{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Primary+Hypertension&page=2",
    "query": {
      "condition": "Primary Hypertension",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Primary+Hypertension&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T03:10:31.877Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00098072",
      "title": "Endothelial Cell Dysfunction in Pulmonary Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Secondary Pulmonary Arterial Hypertension"
      ],
      "interventions": [
        {
          "name": "Heart Catheterization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 27,
      "start_date": "2000-05-17",
      "completion_date": "2009-07-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00098072"
    },
    {
      "nct_id": "NCT01408472",
      "title": "NT-501 CNTF Implant for Glaucoma: Safety, Neuroprotection and Neuroenhancement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Glaucoma, Primary Open Angle"
      ],
      "interventions": [
        {
          "name": "NT-501 CNTF Implant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jeffrey L Goldberg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2011-04",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2016-08-02",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01408472"
    },
    {
      "nct_id": "NCT04405245",
      "title": "Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ocular Hypertension",
        "Primary Open Angle Glaucoma"
      ],
      "interventions": [
        {
          "name": "Latanoprost ophthalmic solution",
          "type": "DRUG"
        },
        {
          "name": "AKB-9778 4%",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "EyePoint Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 194,
      "start_date": "2020-06-06",
      "completion_date": "2020-11-05",
      "has_results": true,
      "last_update_posted_date": "2023-05-25",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 21,
      "location_summary": "Inglewood, California • Mission Hills, California • Newport Beach, California + 18 more",
      "locations": [
        {
          "city": "Inglewood",
          "state": "California"
        },
        {
          "city": "Mission Hills",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Petaluma",
          "state": "California"
        },
        {
          "city": "Largo",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04405245"
    },
    {
      "nct_id": "NCT02646488",
      "title": "Using Practice Facilitation in Primary Care Settings to Reduce Risk Factors for Cardiovascular Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "High Blood Pressure"
      ],
      "interventions": [
        {
          "name": "Million Hearts ABCS 6 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Million Hearts ABCS 9 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Million Hearts ABCS 12 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Million Hearts ABCS 15 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care Regimen 9 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care Regimen 12 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care Regimen 15 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care Regimen 18 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care Regimen 21 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care Regimen 24 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care Regimen 27 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Follow Up Post Intervention 21 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Follow Up Post Intervention 24 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Follow Up Post Intervention 27 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Follow Up Post Intervention 30 Months",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Follow Up Post Intervention 33 Months",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 276,
      "start_date": "2015-08",
      "completion_date": "2019-04-01",
      "has_results": false,
      "last_update_posted_date": "2019-05-20",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02646488"
    },
    {
      "nct_id": "NCT05017935",
      "title": "RADIANCE Continued Access Protocol",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Hypertension, Resistant to Conventional Therapy",
        "Vascular Diseases",
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Renal Denervation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ReCor Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 300,
      "start_date": "2022-05-04",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-06-17",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 40,
      "location_summary": "Chula Vista, California • Los Angeles, California • Sacramento, California + 34 more",
      "locations": [
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05017935"
    },
    {
      "nct_id": "NCT00902304",
      "title": "Valsartan Intensified Primary Care Reduction of Blood Pressure Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Valsartan and hydrochlorothiazide (HCTZ) - monotherapy",
          "type": "DRUG"
        },
        {
          "name": "Valsartan and amlodipine",
          "type": "DRUG"
        },
        {
          "name": "Usual care",
          "type": "DRUG"
        },
        {
          "name": "Valsartan",
          "type": "DRUG"
        },
        {
          "name": "Valsartan and hydrochlorothiazide (HCTZ) - combination arm",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2337,
      "start_date": "2009-07",
      "completion_date": "2011-07",
      "has_results": true,
      "last_update_posted_date": "2012-12-04",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 1,
      "location_summary": "East Hanover, New Jersey",
      "locations": [
        {
          "city": "East Hanover",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00902304"
    },
    {
      "nct_id": "NCT00824824",
      "title": "Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Dorzolamide 2%-timolol 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Brimonidine 0.2%-0.5% timolol 0.5",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts Eye and Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 21,
      "start_date": "2009-01",
      "completion_date": "2012-08",
      "has_results": true,
      "last_update_posted_date": "2017-04-04",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00824824"
    },
    {
      "nct_id": "NCT02599688",
      "title": "Open Label Extension of LipoLat-CS202",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Observation only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Peregrine Ophthalmic",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 18,
      "start_date": "2015-11",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2020-12-14",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 1,
      "location_summary": "Goose Creek, South Carolina",
      "locations": [
        {
          "city": "Goose Creek",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02599688"
    },
    {
      "nct_id": "NCT00722254",
      "title": "Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Myelofibrosis",
        "Primary Pulmonary Hypertension",
        "Secondary Myelofibrosis",
        "Pulmonary Arterial Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2006-06",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2016-03-21",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 2,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00722254"
    },
    {
      "nct_id": "NCT02023242",
      "title": "Comparing Effectiveness of the Hydrus Microstent (TM) to Two iStents to Lower IOP in Phakic Eyes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Open Angle Glaucoma",
        "Pseudoexfoliative Glaucoma",
        "Pigmentary Glaucoma"
      ],
      "interventions": [
        {
          "name": "Hydrus Microstent",
          "type": "DEVICE"
        },
        {
          "name": "iStent Trabecular Micro Bypass",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ivantis, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "45 Years to 84 Years"
      },
      "enrollment_count": 152,
      "start_date": "2012-10",
      "completion_date": "2018-01",
      "has_results": true,
      "last_update_posted_date": "2019-12-10",
      "last_synced_at": "2026-06-11T03:10:31.877Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02023242"
    }
  ]
}