{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postoperative+Depression&page=2", "query": { "condition": "Postoperative Depression", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postoperative+Depression&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T09:45:52.337Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07221786", "title": "Preoperative Opioid Tapering Before Spine Surgery", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Opioid Consumption, Postoperative", "Pain After Surgery", "Opioid Dependency" ], "interventions": [ { "name": "Opioid tapering with CBT and education", "type": "OTHER" }, { "name": "Opioid tapering with education alone", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Thomas Jefferson University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 45, "start_date": "2025-12-01", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-03-24", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "Philadephia, Pennsylvania", "locations": [ { "city": "Philadephia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07221786" }, { "nct_id": "NCT05658796", "title": "RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mood Disorders", "Anxiety", "Depressive Symptoms", "Depression", "Anxiety Disorders", "Anxiety Depression" ], "interventions": [ { "name": "-RxWell", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 150, "start_date": "2023-01-27", "completion_date": "2026-12-30", "has_results": false, "last_update_posted_date": "2025-11-05", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 3, "location_summary": "Monroeville, Pennsylvania • Pittsburgh, Pennsylvania", "locations": [ { "city": "Monroeville", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05658796" }, { "nct_id": "NCT04046068", "title": "Multimodal Perioperative Pain Management: ComfortSafe Program", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Post-operative Pain", "Post-operative Nausea and Vomiting", "Respiratory Depression", "Confusion Postoperative" ], "interventions": [ { "name": "ComfortSafe Care", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Georgetown University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "21 Years to 75 Years" }, "enrollment_count": 60, "start_date": "2020-05-11", "completion_date": "2021-09", "has_results": false, "last_update_posted_date": "2020-10-05", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04046068" }, { "nct_id": "NCT05233566", "title": "Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Depression" ], "interventions": [ { "name": "Ketamine", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2022-04-25", "completion_date": "2023-03-08", "has_results": true, "last_update_posted_date": "2026-02-12", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05233566" }, { "nct_id": "NCT06583395", "title": "Quest to Analyze One Thousand Humans Meditating", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Amyotrophic Lateral Sclerosis (ALS)", "Angina, Stable", "Anxiety", "Asthma", "Atrial Fibrillation", "Cancer Brain", "Cancer, Breast", "Cancer Colon", "Cancer, Lung", "Cancer, Ovarian", "Cancer Prostate", "Cancer Skin", "Throat Cancer", "Lymphoma", "Cancer, Thyroid", "Cancer, Other", "Cerebral Palsy", "Chronic Fatigue Syndrome", "Cluster Headache", "Chronic Obstructive Pulmonary Disease (COPD)", "Chronic Kidney Diseases", "Crohn Disease", "Deafness", "Depression", "Diabetes", "Eczema", "Epilepsy", "Fibroids", "Fibromyalgia", "Heart Failure", "Hypertension", "Hyperthyroidism", "Hypothyroidism", "Irritable Bowel Syndrome (IBS)", "Infertility", "Lyme Disease", "Macular Degeneration", "Migraine", "Multiple Allergies", "Multiple Sclerosis", "Osteoarthritis", "Osteoporosis", "Ovarian Cysts", "Parkinson Disease", "Phantom Limb Pain", "Psoriasis", "Post Traumatic Stress Disorder (PTSD)", "Rheumatoid Arthritis", "Sjogrens Disease", "Spinal Cord Injury", "Spinal Stenosis", "Stroke", "Tension Headache", "Tinnitus", "Ulcerative Colitis" ], "interventions": [ { "name": "Advanced multi-component meditation practice", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Tobias Moeller-Bertram", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 3000, "start_date": "2021-12-05", "completion_date": "2025-03-25", "has_results": false, "last_update_posted_date": "2024-11-01", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "Palm Desert, California", "locations": [ { "city": "Palm Desert", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06583395" }, { "nct_id": "NCT01839461", "title": "Pharmacogenetic Morphine Spine Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pain" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "10 Years to 18 Years" }, "enrollment_count": 137, "start_date": "2009-07", "completion_date": "2019-04-02", "has_results": false, "last_update_posted_date": "2019-10-07", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01839461" }, { "nct_id": "NCT06938542", "title": "Palliative Care Needs of Children With Rare Diseases and Their Families", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Trisomy 13 Syndrome", "Arthrogryposis Congenita Multiplex With Intestinal Atresia", "Asparagine Synthetase Deficiency", "CHARGE Syndrome", "Early Infantile Epileptic Encephalopathy", "FOXG1 Syndrome", "KBG Syndrome", "Noonan Syndrome", "Severe Hemophilia A", "Short Bowel Syndrome", "Beta-Propeller Protein-Associated Neurodegeneration", "Brain Injury of Prematurity With Periventricular Leukomalacia", "Chromosome 17p13.3 Microdeletion Syndrome", "Chromosome 1q43-1q44 Deletion", "Cockayne Syndrome", "Congenital Diaphragmatic Hernia", "End-Stage Renal Disease With Cloacal Anomaly", "Mitochondrial Depletion Disorder", "Severe Factor VII Deficiency" ], "interventions": [ { "name": "Family Centered pediatric palliative care for family caregivers of children with rare diseases.", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Children's National Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Months", "maximum_age": "99 Years", "sex": "ALL", "summary": "12 Months to 99 Years" }, "enrollment_count": 480, "start_date": "2025-10-02", "completion_date": "2029-08-02", "has_results": false, "last_update_posted_date": "2026-01-28", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06938542" }, { "nct_id": "NCT07218289", "title": "Green Light for Post-Operative Wellness", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Surgery" ], "interventions": [ { "name": "Bright Green Light Therapy", "type": "DEVICE" }, { "name": "Dim White Light Therapy", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Rebecca E Kotcher, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2026-01-14", "completion_date": "2026-12-01", "has_results": false, "last_update_posted_date": "2026-02-12", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07218289" }, { "nct_id": "NCT01298778", "title": "High Pain Intervention in Cesarean Sections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Other Chronic Postoperative Pain" ], "interventions": [ { "name": "Duramorph 150", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Duramorph 300", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "18 Years to 45 Years · Female only" }, "enrollment_count": 69, "start_date": "2010-08", "completion_date": "2011-07", "has_results": true, "last_update_posted_date": "2018-09-10", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01298778" }, { "nct_id": "NCT06903819", "title": "Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Orthopedic Trauma Surgery Patients", "Postoperative Pain", "Opioid Use", "Depression", "Post-traumatic Stress Disorder (PTSD)" ], "interventions": [ { "name": "Ketamine", "type": "DRUG" }, { "name": "standard general anesthesia", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Texas Tech University Health Sciences Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 90, "start_date": "2025-11-06", "completion_date": "2028-05", "has_results": false, "last_update_posted_date": "2026-03-24", "last_synced_at": "2026-05-22T09:45:52.337Z", "location_count": 2, "location_summary": "Lubbock, Texas", "locations": [ { "city": "Lubbock", "state": "Texas" }, { "city": "Lubbock", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06903819" } ] }