{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Prescription+Opioid+Dependence",
    "query": {
      "condition": "Prescription Opioid Dependence"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 21,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Prescription+Opioid+Dependence&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T22:28:11.919Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00555425",
      "title": "Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opiate Dependence"
      ],
      "interventions": [
        {
          "name": "Behavioral: Buprenorphine/naloxone maintenance (Mtn)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral: Buprenorphine/naloxone detoxification (Dtx)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 113,
      "start_date": "2008-07",
      "completion_date": "2013-05",
      "has_results": true,
      "last_update_posted_date": "2019-01-14",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00555425"
    },
    {
      "nct_id": "NCT03726476",
      "title": "Expectations and Pain Control Advancement In surgeRy: The REPAIR Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abuses Over-The-Counter/Prescription Medications",
        "Pain, Postoperative",
        "Opioid Use",
        "Physical Activity",
        "Patient Dependence on"
      ],
      "interventions": [
        {
          "name": "Patient centered pre-op education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "routine preop education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 174,
      "start_date": "2019-09-10",
      "completion_date": "2021-12-06",
      "has_results": true,
      "last_update_posted_date": "2024-07-18",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 2,
      "location_summary": "Albuquerque, New Mexico • Rio Rancho, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        },
        {
          "city": "Rio Rancho",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03726476"
    },
    {
      "nct_id": "NCT04069403",
      "title": "An Opioid Prescribing Nudge",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use, Unspecified",
        "Prescription Drug Abuse (Not Dependent)",
        "Prescription Drug Abuse and Dependency",
        "Health Behavior",
        "Benzodiazepine Abuse",
        "Benzodiazepine Dependent"
      ],
      "interventions": [
        {
          "name": "Automated Reports on prescription patterns for their patients",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 427,
      "start_date": "2019-09-10",
      "completion_date": "2020-06-15",
      "has_results": false,
      "last_update_posted_date": "2020-06-30",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04069403"
    },
    {
      "nct_id": "NCT00719095",
      "title": "Effective Treatment for Prescription Opioid Abuse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prescription Opioid Dependence"
      ],
      "interventions": [
        {
          "name": "buprenorphine taper followed by naltrexone maintenance",
          "type": "DRUG"
        },
        {
          "name": "Behavioral therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Vermont Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 105,
      "start_date": "2006-04",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2013-04-15",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00719095"
    },
    {
      "nct_id": "NCT04469868",
      "title": "No Opioids PrescrIptions On Discharge After Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use",
        "Prescription Drug Abuse and Dependency",
        "Surgery",
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "No opioids at discharge",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 350,
      "start_date": "2018-12-15",
      "completion_date": "2024-04-01",
      "has_results": false,
      "last_update_posted_date": "2024-07-31",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04469868"
    },
    {
      "nct_id": "NCT03377855",
      "title": "Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use",
        "Opioid-Related Disorders",
        "Opioid Abuse",
        "Prescription Drug Abuse and Dependency"
      ],
      "interventions": [
        {
          "name": "Default Prescribing Change",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 948,
      "start_date": "2018-02-01",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-02-24",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03377855"
    },
    {
      "nct_id": "NCT01740414",
      "title": "Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Opioid Abuse",
        "Opioid Dependence"
      ],
      "interventions": [
        {
          "name": "MN-166 (50 mg) First",
          "type": "DRUG"
        },
        {
          "name": "Placebo First",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 28,
      "start_date": "2012-11",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2017-08-17",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01740414"
    },
    {
      "nct_id": "NCT04811014",
      "title": "Young Houston Emergency Opioid Engagement System",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Opioid Dependence",
        "Opioid Overdose",
        "Opioid Use",
        "Substance Use Disorders"
      ],
      "interventions": [
        {
          "name": "Buprenorphine, Naloxone Drug Combination",
          "type": "DRUG"
        },
        {
          "name": "Individual Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Peer Recovery Support Services",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support Group",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Referral to Medication Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Assertive Outreach",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 250,
      "start_date": "2021-04-19",
      "completion_date": "2030-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04811014"
    },
    {
      "nct_id": "NCT02660606",
      "title": "A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Opioid-Related Disorders",
        "Opiate Addiction",
        "Narcotic Abuse",
        "Drug Abuse"
      ],
      "interventions": [
        {
          "name": "Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Member Companies of the Opioid PMR Consortium",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2015-01-02",
      "completion_date": "2016-01-18",
      "has_results": false,
      "last_update_posted_date": "2020-04-15",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02660606"
    },
    {
      "nct_id": "NCT02282306",
      "title": "Phone Interview to Prevent Recurring Opioid Overdoses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overdose",
        "Opioid-related Disorders",
        "Drug Addiction",
        "Drug Abuse",
        "Substance Abuse",
        "Opioid Use, Unspecified",
        "Opioid Dependence",
        "Drug Overdose"
      ],
      "interventions": [
        {
          "name": "TTIP-PRO",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2014-09",
      "completion_date": "2015-02",
      "has_results": false,
      "last_update_posted_date": "2015-05-28",
      "last_synced_at": "2026-07-23T22:28:11.919Z",
      "location_count": 2,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02282306"
    }
  ]
}