{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Premenstrual+Syndrome&page=2",
    "query": {
      "condition": "Premenstrual Syndrome",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Premenstrual+Syndrome&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-13T13:18:25.132Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07084714",
      "title": "Moderate Aerobic Exercise for Managing Menstrual Cycle Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome",
        "Menstrual Cycle",
        "Menstrual Distress (Dysmenorrhea)",
        "Menstrual Bleeding, Heavy"
      ],
      "interventions": [
        {
          "name": "Moderate Aerobic Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Colorado Springs",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 35,
      "start_date": "2025-07",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "Colorado Springs, Colorado",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07084714"
    },
    {
      "nct_id": "NCT05900024",
      "title": "A Study to Evaluate the Effect of Funk It Cycle Bites on PMS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "Funk It Cycle Bites",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Funk It Wellness",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2023-05-01",
      "completion_date": "2023-10-01",
      "has_results": false,
      "last_update_posted_date": "2024-02-29",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05900024"
    },
    {
      "nct_id": "NCT05237661",
      "title": "Study to Evaluate Your Super's Moon Balance and Its Impact on Premenstrual Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PMS",
        "Menstrual Discomfort",
        "Menstrual Pain"
      ],
      "interventions": [
        {
          "name": "Moon Balance",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Your Super, INC.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2022-02-15",
      "completion_date": "2022-05-31",
      "has_results": false,
      "last_update_posted_date": "2022-06-21",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05237661"
    },
    {
      "nct_id": "NCT00536198",
      "title": "Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder"
      ],
      "interventions": [
        {
          "name": "Sertraline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "48 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 48 Years · Female only"
      },
      "enrollment_count": 252,
      "start_date": "2007-11-06",
      "completion_date": "2012-02",
      "has_results": true,
      "last_update_posted_date": "2017-04-14",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 3,
      "location_summary": "New Haven, Connecticut • New York, New York • Richmond, Virginia",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00536198"
    },
    {
      "nct_id": "NCT00678574",
      "title": "The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder",
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "fluoxetine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "1998-03",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2018-07-27",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00678574"
    },
    {
      "nct_id": "NCT00518570",
      "title": "Levetiracetam in the Treatment of Patients With Premenstrual Dysphoric Disorder (PMDD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder"
      ],
      "interventions": [
        {
          "name": "Levetiracetam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Berkshire Health Systems",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 7,
      "start_date": "2003-11",
      "completion_date": "2006-10",
      "has_results": false,
      "last_update_posted_date": "2007-08-20",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "Pittsfield, Massachusetts",
      "locations": [
        {
          "city": "Pittsfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00518570"
    },
    {
      "nct_id": "NCT06018168",
      "title": "An RCT Evaluating the Efficacy of a Skincare Routine and Acne Supplement on Improving Acne and Other Symptoms of PMS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acne",
        "Premenstrual Syndrome"
      ],
      "interventions": [
        {
          "name": "Skincare Routine",
          "type": "OTHER"
        },
        {
          "name": "MINDBODYSKIN Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Clearstem Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2023-06-30",
      "completion_date": "2024-01-10",
      "has_results": false,
      "last_update_posted_date": "2024-02-22",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06018168"
    },
    {
      "nct_id": "NCT03862469",
      "title": "Premenstrual Hormonal and Affective State Evaluation (PHASE) Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder"
      ],
      "interventions": [
        {
          "name": "Individualized laboratory test",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 129,
      "start_date": "2019-09-26",
      "completion_date": "2023-09-01",
      "has_results": true,
      "last_update_posted_date": "2025-04-24",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03862469"
    },
    {
      "nct_id": "NCT06704594",
      "title": "Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder (PMDD)"
      ],
      "interventions": [
        {
          "name": "sertraline 50 mg daily",
          "type": "DRUG"
        },
        {
          "name": "Placebo Oral Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 288,
      "start_date": "2025-05-14",
      "completion_date": "2029-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Charlottesville, Virginia",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06704594"
    },
    {
      "nct_id": "NCT01799733",
      "title": "Alternative Treatments for Premenstrual Dysphoric Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder"
      ],
      "interventions": [
        {
          "name": "LWT+AM BWL",
          "type": "OTHER"
        },
        {
          "name": "EWT+PM BWL",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 43,
      "start_date": "2013-06-18",
      "completion_date": "2018-07-03",
      "has_results": false,
      "last_update_posted_date": "2022-02-04",
      "last_synced_at": "2026-06-13T13:18:25.132Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01799733"
    }
  ]
}