{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postoperative+Neurocognitive+Disorder",
    "query": {
      "condition": "Postoperative Neurocognitive Disorder"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 149,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Postoperative+Neurocognitive+Disorder&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T03:03:28.630Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06567574",
      "title": "Stanford PIPRA Validation Study in an Elderly Orthopedic Population",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Delirium",
        "Postoperative Delirium",
        "Cognitive Impairment"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2024-04-30",
      "completion_date": "2024-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-08-22",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06567574"
    },
    {
      "nct_id": "NCT00535613",
      "title": "Propofol in Emergence Agitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Emergence Agitation"
      ],
      "interventions": [
        {
          "name": "Propofol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "12 Months to 6 Years"
      },
      "enrollment_count": 99,
      "start_date": "2007-08",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2019-10-21",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00535613"
    },
    {
      "nct_id": "NCT03089866",
      "title": "Effect of Sedation on Cognitive Performance in the Elderly",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Midazolam (0.02mg/kg)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2015-03",
      "completion_date": "2020-09-04",
      "has_results": false,
      "last_update_posted_date": "2025-07-11",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03089866"
    },
    {
      "nct_id": "NCT00590707",
      "title": "Post-Operative Delirium in Elderly Surgical Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hip Fractures",
        "Delirium"
      ],
      "interventions": [
        {
          "name": "Deeper sedation",
          "type": "DEVICE"
        },
        {
          "name": "Moderate sedation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2005-01",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2018-06-11",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00590707"
    },
    {
      "nct_id": "NCT01561378",
      "title": "Cardiac Surgery Neuroprotection Study in Elders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post-operative Cognitive Decline",
        "Post-operative Delirium"
      ],
      "interventions": [
        {
          "name": "Aspart insulin",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        },
        {
          "name": "Intranasal mucosal atomizer device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2012-08",
      "completion_date": "2014-10",
      "has_results": true,
      "last_update_posted_date": "2021-11-10",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01561378"
    },
    {
      "nct_id": "NCT00990769",
      "title": "The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emergence Agitation"
      ],
      "interventions": [
        {
          "name": "Depth of anesthesia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "2 Years to 8 Years"
      },
      "enrollment_count": 40,
      "start_date": "2009-09",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2013-05-31",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00990769"
    },
    {
      "nct_id": "NCT00857727",
      "title": "Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Agitation",
        "Anesthesia",
        "Pediatrics"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Luke's-Roosevelt Hospital Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Months to 17 Years"
      },
      "enrollment_count": 33,
      "start_date": "2009-08",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2018-11-27",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00857727"
    },
    {
      "nct_id": "NCT02997930",
      "title": "fMRI Connectivity in Fracture Hip Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Delirium",
        "Postoperative Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "fMRI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Montreal Cognitive Assessment (MoCA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Digital Clock Drawing Test Command and Copy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wide Range Achievement Test reading subtest",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hopkins Verbal Learning Test (HVLT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "General Depression Scale (GDS)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "65 Years to 99 Years"
      },
      "enrollment_count": 2,
      "start_date": "2017-01-29",
      "completion_date": "2019-05-06",
      "has_results": false,
      "last_update_posted_date": "2019-08-12",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02997930"
    },
    {
      "nct_id": "NCT00561678",
      "title": "Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Delirium",
        "PD",
        "Postoperative Cognitive Dysfunction",
        "POCD"
      ],
      "interventions": [
        {
          "name": "Precedex (Dexmedetomidine)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "68 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "68 Years and older"
      },
      "enrollment_count": 404,
      "start_date": "2008-02",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2018-04-23",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 10,
      "location_summary": "Miami, Florida • Baltimore, Maryland • College Park, Maryland + 7 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "College Park",
          "state": "Maryland"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00561678"
    },
    {
      "nct_id": "NCT03778372",
      "title": "Methadone for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Emergence Delirium",
        "Strabismus"
      ],
      "interventions": [
        {
          "name": "Methadone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ochsner Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "0 Years to 18 Years"
      },
      "enrollment_count": 55,
      "start_date": "2019-01-01",
      "completion_date": "2020-12-13",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-06-11T03:03:28.630Z",
      "location_count": 1,
      "location_summary": "Jefferson, Louisiana",
      "locations": [
        {
          "city": "Jefferson",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03778372"
    }
  ]
}