{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Premenstrual+Syndrome",
    "query": {
      "condition": "Premenstrual Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 42,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Premenstrual+Syndrome&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:47:11.748Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00005119",
      "title": "Altered Calcium and Vitamin D in PMDD or Severe PMS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "Measures of calcium and bone turnover",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": null,
      "start_date": "2000-05",
      "completion_date": "2003-10",
      "has_results": false,
      "last_update_posted_date": "2010-03-02",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005119"
    },
    {
      "nct_id": "NCT00536198",
      "title": "Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder"
      ],
      "interventions": [
        {
          "name": "Sertraline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "48 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 48 Years · Female only"
      },
      "enrollment_count": 252,
      "start_date": "2007-11-06",
      "completion_date": "2012-02",
      "has_results": true,
      "last_update_posted_date": "2017-04-14",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 3,
      "location_summary": "New Haven, Connecticut • New York, New York • Richmond, Virginia",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00536198"
    },
    {
      "nct_id": "NCT05237661",
      "title": "Study to Evaluate Your Super's Moon Balance and Its Impact on Premenstrual Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PMS",
        "Menstrual Discomfort",
        "Menstrual Pain"
      ],
      "interventions": [
        {
          "name": "Moon Balance",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Your Super, INC.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2022-02-15",
      "completion_date": "2022-05-31",
      "has_results": false,
      "last_update_posted_date": "2022-06-21",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05237661"
    },
    {
      "nct_id": "NCT00523705",
      "title": "Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "PMS"
      ],
      "interventions": [
        {
          "name": "escitalopram",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "19 Years",
        "sex": "FEMALE",
        "summary": "15 Years to 19 Years · Female only"
      },
      "enrollment_count": 11,
      "start_date": "2008-02",
      "completion_date": "2009-10",
      "has_results": true,
      "last_update_posted_date": "2014-06-06",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00523705"
    },
    {
      "nct_id": "NCT06771583",
      "title": "Identification and Validation of Epigenetic Biomarkers of PMDD",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PMDD",
        "Premenstrual Dysphoric Disorder (PMDD)",
        "Premenstrual Syndrome-PMS",
        "Premenstrual Syndrome",
        "Menstrual Cycle"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 500,
      "start_date": "2025-09-12",
      "completion_date": "2031-02-15",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06771583"
    },
    {
      "nct_id": "NCT01799733",
      "title": "Alternative Treatments for Premenstrual Dysphoric Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder"
      ],
      "interventions": [
        {
          "name": "LWT+AM BWL",
          "type": "OTHER"
        },
        {
          "name": "EWT+PM BWL",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 43,
      "start_date": "2013-06-18",
      "completion_date": "2018-07-03",
      "has_results": false,
      "last_update_posted_date": "2022-02-04",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01799733"
    },
    {
      "nct_id": "NCT00678574",
      "title": "The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder",
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "fluoxetine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "1998-03",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2018-07-27",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00678574"
    },
    {
      "nct_id": "NCT07217418",
      "title": "Music Therapy and Its Effects on Premenstrual Syndrome (PMS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome",
        "Menstrual Symptoms"
      ],
      "interventions": [
        {
          "name": "Music Listening Group (LG)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Participant-Selected Songs for the Interactive Singing Intervention Group (SG)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Participant-Selected Songs for the Interactive Instrumental Playing Group (PG)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "West Chester University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 20,
      "start_date": "2024-02-01",
      "completion_date": "2024-06-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "Scranton, Pennsylvania",
      "locations": [
        {
          "city": "Scranton",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07217418"
    },
    {
      "nct_id": "NCT01912391",
      "title": "Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Borderline Personality Disorder"
      ],
      "interventions": [
        {
          "name": "Selegiline",
          "type": "DRUG"
        },
        {
          "name": "Placebo (for Selegiline)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mood and Anxiety Research, Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2012-10",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2015-10-08",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "Fresno, California",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01912391"
    },
    {
      "nct_id": "NCT07018479",
      "title": "Effects of a Female Hormone Balance Supplement on Premenstrual Syndrome Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "FemmeBalance Supplement Group",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "VINABAS FORMULATIONS SL",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2024-07-30",
      "completion_date": "2025-01-20",
      "has_results": false,
      "last_update_posted_date": "2025-06-12",
      "last_synced_at": "2026-05-22T07:47:11.748Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07018479"
    }
  ]
}