{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Aphasia+in+Alzheimer%27s+Disease",
    "query": {
      "condition": "Progressive Aphasia in Alzheimer's Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Aphasia+in+Alzheimer%27s+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T02:10:06.232Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02289118",
      "title": "Tau Imaging in Young Onset Dementia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease, Early Onset",
        "Logopenic Progressive Aphasia",
        "Posterior Cortical Atrophy (PCA)"
      ],
      "interventions": [
        {
          "name": "[18F]-T807 imaging tracer",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "45 Years to 70 Years"
      },
      "enrollment_count": 16,
      "start_date": "2014-11",
      "completion_date": "2019-01-31",
      "has_results": false,
      "last_update_posted_date": "2020-03-25",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02289118"
    },
    {
      "nct_id": "NCT01465360",
      "title": "Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease",
        "Mild Cognitive Impairment",
        "Vascular Dementia",
        "Fronto-temporal Dementia",
        "Primary Progressive Aphasia",
        "Parkinson' Disease Dementia",
        "Mixed Dementia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Exonhit",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2011-11",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2012-07-06",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 3,
      "location_summary": "Las Vegas, Nevada • Cleveland, Ohio • Lakewood, Ohio",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Lakewood",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01465360"
    },
    {
      "nct_id": "NCT04122001",
      "title": "Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease, Early Onset",
        "Atypical Alzheimer's Disease",
        "Logopenic Progressive Aphasia"
      ],
      "interventions": [
        {
          "name": "Active, in-person HD-tDCS or active remote tDCS",
          "type": "DEVICE"
        },
        {
          "name": "Sham",
          "type": "DEVICE"
        },
        {
          "name": "Word List Learning Intervention (WordLLI)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "45 Years to 85 Years"
      },
      "enrollment_count": 90,
      "start_date": "2020-08-17",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04122001"
    },
    {
      "nct_id": "NCT06538311",
      "title": "Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Logopenic Progressive Aphasia",
        "Amnestic Symptoms"
      ],
      "interventions": [
        {
          "name": "Active rTMS",
          "type": "DEVICE"
        },
        {
          "name": "Sham rTMS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "40 Years to 99 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-05-01",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06538311"
    },
    {
      "nct_id": "NCT05741853",
      "title": "Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Progressive Aphasia",
        "Dementia",
        "Dementia, Frontotemporal",
        "Alzheimer Disease",
        "Neurodegenerative Diseases",
        "Frontotemporal Lobar Degeneration",
        "Apraxia, Motor",
        "Dysarthria",
        "Communication Disorders",
        "Language Disorders",
        "Speech Disorders",
        "Neurocognitive Disorders",
        "Aphasia",
        "Bilingual Aphasia"
      ],
      "interventions": [
        {
          "name": "Video-Implemented Script Training for Aphasia (VISTA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lexical Retrieval Training (LRT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stephanie Grasso",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-05-01",
      "completion_date": "2027-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05741853"
    },
    {
      "nct_id": "NCT03283449",
      "title": "Tau PET Imaging in Atypical Dementias",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Primary Progressive Aphasia With Suspected Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "18F-AV-1451",
          "type": "DRUG"
        },
        {
          "name": "PET",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "20 Years to 100 Years"
      },
      "enrollment_count": 70,
      "start_date": "2016-02",
      "completion_date": "2025-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03283449"
    },
    {
      "nct_id": "NCT02675270",
      "title": "Rehabilitation and Prophylaxis of Anomia in Primary Progressive Aphasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aphasia, Primary Progressive",
        "Anomia",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Phonological",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Orthographic",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Semantic",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lexical",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Untrained",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2011-11",
      "completion_date": "2024-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-09-25",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02675270"
    },
    {
      "nct_id": "NCT04720001",
      "title": "Florbetaben PET Imaging in PPA",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Progressive Aphasia",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Florbetaben F18",
          "type": "DRUG"
        },
        {
          "name": "PET",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 1,
      "start_date": "2018-08-23",
      "completion_date": "2021-02-26",
      "has_results": false,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04720001"
    },
    {
      "nct_id": "NCT07260253",
      "title": "Remotely-supervised Neuromodulation in PPA",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Progressive Aphasia(PPA)",
        "Progressive Aphasia",
        "Progressive Aphasia in Alzheimer's Disease",
        "Logopenic Progressive Aphasia (LPA)",
        "Logopenic Variant Primary Progressive Aphasia",
        "Logopenic Variant of Primary Progressive Aphasia (LPA)"
      ],
      "interventions": [
        {
          "name": "Lexical Retrieval Cascade Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remotely Supervised Transcranial Direct Current Stimulation- Active",
          "type": "DEVICE"
        },
        {
          "name": "Remotely Supervised Transcranial Direct Current Stimulation - Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Maya Henry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2026-04-15",
      "completion_date": "2029-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Austin, Texas",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07260253"
    },
    {
      "nct_id": "NCT01723553",
      "title": "Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Atypical Alzheimers Disease",
        "Logopenic Variant of Primary Progressive Aphasia (LPA)",
        "Posterior Cortical Atrophy (PCA)"
      ],
      "interventions": [
        {
          "name": "C-11 PiB",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2012-11",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2015-12-21",
      "last_synced_at": "2026-06-26T02:10:06.232Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01723553"
    }
  ]
}