{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postoperative+Edema&page=2",
    "query": {
      "condition": "Postoperative Edema",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postoperative+Edema&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:12:55.501Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04951128",
      "title": "The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Edema",
        "Ecchymosis; Eyelid"
      ],
      "interventions": [
        {
          "name": "Tranexamic acid injection",
          "type": "DRUG"
        },
        {
          "name": "Local anesthetic control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Consultants in Ophthalmic and Facial Plastics Surgery",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2021-08-01",
      "completion_date": "2022-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-07-06",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 4,
      "location_summary": "Southfield, Michigan • The Bronx, New York • Houston, Texas",
      "locations": [
        {
          "city": "Southfield",
          "state": "Michigan"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04951128"
    },
    {
      "nct_id": "NCT04549935",
      "title": "The PRIME Study: A Randomized, Controlled, Prospective Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Patient Preference",
        "Patient Outcomes",
        "Post-Operative Inflammation",
        "Grade of Post-Operative Cystoid Macular Edema",
        "Rate of Post-Operative Cystoid Macular Edema"
      ],
      "interventions": [
        {
          "name": "Dextenza",
          "type": "DRUG"
        },
        {
          "name": "Topical Prednisolone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vance Thompson Vision - MT",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-09-14",
      "completion_date": "2021-08-27",
      "has_results": false,
      "last_update_posted_date": "2020-09-16",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 1,
      "location_summary": "Bozeman, Montana",
      "locations": [
        {
          "city": "Bozeman",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04549935"
    },
    {
      "nct_id": "NCT06057675",
      "title": "Tranexamic Acid in Nasal Mohs Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Bleeding",
        "Skin Cancer Face"
      ],
      "interventions": [
        {
          "name": "Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine)",
          "type": "DRUG"
        },
        {
          "name": "Control (1% lidocaine with 1:100,000 epinephrine)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2024-03-19",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-08-19",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06057675"
    },
    {
      "nct_id": "NCT05142800",
      "title": "Screening For BCRL In Targeted Therapy For Breast Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphedema",
        "Lymphedema Arm",
        "Lymphedema of Upper Arm",
        "Lymphedema of Upper Limb",
        "Lymphedema of the Hands",
        "Edema",
        "Edema Arm",
        "Breast Cancer Lymphedema",
        "Breast Cancer Metastatic",
        "Breast Cancer Stage",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Perometer",
          "type": "DEVICE"
        },
        {
          "name": "SOZO device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 166,
      "start_date": "2018-12-13",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-05-22",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05142800"
    },
    {
      "nct_id": "NCT01244334",
      "title": "Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cataracts",
        "Corneal Edema",
        "Retinal Structural Change, Deposit and Degeneration",
        "Visual Acuity Reduced Transiently"
      ],
      "interventions": [
        {
          "name": "Difluprednate ophthalmic emulsion 0.05%",
          "type": "DRUG"
        },
        {
          "name": "Prednisolone acetate 1%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Edward J. Holland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2009-03",
      "completion_date": "2010-11",
      "has_results": false,
      "last_update_posted_date": "2012-08-08",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 3,
      "location_summary": "Edgewood, Kentucky • Lynbrook, New York • Mt. Pleasant, South Carolina",
      "locations": [
        {
          "city": "Edgewood",
          "state": "Kentucky"
        },
        {
          "city": "Lynbrook",
          "state": "New York"
        },
        {
          "city": "Mt. Pleasant",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01244334"
    },
    {
      "nct_id": "NCT02105298",
      "title": "Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Failure",
        "Acute Respiratory Failure Requiring Reintubation",
        "Pulmonary Edema",
        "Pneumonia",
        "Hypoxia",
        "Acute Kidney Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104000,
      "start_date": "2013-09",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2015-08-21",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02105298"
    },
    {
      "nct_id": "NCT00118820",
      "title": "Antibiotic Efficacy in Third Molar Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Alveolar Osteitis",
        "Dry Socket",
        "Infection"
      ],
      "interventions": [
        {
          "name": "IV Preoperative antibiotic or placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2004-03",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2010-07-16",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00118820"
    },
    {
      "nct_id": "NCT00494494",
      "title": "Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cystoid Macular Edema"
      ],
      "interventions": [
        {
          "name": "Standard Care",
          "type": "DRUG"
        },
        {
          "name": "nepafenac",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 82,
      "start_date": "2007-06",
      "completion_date": "2008-04",
      "has_results": true,
      "last_update_posted_date": "2011-07-12",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00494494"
    },
    {
      "nct_id": "NCT02376946",
      "title": "Third Molar Extraction and Pulsed Electromagnetic FieldTherapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Edema and Pain"
      ],
      "interventions": [
        {
          "name": "ActiPatch(TM)",
          "type": "DEVICE"
        },
        {
          "name": "Placebo",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 49,
      "start_date": "2014-01",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2021-11-01",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02376946"
    },
    {
      "nct_id": "NCT06261346",
      "title": "Plasma Rich in Growth Factors in Corneal Endothelial Transplantation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fuchs' Endothelial Dystrophy",
        "Corneal Edema"
      ],
      "interventions": [
        {
          "name": "Endothelial keratoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "PRGF",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2024-07-15",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-05-22T08:12:55.501Z",
      "location_count": 2,
      "location_summary": "Miami, Florida • Indianapolis, Indiana",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06261346"
    }
  ]
}