{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Preterm+Birth+Recurrence",
    "query": {
      "condition": "Preterm Birth Recurrence"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:05:07.004Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06004674",
      "title": "Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Adverse Pregnancy Outcome"
      ],
      "interventions": [
        {
          "name": "Lovenox 40mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2023-12-26",
      "completion_date": "2026-03",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 1,
      "location_summary": "Evanston, Illinois",
      "locations": [
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06004674"
    },
    {
      "nct_id": "NCT06980025",
      "title": "Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Preterm Delivery",
        "Obstetrical Complications"
      ],
      "interventions": [
        {
          "name": "162mg Aspirin",
          "type": "DRUG"
        },
        {
          "name": "81mg Aspirin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The George Washington University Biostatistics Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "14 Years and older · Female only"
      },
      "enrollment_count": 1800,
      "start_date": "2025-07-01",
      "completion_date": "2029-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 14,
      "location_summary": "Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 10 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06980025"
    },
    {
      "nct_id": "NCT01180296",
      "title": "Oral Progesterone for Prevention of Preterm Birth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "oral micronized progesterone",
          "type": "DRUG"
        },
        {
          "name": "Identical Placebo tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Fetal Medicine Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 36,
      "start_date": "2006-11",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2019-02-18",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 1,
      "location_summary": "Dayton, Ohio",
      "locations": [
        {
          "city": "Dayton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01180296"
    },
    {
      "nct_id": "NCT04663607",
      "title": "Mobile Strategy to Reduce the Risk of Recurrent Preterm Birth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Use of PretermConnect App",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 50 Years · Female only"
      },
      "enrollment_count": 221,
      "start_date": "2021-10-07",
      "completion_date": "2025-07-18",
      "has_results": false,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04663607"
    },
    {
      "nct_id": "NCT02913495",
      "title": "Vaginal Versus Intramuscular Progesterone for the Prevention of Recurrent Preterm Birth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "Vaginal Progesterone",
          "type": "DRUG"
        },
        {
          "name": "Intramuscular Progesterone (17 alpha hydroxprogesterone caproate)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 210,
      "start_date": "2016-09",
      "completion_date": "2021-09",
      "has_results": true,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Springfield, Massachusetts • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Springfield",
          "state": "Massachusetts"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02913495"
    },
    {
      "nct_id": "NCT06915428",
      "title": "Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Birth Complication",
        "Preterm Birth",
        "Preterm Birth Recurrence",
        "Preeclampsia",
        "Preeclampsia (PE)",
        "Hypertensive Disorders of Pregnancy",
        "Support Program",
        "Stress",
        "Resilience, Psychological",
        "Empowerment, Patient",
        "Emotional Stress",
        "Pregnancy",
        "Pregnancy Complications",
        "Pregnancy Induced Hypertension",
        "Neonates and Preterm Infants",
        "Cervical Insufficiency",
        "Social Determinants of Health (SDOH)",
        "Cervical Shortening",
        "Disparities in Pregnancy Complications",
        "Disparities",
        "Prenatal Care",
        "Care Coordination"
      ],
      "interventions": [
        {
          "name": "Care coordination",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic massage",
          "type": "BEHAVIORAL"
        },
        {
          "name": "support gift #1",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support gift #2",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support gift #3",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support gift #4",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Additional PTBCARE+ support",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress reduction toolkit - Visit 1 (V1)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PTBCARE+ mobile application (app) and website",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep, meditation, and Wellness app",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Emergency low blood sugar kit",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low dose aspirin (LDA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Visit #2 Stress Reduction Toolkit",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1228,
      "start_date": "2026-02-01",
      "completion_date": "2029-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06915428"
    },
    {
      "nct_id": "NCT01864629",
      "title": "Optimizing Postpartum Contraception in Women With Preterm Births",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Method of Contraception",
        "Preterm Birth Recurrence"
      ],
      "interventions": [
        {
          "name": "Focused contraception counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 50 Years · Female only"
      },
      "enrollment_count": 134,
      "start_date": "2013-04",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2017-10-26",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01864629"
    },
    {
      "nct_id": "NCT01004029",
      "title": "Confirmatory Study of 17P vs Vehicle for Prevention of Preterm Birth in Women w/ Previous Spontaneous Preterm Delivery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Hydroxyprogesterone Caproate Injection (HPC), 250mg/mL",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AMAG Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1740,
      "start_date": "2009-10",
      "completion_date": "2018-10",
      "has_results": true,
      "last_update_posted_date": "2022-06-01",
      "last_synced_at": "2026-05-22T04:05:07.004Z",
      "location_count": 41,
      "location_summary": "Montgomery, Alabama • Tucson, Arizona • La Mesa, California + 35 more",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "West Hills",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01004029"
    }
  ]
}