{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pre-Cancerous+Dysplasia",
    "query": {
      "condition": "Pre-Cancerous Dysplasia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:38:20.773Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00507182",
      "title": "Spectroscopy for Diagnostic Assessment of Oral Mucosal Lesions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oral Cancer"
      ],
      "interventions": [
        {
          "name": "Fluorescence Spectroscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 381,
      "start_date": "1999-07-02",
      "completion_date": "2018-01-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-19",
      "last_synced_at": "2026-05-22T03:38:20.773Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00507182"
    },
    {
      "nct_id": "NCT06075264",
      "title": "Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vulvar Diseases",
        "HPV Infection",
        "Vulvar HSIL",
        "Pre-Cancerous Dysplasia",
        "HPV Disease",
        "VIN, Usual Type",
        "VIN 2 of Usual Type",
        "VIN 3 of Usual Type",
        "Vin II",
        "Vin III",
        "VIN Grade 2",
        "VIN Grade 3",
        "High Grade Intraepithelial Neoplasia"
      ],
      "interventions": [
        {
          "name": "Artesunate ointment",
          "type": "DRUG"
        },
        {
          "name": "Placebo ointment",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Frantz Viral Therapeutics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 27,
      "start_date": "2023-12-06",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-05-22T03:38:20.773Z",
      "location_count": 5,
      "location_summary": "Fort Myers, Florida • Indianapolis, Indiana • Cleveland, Ohio + 1 more",
      "locations": [
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Mayfield Heights",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06075264"
    },
    {
      "nct_id": "NCT03180684",
      "title": "Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vulvar High Grade Squamous Intraepithelial Lesion (HSIL)",
        "Vulvar Dysplasia",
        "Vulvar Intraepithelial Neoplasia (VIN)",
        "VIN2",
        "VIN3",
        "Pre-cancerous Lesions of the Vulva",
        "Human Papillomavirus (HPV)"
      ],
      "interventions": [
        {
          "name": "VGX-3100",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Imiquimod 5% Cream",
          "type": "DRUG"
        },
        {
          "name": "CELLECTRA™ 2000",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Inovio Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 33,
      "start_date": "2017-08-31",
      "completion_date": "2020-12-18",
      "has_results": true,
      "last_update_posted_date": "2023-08-25",
      "last_synced_at": "2026-05-22T03:38:20.773Z",
      "location_count": 15,
      "location_summary": "Newark, Delaware • Augusta, Georgia • Chicago, Illinois + 12 more",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Scarborough",
          "state": "Maine"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03180684"
    },
    {
      "nct_id": "NCT04098744",
      "title": "Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "CIN 2/3",
        "HPV Infection",
        "Pre-Cancerous Dysplasia",
        "Cervical Dysplasia",
        "HPV Related Disease"
      ],
      "interventions": [
        {
          "name": "Artesunate vaginal insert",
          "type": "DRUG"
        },
        {
          "name": "Placebo vaginal insert",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Frantz Viral Therapeutics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 100 Years · Female only"
      },
      "enrollment_count": 78,
      "start_date": "2020-09-09",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-02",
      "last_synced_at": "2026-05-22T03:38:20.773Z",
      "location_count": 7,
      "location_summary": "Fort Myers, Florida • Ann Arbor, Michigan • Cleveland, Ohio + 2 more",
      "locations": [
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Mayfield Heights",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04098744"
    },
    {
      "nct_id": "NCT00988559",
      "title": "Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HPV16 Positive",
        "Cervical Intraepithelial Neoplasia (CIN 2/3)"
      ],
      "interventions": [
        {
          "name": "DNA vaccination",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Gene gun vaccine",
          "type": "DEVICE"
        },
        {
          "name": "intramuscular vaccination",
          "type": "BIOLOGICAL"
        },
        {
          "name": "intra-lesional vaccine administration",
          "type": "BIOLOGICAL"
        },
        {
          "name": "therapeutic resection of the lesion",
          "type": "PROCEDURE"
        },
        {
          "name": "imiquimod",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE",
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 132,
      "start_date": "2009-09",
      "completion_date": "2016-07",
      "has_results": true,
      "last_update_posted_date": "2018-07-09",
      "last_synced_at": "2026-05-22T03:38:20.773Z",
      "location_count": 3,
      "location_summary": "Birmingham, Alabama • Baltimore, Maryland",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00988559"
    }
  ]
}