{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Preclinical+Alzheimer%27s+Disease",
    "query": {
      "condition": "Preclinical Alzheimer's Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 37,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Preclinical+Alzheimer%27s+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T10:56:49.999Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04928976",
      "title": "Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Preclinical Alzheimer's Disease",
        "Prodromal Alzheimer's Disease",
        "Alzheimer's Disease (Incl Subtypes)",
        "Mild Cognitive Impairment"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Novoic Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 67,
      "start_date": "2021-01-22",
      "completion_date": "2021-07-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-05",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 1,
      "location_summary": "Santa Ana, California",
      "locations": [
        {
          "city": "Santa Ana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04928976"
    },
    {
      "nct_id": "NCT03862222",
      "title": "Atlas of Retinal Imaging in Alzheimer's Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Mild Dementia",
        "Aging",
        "Cognitive Change"
      ],
      "interventions": [
        {
          "name": "Retinal Imaging",
          "type": "OTHER"
        },
        {
          "name": "Pupillometry",
          "type": "OTHER"
        },
        {
          "name": "Contrast Sensitivity",
          "type": "OTHER"
        },
        {
          "name": "Neuropsychological Evaluation",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "APOE genotyping",
          "type": "GENETIC"
        },
        {
          "name": "blood draw",
          "type": "OTHER"
        },
        {
          "name": "Gait Assessment",
          "type": "OTHER"
        },
        {
          "name": "Actigraphy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST",
        "GENETIC"
      ],
      "sponsor": "University of Rhode Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "55 Years to 80 Years"
      },
      "enrollment_count": 165,
      "start_date": "2019-12-16",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-05",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 4,
      "location_summary": "Clearwater, Florida • St. Petersburg, Florida • Kingston, Rhode Island + 1 more",
      "locations": [
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Kingston",
          "state": "Rhode Island"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03862222"
    },
    {
      "nct_id": "NCT07142954",
      "title": "Epidemiology and Biomarker Study in Alzheimer's Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "P-tau217 Test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Eli Lilly and Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "55 Years to 75 Years"
      },
      "enrollment_count": 3400,
      "start_date": "2025-08-25",
      "completion_date": "2033-07",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07142954"
    },
    {
      "nct_id": "NCT04294888",
      "title": "TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Aging"
      ],
      "interventions": [
        {
          "name": "repetitive transcranial magnetic stimulation (rTMS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 4,
      "start_date": "2020-03-02",
      "completion_date": "2021-06-23",
      "has_results": false,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 1,
      "location_summary": "Charlestown, Massachusetts",
      "locations": [
        {
          "city": "Charlestown",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04294888"
    },
    {
      "nct_id": "NCT06033066",
      "title": "Financial Incentives and Recruitment to the APT Webstudy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Dementia",
        "Preclinical Alzheimer's Disease",
        "Prodromal Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Financial Incentives",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Message",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 44844,
      "start_date": "2024-03-01",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 1,
      "location_summary": "Martinez, California",
      "locations": [
        {
          "city": "Martinez",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06033066"
    },
    {
      "nct_id": "NCT06416072",
      "title": "Alzheimer's Plasma Extension",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preclinical Alzheimer's Disease",
        "Early Preclinical Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "NAV4694",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "55 Years to 80 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2023-09-21",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2025-06-10",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 56,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Sun City, Arizona + 48 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06416072"
    },
    {
      "nct_id": "NCT04733989",
      "title": "A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer's Disease (Bio-Hermes)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Alzheimer Disease, Early Onset",
        "Mild Cognitive Impairment",
        "Memory Loss",
        "Memory Disorders",
        "Memory Impairment"
      ],
      "interventions": [
        {
          "name": "Biomarker Data Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "GAP Innovations, PBC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 1002,
      "start_date": "2021-04-21",
      "completion_date": "2022-11-11",
      "has_results": false,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 16,
      "location_summary": "Aventura, Florida • Coral Gables, Florida • Lady Lake, Florida + 13 more",
      "locations": [
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Lady Lake",
          "state": "Florida"
        },
        {
          "city": "Lake Worth",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04733989"
    },
    {
      "nct_id": "NCT06956300",
      "title": "TMS for Cognitive Decline in Aging and Preclinical AD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prodromal Alzheimer's Disease",
        "Preclinical Alzheimer's Disease",
        "Healthy Aging",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Active rTMS",
          "type": "DEVICE"
        },
        {
          "name": "Sham rTMS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "40 Years to 99 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-04-07",
      "completion_date": "2029-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06956300"
    },
    {
      "nct_id": "NCT07516119",
      "title": "Predicting Pre-dementia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mild Cognitive Impairment (MCI)",
        "Alzheimer Dementia (AD)",
        "Alzheimer Disease (AD)",
        "APOE-4 Positive"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Prevention Research Consortium Corp.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-04-15",
      "completion_date": "2029-04-15",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07516119"
    },
    {
      "nct_id": "NCT07413744",
      "title": "The Gut - PRO Study",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Probiotic",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-06",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-06-26T10:56:49.999Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07413744"
    }
  ]
}