{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Preterm+Premature+Rupture+of+Fetal+Membranes&page=2",
    "query": {
      "condition": "Preterm Premature Rupture of Fetal Membranes",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Preterm+Premature+Rupture+of+Fetal+Membranes&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T21:34:36.559Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01852188",
      "title": "Intrapartum Study of Sterile and Clean Gloves",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chorioamnionitis"
      ],
      "interventions": [
        {
          "name": "Type of glove used for intrapartum vaginal exams",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 507,
      "start_date": "2011-05",
      "completion_date": "2014-11-02",
      "has_results": false,
      "last_update_posted_date": "2018-05-18",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01852188"
    },
    {
      "nct_id": "NCT05893485",
      "title": "Physiological and Psychological Effects of Music Therapy in the Pregnant Woman and Fetus",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Music Therapy",
        "Preterm Premature Rupture of Membrane (PPROM)"
      ],
      "interventions": [
        {
          "name": "Music Therapy Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Christina Chianis Reed",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2023-05-15",
      "completion_date": "2026-03-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05893485"
    },
    {
      "nct_id": "NCT06273891",
      "title": "Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Premature Rupture of Membrane"
      ],
      "interventions": [
        {
          "name": "Erythromycin",
          "type": "DRUG"
        },
        {
          "name": "Azithromycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Inova Health Care Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 140,
      "start_date": "2024-03-08",
      "completion_date": "2026-10-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 2,
      "location_summary": "Falls Church, Virginia • Norfolk, Virginia",
      "locations": [
        {
          "city": "Falls Church",
          "state": "Virginia"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06273891"
    },
    {
      "nct_id": "NCT00153517",
      "title": "Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vaginosis, Bacterial",
        "Premature Birth",
        "Birth Weight",
        "Chorioamnionitis"
      ],
      "interventions": [
        {
          "name": "oral versus vaginal metronidazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Centers for Disease Control and Prevention",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "16 Years and older · Female only"
      },
      "enrollment_count": 126,
      "start_date": "1999-10",
      "completion_date": "2004-09",
      "has_results": false,
      "last_update_posted_date": "2024-05-29",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00153517"
    },
    {
      "nct_id": "NCT00185991",
      "title": "Comparison of Once Daily Versus 8 Hour Dosing of Gentamicin for the Treatment of Intrapartum Chorioamnionitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chorioamnionitis"
      ],
      "interventions": [
        {
          "name": "gentamicin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 126,
      "start_date": "2004-06",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2011-06-15",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00185991"
    },
    {
      "nct_id": "NCT02997345",
      "title": "PPROM Registry (Preterm Premature Rupture of Membranes)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fetal Membranes, Premature Rupture",
        "Preterm Premature Rupture of the Membranes",
        "Oligohydramnios",
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "There is no intervention associated with this study.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "American Alliance for pProm Support",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 55 Years · Female only"
      },
      "enrollment_count": 3000,
      "start_date": "2013-07",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02997345"
    },
    {
      "nct_id": "NCT06074601",
      "title": "MIRACLE of LIFE Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preterm Labor",
        "Preterm Birth",
        "Preterm Birth Complication",
        "Preterm Premature Rupture of Membrane",
        "Preeclampsia",
        "HELLP",
        "Gestational Hypertension",
        "Gestational Diabetes Mellitus in Pregnancy",
        "Small for Gestational Age at Delivery",
        "Intrauterine Growth Restriction"
      ],
      "interventions": [
        {
          "name": "Mirvie Predictive Test for Adverse Pregnancy Outcomes",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mirvie",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 10000,
      "start_date": "2021-08-01",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-27",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 10,
      "location_summary": "San Diego, California • Orlando, Florida • New Orleans, Louisiana + 7 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06074601"
    },
    {
      "nct_id": "NCT00201656",
      "title": "Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fetal Membranes, Premature Rupture"
      ],
      "interventions": [
        {
          "name": "Retention of Cerclage",
          "type": "PROCEDURE"
        },
        {
          "name": "Removal of Cerclage",
          "type": "PROCEDURE"
        },
        {
          "name": "Removal vs. Retention of Cervical Cerclage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Obstetrix Medical Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 58,
      "start_date": "2004-11",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2014-12-19",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 23,
      "location_summary": "Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 18 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00201656"
    },
    {
      "nct_id": "NCT04294069",
      "title": "Azithromycin Dose and PPROM Treatment: a Pilot Randomized Controlled Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preterm Premature Rupture of Membrane"
      ],
      "interventions": [
        {
          "name": "Azithromycin 500 mg",
          "type": "DRUG"
        },
        {
          "name": "Azithromycin Oral Product",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 65 Years · Female only"
      },
      "enrollment_count": 6,
      "start_date": "2020-09-14",
      "completion_date": "2021-04-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04294069"
    },
    {
      "nct_id": "NCT03168178",
      "title": "Intrapartum Fever: Antibiotics Versus no Treatment",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chorioamnionitis",
        "Intrapartum Fever",
        "Intra-amniotic Infection"
      ],
      "interventions": [
        {
          "name": "Standard Antibiotic Treatment",
          "type": "DRUG"
        },
        {
          "name": "No Antibiotic Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2017-06-08",
      "completion_date": "2018-07-26",
      "has_results": false,
      "last_update_posted_date": "2018-10-23",
      "last_synced_at": "2026-07-23T21:34:36.559Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03168178"
    }
  ]
}