    {
      "nct_id": "NCT02230605",
      "title": "Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium"
      ],
      "interventions": [
        {
          "name": "Mini-Mental State Examination",
          "type": "OTHER"
        },
        {
          "name": "Self-Administered Gerocognitive Examination",
          "type": "OTHER"
        },
        {
          "name": "Geriatric Depression Scale",
          "type": "OTHER"
        },
        {
          "name": "Charlson Comorbidity Index",
          "type": "OTHER"
        },
        {
          "name": "Short Form 36 Health Survey",
          "type": "OTHER"
        },
        {
          "name": "Confusion Assessment Method",
          "type": "OTHER"
        },
        {
          "name": "Memorial Delirium Assessment Scale",
          "type": "OTHER"
        },
        {
          "name": "Postoperative Quality of Recovery Scale",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 322,
      "start_date": "2015-07",
      "completion_date": "2019-08-20",
      "has_results": false,
      "last_update_posted_date": "2019-09-11",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02230605"
    },
    {
      "nct_id": "NCT06133842",
      "title": "CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Perioperative/Postoperative Complications",
        "Postoperative Cognitive Dysfunction",
        "Postoperative Delirium",
        "EEG With Periodic Abnormalities",
        "Intraoperative Hypotension",
        "Cerebral Hypoperfusion"
      ],
      "interventions": [
        {
          "name": "Intra-op EEG and CO data collection",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2024-04-17",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2025-10-28",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06133842"
    },
    {
      "nct_id": "NCT04566562",
      "title": "Blood Brain Barrier Dysfunction and Postoperative Neurocognitive Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neurocognitive Disorders",
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Brain Imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Cognitive Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Biomarkers",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "65 Years to 75 Years"
      },
      "enrollment_count": 32,
      "start_date": "2020-08-03",
      "completion_date": "2024-02-29",
      "has_results": false,
      "last_update_posted_date": "2024-12-10",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04566562"
    },
    {
      "nct_id": "NCT07577726",
      "title": "Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Postoperative Cognitive Complications",
        "Delirium",
        "Perioperative/Postoperative Complications",
        "Brain Injuries",
        "Anesthesia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2026-07",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-06-11T04:23:40.096Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07577726"
    }
  ]
}