{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postinflammatory+Hyperpigmentation",
    "query": {
      "condition": "Postinflammatory Hyperpigmentation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postinflammatory+Hyperpigmentation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T08:46:44.711Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01038869",
      "title": "Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acne Vulgaris",
        "Post Inflammatory Hyperpigmentation"
      ],
      "interventions": [
        {
          "name": "Azelaic acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Derm Research, PLLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-12",
      "completion_date": "2010-05",
      "has_results": true,
      "last_update_posted_date": "2012-09-25",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01038869"
    },
    {
      "nct_id": "NCT06938815",
      "title": "A Novel Regimen for Treatment and Prevention of Post-Inflammatory Hyperpigmentation in Skin of Color",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post Inflammatory Hyperpigmentation"
      ],
      "interventions": [
        {
          "name": "Pigment Balancing Peel",
          "type": "OTHER"
        },
        {
          "name": "Discoloration Defense Serum",
          "type": "OTHER"
        },
        {
          "name": "LHA Cleansing Gel",
          "type": "OTHER"
        },
        {
          "name": "Hydrating B5 Gel",
          "type": "OTHER"
        },
        {
          "name": "Daily Brightening Sunscreen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Narrows Institute for Biomedical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2025-02-28",
      "completion_date": "2025-07-20",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06938815"
    },
    {
      "nct_id": "NCT03402893",
      "title": "The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acne Vulgaris",
        "Post Inflammatory Hyperpigmentation"
      ],
      "interventions": [
        {
          "name": "ONEXTON Topical Gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Derm Research, PLLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2017-07-28",
      "completion_date": "2018-02-28",
      "has_results": true,
      "last_update_posted_date": "2019-04-02",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03402893"
    },
    {
      "nct_id": "NCT01111994",
      "title": "Efficacy & Safety of Clindamycin and Tretinoin in Acne",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acne"
      ],
      "interventions": [
        {
          "name": "Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Callender Center for Clinical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2009-11",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2010-05-20",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 2,
      "location_summary": "Mitchellville, Maryland • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Mitchellville",
          "state": "Maryland"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01111994"
    },
    {
      "nct_id": "NCT05327361",
      "title": "LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acne",
        "Post Inflammatory Hyperpigmentation"
      ],
      "interventions": [
        {
          "name": "Liftactiv B3",
          "type": "DRUG"
        },
        {
          "name": "Sunscreen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 13,
      "start_date": "2022-03-22",
      "completion_date": "2023-03-06",
      "has_results": true,
      "last_update_posted_date": "2024-04-03",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05327361"
    },
    {
      "nct_id": "NCT06149780",
      "title": "Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Patients treated with laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2023-11-15",
      "completion_date": "2026-08-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06149780"
    },
    {
      "nct_id": "NCT02905903",
      "title": "An In Vivo Model for Postinflammatory Hyperpigmentation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-inflammatory Hyperpigmentation"
      ],
      "interventions": [
        {
          "name": "Tricholoacetic Acid (TCA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 30,
      "start_date": "2016-02-14",
      "completion_date": "2019-06-21",
      "has_results": false,
      "last_update_posted_date": "2022-03-02",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02905903"
    },
    {
      "nct_id": "NCT07501000",
      "title": "Evaluation of the Safety and Tolerability of a Brightening Treatment Paired With a Skincare Regimen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperpigmentation",
        "Skin Ageing",
        "Post Inflammatory Hyperpigmentation",
        "Skin Roughness"
      ],
      "interventions": [
        {
          "name": "Brightening Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 65 Years · Female only"
      },
      "enrollment_count": 11,
      "start_date": "2024-10-07",
      "completion_date": "2025-01-23",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07501000"
    },
    {
      "nct_id": "NCT05704114",
      "title": "Tazarotene 0.045% Lotion for Treating PIE and PIH in Subjects With Acne",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acne Vulgaris",
        "Post Inflammatory Hyperpigmentation",
        "Post Inflammatory Pigmentation Change",
        "Erythema",
        "Skin Scarring"
      ],
      "interventions": [
        {
          "name": "Tazarotene 0.045% Lotion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dr. Emmy Graber",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-02-01",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2023-01-30",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05704114"
    },
    {
      "nct_id": "NCT03361345",
      "title": "Topical 5% Tranexamic Acid as a Treatment for Postinflammatory Hyperpigmentation Due to Acne Vulgaris",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Postinflammatory Hyperpigmentation"
      ],
      "interventions": [
        {
          "name": "Tranexamic Acid",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-11-01",
      "completion_date": "2022-01-09",
      "has_results": false,
      "last_update_posted_date": "2023-05-16",
      "last_synced_at": "2026-06-10T08:46:44.711Z",
      "location_count": 1,
      "location_summary": "Dearborn, Michigan",
      "locations": [
        {
          "city": "Dearborn",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03361345"
    }
  ]
}