{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pregnancy+Trimester%2C+First&page=3",
    "query": {
      "condition": "Pregnancy Trimester, First",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 69,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pregnancy+Trimester%2C+First&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pregnancy+Trimester%2C+First&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T03:08:08.215Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03636451",
      "title": "Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Abortion, Spontaneous",
        "Abortion in First Trimester",
        "Pain Uterus",
        "Abortion Early",
        "Abortion, Missed"
      ],
      "interventions": [
        {
          "name": "40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block",
          "type": "DRUG"
        },
        {
          "name": "20cc 1% lidocaine with 2 units of vasopressin paracervical block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 114,
      "start_date": "2018-10-29",
      "completion_date": "2022-09-27",
      "has_results": true,
      "last_update_posted_date": "2023-04-20",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 2,
      "location_summary": "La Jolla, California • San Diego, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03636451"
    },
    {
      "nct_id": "NCT05320432",
      "title": "Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abortion in First Trimester",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Transcutaneous electrical nerve stimulation (TENS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 70,
      "start_date": "2023-01-20",
      "completion_date": "2024-03-21",
      "has_results": true,
      "last_update_posted_date": "2025-02-25",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05320432"
    },
    {
      "nct_id": "NCT04941443",
      "title": "Methadone and Medication Abortion",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain",
        "Medical Abortion"
      ],
      "interventions": [
        {
          "name": "Methadone Pill",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 4,
      "start_date": "2021-10-04",
      "completion_date": "2022-03-01",
      "has_results": true,
      "last_update_posted_date": "2023-01-23",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04941443"
    },
    {
      "nct_id": "NCT02379494",
      "title": "First Trimester Prediction of Preeclampsia and Fetal Growth Restriction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preeclampsia",
        "Fetal Growth Restriction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Fetal Medicine Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 1200,
      "start_date": "2013-03",
      "completion_date": "2017-01-01",
      "has_results": false,
      "last_update_posted_date": "2017-08-22",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 1,
      "location_summary": "Dayton, Ohio",
      "locations": [
        {
          "city": "Dayton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02379494"
    },
    {
      "nct_id": "NCT02536235",
      "title": "Applied Topical Heat as an Adjunct for Pain Control in First-Trimester Surgical Abortionl",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Topical Heat Application for Intraoperative Abortion Pain Management"
      ],
      "interventions": [
        {
          "name": "heat",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Planned Parenthood of Greater New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "51 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 51 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2015-07",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2016-09-29",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 1,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02536235"
    },
    {
      "nct_id": "NCT06121063",
      "title": "CCT-102 or Expectant Management in Delayed Pregnancy Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Early Pregnancy Loss, Delayed Pregnancy Loss"
      ],
      "interventions": [
        {
          "name": "CCT-102 A and CCT-102 B",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Conceptra Biosciences, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 183,
      "start_date": "2023-07-21",
      "completion_date": "2025-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 15,
      "location_summary": "Tucson, Arizona • San Fernando, California • Panama City, Florida + 12 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "San Fernando",
          "state": "California"
        },
        {
          "city": "Panama City",
          "state": "Florida"
        },
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06121063"
    },
    {
      "nct_id": "NCT05534568",
      "title": "The Oklahoma Parent-Child Assistance Program",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Use Disorders",
        "Pregnancy Related",
        "Alcohol Use Disorder (AUD)",
        "Alcohol Use Complicating Pregnancy, First Trimester",
        "Alcohol Use Complicating Pregnancy, Second Trimester",
        "Alcohol Use Complicating Pregnancy, Third Trimester",
        "Alcohol Use Complicating Pregnancy, Unspecified Trimester",
        "Alcohol Use Complicating Pregnancy, Childbirth, and the Puerperium",
        "Fetal Alcohol Spectrum Disorders",
        "Fetal Alcohol Syndrome",
        "Drug Use Disorders",
        "Drug Use Complicating Pregnancy, First Trimester",
        "Drug Use Complicating Pregnancy, Second Trimester",
        "Drug Use Complicating Pregnancy, Third Trimester",
        "Drug Use Complicating Pregnancy, Unspecified Trimester",
        "Drug Use Complicating Pregnancy, Childbirth, and the Puerperium",
        "Maternal Drugs Affecting Fetus"
      ],
      "interventions": [
        {
          "name": "Parent-Child Assistance Program",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2022-11-15",
      "completion_date": "2026-11-15",
      "has_results": false,
      "last_update_posted_date": "2024-06-07",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 2,
      "location_summary": "Oklahoma City, Oklahoma • Tulsa, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05534568"
    },
    {
      "nct_id": "NCT06952439",
      "title": "Clinical Performance Evaluation of the Artificial Intelligence (AI)/ Machine Learning (ML) Technologies Utilized by the Origin Medical EXAM ASSISTANT",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "To Validate the Clinical Performance of AI/ML Technologies in First-trimester Pregnant Participants",
        "First Trimester Pregnancy"
      ],
      "interventions": [
        {
          "name": "Images and cines captured through the capture card (ICC)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Origin Medical Systems, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 551,
      "start_date": "2025-03-19",
      "completion_date": "2025-05-19",
      "has_results": false,
      "last_update_posted_date": "2025-10-21",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 15,
      "location_summary": "Apple Valley, California • Indio, California • Murrieta, California + 12 more",
      "locations": [
        {
          "city": "Apple Valley",
          "state": "California"
        },
        {
          "city": "Indio",
          "state": "California"
        },
        {
          "city": "Murrieta",
          "state": "California"
        },
        {
          "city": "Redlands",
          "state": "California"
        },
        {
          "city": "Riverside",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06952439"
    },
    {
      "nct_id": "NCT00006445",
      "title": "Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Down Syndrome",
        "Chromosome Abnormalities"
      ],
      "interventions": [
        {
          "name": "Ultrasound",
          "type": "PROCEDURE"
        },
        {
          "name": "Serum screen",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 45 Years · Female only"
      },
      "enrollment_count": 38000,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2007-02-22",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 10,
      "location_summary": "Denver, Colorado • Boston, Massachusetts • Royal Oak, Michigan + 6 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006445"
    },
    {
      "nct_id": "NCT04056637",
      "title": "Choice of Modality of Follow up for Medication Abortion",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abortion in First Trimester"
      ],
      "interventions": [
        {
          "name": "Choice of follow-up option",
          "type": "OTHER"
        },
        {
          "name": "Multi-level pregnancy test",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 26,
      "start_date": "2019-09-09",
      "completion_date": "2020-03-31",
      "has_results": false,
      "last_update_posted_date": "2020-05-28",
      "last_synced_at": "2026-10-21T03:08:08.215Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04056637"
    }
  ]
}