{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Primary+Hyperoxaluria+Type+1&page=2",
    "query": {
      "condition": "Primary Hyperoxaluria Type 1",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Primary+Hyperoxaluria+Type+1&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T23:22:52.909Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03905694",
      "title": "A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Primary Hyperoxaluria",
        "Primary Hyperoxaluria Type 1 (PH1)"
      ],
      "interventions": [
        {
          "name": "Lumasiran",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "0 Years to 5 Years"
      },
      "enrollment_count": 18,
      "start_date": "2019-04-22",
      "completion_date": "2024-07-26",
      "has_results": true,
      "last_update_posted_date": "2025-02-14",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • Houston, Texas",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03905694"
    },
    {
      "nct_id": "NCT05001269",
      "title": "Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Primary Hyperoxaluria",
        "Primary Hyperoxaluria Type 1",
        "Primary Hyperoxaluria Type 2",
        "Primary Hyperoxaluria Type 3"
      ],
      "interventions": [
        {
          "name": "nedosiran",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dicerna Pharmaceuticals, Inc., a Novo Nordisk company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "Up to 11 Years"
      },
      "enrollment_count": 27,
      "start_date": "2022-02-22",
      "completion_date": "2025-02-05",
      "has_results": true,
      "last_update_posted_date": "2026-04-16",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05001269"
    },
    {
      "nct_id": "NCT03391804",
      "title": "Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Enteric Hyperoxaluria",
        "Primary Hyperoxaluria",
        "Hyperoxalemia"
      ],
      "interventions": [
        {
          "name": "ALLN-177",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allena Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2018-07-17",
      "completion_date": "2019-12-13",
      "has_results": false,
      "last_update_posted_date": "2020-12-30",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 4,
      "location_summary": "Scottsdale, Arizona • Little Rock, Arkansas • New Haven, Connecticut + 1 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03391804"
    },
    {
      "nct_id": "NCT02124395",
      "title": "Health-related Quality of Life in Rare Kidney Stone",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Hyperoxaluria",
        "Cystinuria",
        "Adenine Phosphoribosyl Transferase Deficiency",
        "Dent Disease"
      ],
      "interventions": [
        {
          "name": "Health-related Quality of Life in Rare Kidney Stone Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 365,
      "start_date": "2013-08",
      "completion_date": "2022-07",
      "has_results": false,
      "last_update_posted_date": "2022-09-02",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • New York, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02124395"
    },
    {
      "nct_id": "NCT04152200",
      "title": "A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Primary Hyperoxaluria Type 1",
        "Primary Hyperoxaluria"
      ],
      "interventions": [
        {
          "name": "Lumasiran",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 21,
      "start_date": "2020-01-21",
      "completion_date": "2025-06-23",
      "has_results": true,
      "last_update_posted_date": "2025-07-18",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • Houston, Texas",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04152200"
    },
    {
      "nct_id": "NCT04982393",
      "title": "BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Hyperoxaluria Type 1"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 207,
      "start_date": "2021-12-13",
      "completion_date": "2028-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Washington D.C., District of Columbia • Boston, Massachusetts + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04982393"
    },
    {
      "nct_id": "NCT00875823",
      "title": "International Registry for Primary Hyperoxaluria",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Hyperoxaluria",
        "Nephrocalcinosis",
        "Kidney Stones"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2003-09",
      "completion_date": "2009-07",
      "has_results": false,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • Sacramento, California • Chicago, Illinois + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00875823"
    },
    {
      "nct_id": "NCT00588562",
      "title": "Rare Kidney Stone Consortium Patient Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Hyperoxaluria",
        "Dent Disease",
        "Cystinuria",
        "APRT Deficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "0 Years to 100 Years"
      },
      "enrollment_count": 730,
      "start_date": "2003-07",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-04",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 3,
      "location_summary": "Rochester, Minnesota • New York, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00588562"
    },
    {
      "nct_id": "NCT02026388",
      "title": "Rare Kidney Stone Consortium Biobank",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Hyperoxaluria",
        "Dent Disease",
        "APRT Deficiency",
        "Cystinuria"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2000,
      "start_date": "2013-05",
      "completion_date": "2030-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-22",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02026388"
    },
    {
      "nct_id": "NCT04542590",
      "title": "Natural History of Patients With PH3 and a History of Stone Events",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Hyperoxaluria Type 3"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dicerna Pharmaceuticals, Inc., a Novo Nordisk company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2021-09-09",
      "completion_date": "2024-07-23",
      "has_results": false,
      "last_update_posted_date": "2024-12-02",
      "last_synced_at": "2026-05-21T23:22:52.909Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • New York, New York",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04542590"
    }
  ]
}