{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Prevention+of+Surgical+Site+Infections",
    "query": {
      "condition": "Prevention of Surgical Site Infections"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 52,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Prevention+of+Surgical+Site+Infections&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T08:32:03.347Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02390401",
      "title": "Vacuum Assisted Closure for Cesarean Section",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Surgical Wound Infection"
      ],
      "interventions": [
        {
          "name": "Vacuum-assisted closure",
          "type": "DEVICE"
        },
        {
          "name": "Standard sterile dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 166,
      "start_date": "2015-05",
      "completion_date": "2017-09",
      "has_results": false,
      "last_update_posted_date": "2018-05-22",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 4,
      "location_summary": "Lebanon, New Hampshire • Nashua, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "Nashua",
          "state": "New Hampshire"
        },
        {
          "city": "Nashua",
          "state": "New Hampshire"
        },
        {
          "city": "Nashua",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02390401"
    },
    {
      "nct_id": "NCT02385708",
      "title": "Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "2% Chlorohexidine Gluconate Standard of Care",
          "type": "DRUG"
        },
        {
          "name": "2% Chlorohexidine Gluconate Chin to Toe",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 163,
      "start_date": "2015-08",
      "completion_date": "2018-06-21",
      "has_results": true,
      "last_update_posted_date": "2019-04-30",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02385708"
    },
    {
      "nct_id": "NCT05920122",
      "title": "Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Surgical Site Infection",
        "Cesarean Section; Infection"
      ],
      "interventions": [
        {
          "name": "2% Chlorhexidine gluconate with 70% alcohol",
          "type": "DRUG"
        },
        {
          "name": "4% Chlorhexidine Gluconate aqueous solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hyagriv Simhan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 1398,
      "start_date": "2023-10-09",
      "completion_date": "2025-10-17",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05920122"
    },
    {
      "nct_id": "NCT01046981",
      "title": "Tumescent Antibiotic Delivery Pharmacokinetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Prevention of Surgical Site Infections"
      ],
      "interventions": [
        {
          "name": "Tumescent Antibiotic Delivery of cefazolin with or without metronidazole",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous Antibiotic Delivery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Klein, Jeffrey A., M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 4,
      "start_date": "2009-03",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2011-09-28",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 1,
      "location_summary": "San Juan Capistrano, California",
      "locations": [
        {
          "city": "San Juan Capistrano",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01046981"
    },
    {
      "nct_id": "NCT03483363",
      "title": "Topical Antibiotic Irrigation (Gentamicin) in Prophylaxis of Midfacial Fracture Surgical Wounds",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "topical irrigation with gentamicin (80mg diluted in 1L 0.9% normal saline)",
          "type": "DRUG"
        },
        {
          "name": "topical irrigation with sterile normal saline (NS)",
          "type": "DRUG"
        },
        {
          "name": "intravenous (IV) prophylactic antibiotic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2018-10-09",
      "completion_date": "2022-01-02",
      "has_results": true,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03483363"
    },
    {
      "nct_id": "NCT04597008",
      "title": "Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post Operative Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "Treatment group",
          "type": "DRUG"
        },
        {
          "name": "Control group",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Major Extremity Trauma Research Consortium",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1660,
      "start_date": "2021-06-18",
      "completion_date": "2025-07-30",
      "has_results": true,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 41,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Redwood City, California + 35 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "West Hollywood",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04597008"
    },
    {
      "nct_id": "NCT03560232",
      "title": "Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Open Fracture",
        "Post-Op Wound Infection"
      ],
      "interventions": [
        {
          "name": "Ceftriaxone",
          "type": "DRUG"
        },
        {
          "name": "Ampicillin/sulbactam",
          "type": "DRUG"
        },
        {
          "name": "Piperacillin/tazobactam",
          "type": "DRUG"
        },
        {
          "name": "Cefazolin + Gentamicin",
          "type": "DRUG"
        },
        {
          "name": "Clindamycin + Gentamicin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mercy Health Ohio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2018-07-09",
      "completion_date": "2020-02-19",
      "has_results": false,
      "last_update_posted_date": "2020-09-11",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 2,
      "location_summary": "Warren, Ohio • Youngstown, Ohio",
      "locations": [
        {
          "city": "Warren",
          "state": "Ohio"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03560232"
    },
    {
      "nct_id": "NCT06791993",
      "title": "Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dysbiosis",
        "Gut -microbiota",
        "Microbiome Analysis",
        "Probiotic",
        "Antibiotic Prophylaxis"
      ],
      "interventions": [
        {
          "name": "Placebo Capsule",
          "type": "DRUG"
        },
        {
          "name": "Probiotic with Human Milk Oligosaccharides (HMO)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Acibadem Maslak Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-02-01",
      "completion_date": "2025-10-01",
      "has_results": false,
      "last_update_posted_date": "2025-01-24",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06791993"
    },
    {
      "nct_id": "NCT06702878",
      "title": "Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgical Site Infections",
        "Surgical Wound Infection",
        "Infections",
        "Anti-Infective Agents"
      ],
      "interventions": [
        {
          "name": "nasal antimicrobial photodisinfection therapy",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Ondine Biomedical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4787,
      "start_date": "2024-12-27",
      "completion_date": "2026-05-07",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 14,
      "location_summary": "Englewood, Colorado • Brandon, Florida • Largo, Florida + 9 more",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Brandon",
          "state": "Florida"
        },
        {
          "city": "Largo",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Trinity",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06702878"
    },
    {
      "nct_id": "NCT03982810",
      "title": "The Role of Guideline-adherent Perioperative Antibiotic Administration and the Risk of Surgical Site Infections After Non-cardiac Surgery.",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Surgical Site Infection",
        "Antibiotic Prophylaxis"
      ],
      "interventions": [
        {
          "name": "Antibiotics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-06-01",
      "completion_date": "2024-03",
      "has_results": false,
      "last_update_posted_date": "2022-07-25",
      "last_synced_at": "2026-07-24T08:32:03.347Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03982810"
    }
  ]
}