{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-operative+Tooth+Pain",
    "query": {
      "condition": "Post-operative Tooth Pain"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 49,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Post-operative+Tooth+Pain&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T06:05:37.070Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06864884",
      "title": "A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Acute Post Operative Pain",
        "Third Molar Extraction Surgery"
      ],
      "interventions": [
        {
          "name": "ARC-001",
          "type": "DRUG"
        },
        {
          "name": "Placebo gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Arcato Laboratories, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-02-26",
      "completion_date": "2026-02",
      "has_results": false,
      "last_update_posted_date": "2025-03-11",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06864884"
    },
    {
      "nct_id": "NCT03224403",
      "title": "Randomized, Double-Blind, Single-Dose, Efficacy and Safety Study of Test Acetaminophen Tablet in Postoperative Dental Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post-operative Dental Pain"
      ],
      "interventions": [
        {
          "name": "Test acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Commercial acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Commercial ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "17 Years to 50 Years"
      },
      "enrollment_count": 664,
      "start_date": "2017-07-19",
      "completion_date": "2018-04-12",
      "has_results": true,
      "last_update_posted_date": "2021-04-15",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03224403"
    },
    {
      "nct_id": "NCT02476422",
      "title": "A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post Operative Dental Pain"
      ],
      "interventions": [
        {
          "name": "Diclofenac potassium",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Placebo to ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Placebo to diclofenac potassium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 328,
      "start_date": "2015-04",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2016-10-17",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02476422"
    },
    {
      "nct_id": "NCT01929031",
      "title": "Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Tooth Diseases"
      ],
      "interventions": [
        {
          "name": "ibuprofen + caffeine",
          "type": "DRUG"
        },
        {
          "name": "ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "caffeine",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boehringer Ingelheim",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 562,
      "start_date": "2013-08",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2016-11-16",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01929031"
    },
    {
      "nct_id": "NCT01490931",
      "title": "Intranasal Ketorolac for Postsurgical Pain in Dental Implant Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acute Pain"
      ],
      "interventions": [
        {
          "name": "Ketorolac Nasal Spray",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hersh, Elliot V., DMD, MS, PhD",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 28,
      "start_date": "2011-11",
      "completion_date": "2012-08",
      "has_results": true,
      "last_update_posted_date": "2014-05-09",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01490931"
    },
    {
      "nct_id": "NCT05317312",
      "title": "Study of MR-107A-02 in the Treatment of Post Surgical Dental Pain.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Pain",
        "Post Operative Pain",
        "Pain"
      ],
      "interventions": [
        {
          "name": "MR-107A-02",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mylan Specialty, LP",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 111,
      "start_date": "2022-03-31",
      "completion_date": "2022-06-20",
      "has_results": true,
      "last_update_posted_date": "2023-08-07",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05317312"
    },
    {
      "nct_id": "NCT01201681",
      "title": "DPBRN Peri-operative Pain and Root Canal Therapy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-operative Tooth Pain",
        "Root Canal Therapy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dental Practice-Based Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "19 Years to 70 Years"
      },
      "enrollment_count": 500,
      "start_date": "2010-07",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2011-09-20",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 7,
      "location_summary": "Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01201681"
    },
    {
      "nct_id": "NCT02209181",
      "title": "A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "JNJ-10450232 / Not yet marketed",
          "type": "DRUG"
        },
        {
          "name": "acetaminophen / Tylenol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 269,
      "start_date": "2014-08",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2017-02-03",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02209181"
    },
    {
      "nct_id": "NCT01982799",
      "title": "Local Anesthesia and Analgesics in Endodontic Pain",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Odontalgia"
      ],
      "interventions": [
        {
          "name": "Oral placebo",
          "type": "DRUG"
        },
        {
          "name": "Oral ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "oral naproxen",
          "type": "DRUG"
        },
        {
          "name": "oral acetaminophen/hydrocodone + ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2014-02",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2016-11-03",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01982799"
    },
    {
      "nct_id": "NCT04447040",
      "title": "Acetaminophen/Naproxen Sodium Dose Ranging Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Acetaminophen/naproxen sodium Dose A",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen/naproxen sodium Dose B",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen/naproxen sodium Dose C",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen/naproxen sodium Dose D",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen/naproxen sodium Dose E",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "17 Years to 50 Years"
      },
      "enrollment_count": 304,
      "start_date": "2020-11-09",
      "completion_date": "2021-05-03",
      "has_results": true,
      "last_update_posted_date": "2025-03-24",
      "last_synced_at": "2026-07-24T06:05:37.070Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04447040"
    }
  ]
}