{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Cognitive+Decline&page=13",
    "query": {
      "condition": "Progressive Cognitive Decline",
      "page": 13
    },
    "page_size": 10
  },
  "pagination": {
    "page": 13,
    "page_size": 10,
    "total_count": 346,
    "total_pages": 35,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Cognitive+Decline&page=14&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Cognitive+Decline&page=12&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-27T19:07:36.583Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00010920",
      "title": "Preventing Cognitive Decline With Alternative Therapies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dementia",
        "Memory Disorders"
      ],
      "interventions": [
        {
          "name": "Ginkgo Biloba Extract",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Center for Complementary and Integrative Health (NCCIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "85 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "85 Years and older"
      },
      "enrollment_count": null,
      "start_date": "1999-09",
      "completion_date": "2004-12",
      "has_results": false,
      "last_update_posted_date": "2006-08-18",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00010920"
    },
    {
      "nct_id": "NCT05256745",
      "title": "RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cancer Related Cognitive Decline",
        "Non-metastatic Breast Cancer"
      ],
      "interventions": [
        {
          "name": "TTP488",
          "type": "DRUG"
        },
        {
          "name": "ddAC/ddT",
          "type": "DRUG"
        },
        {
          "name": "TC",
          "type": "DRUG"
        },
        {
          "name": "TCHP",
          "type": "DRUG"
        },
        {
          "name": "Chemotherapy regimen that includes ddAC",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 48,
      "start_date": "2023-06-06",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Hackensack, New Jersey",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Hackensack",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05256745"
    },
    {
      "nct_id": "NCT06019195",
      "title": "The Effect of Intermittent Fasting on Brain Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intermittent Fasting",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Time restricted eating",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "55 Years to 80 Years"
      },
      "enrollment_count": 32,
      "start_date": "2024-05-13",
      "completion_date": "2026-02-02",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06019195"
    },
    {
      "nct_id": "NCT04058431",
      "title": "Osteopathic Manipulation Makes a Neuropsychological Difference",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Change",
        "Musculoskeletal Pain"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment",
          "type": "OTHER"
        },
        {
          "name": "Control- No Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Midwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2017-01",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-30",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Downers Grove, Illinois",
      "locations": [
        {
          "city": "Downers Grove",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04058431"
    },
    {
      "nct_id": "NCT04474379",
      "title": "Everyday Memory Impairment in PD-related Cognitive Decline",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Strategy Training (Time- and Event- Based)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2021-11-29",
      "completion_date": "2026-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04474379"
    },
    {
      "nct_id": "NCT07856043",
      "title": "[11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Failure With Reduced Ejection Fraction",
        "Cognitive Impairment, Mild",
        "Neuroinflammation",
        "Vascular Contributions to Cognitive Impairment and Dementia (VCID)"
      ],
      "interventions": [
        {
          "name": "[11C]PS13: [carbon-11]PS13; COX-1 PET radioligand",
          "type": "DRUG"
        },
        {
          "name": "Sacubitril-Valsartan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 18,
      "start_date": "2026-10-01",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-02",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07856043"
    },
    {
      "nct_id": "NCT05994391",
      "title": "A Prospective, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of LasoperinTM on Cognitive Function in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Impairment",
        "Cognitive Decline",
        "Cognition Disorders in Old Age",
        "Well-Being, Psychological",
        "Inflammation",
        "Cognitive Fun"
      ],
      "interventions": [
        {
          "name": "LasoperinTM",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placeo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Lindenwood University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Years to 60 Years"
      },
      "enrollment_count": 100,
      "start_date": "2022-06-03",
      "completion_date": "2022-10-18",
      "has_results": false,
      "last_update_posted_date": "2023-08-16",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Saint Charles, Missouri",
      "locations": [
        {
          "city": "Saint Charles",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05994391"
    },
    {
      "nct_id": "NCT05414682",
      "title": "Brain Healthy Soul Food Diet Intervention Among Older African Americans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "MIND+SOUL Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2022-08-01",
      "completion_date": "2023-11-01",
      "has_results": true,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05414682"
    },
    {
      "nct_id": "NCT03743792",
      "title": "Acute Raspberry Intake on Metabolic Control and Cognitive Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Age-related Cognitive Decline",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Active breakfast",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Control breakfast",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "USDA Human Nutrition Research Center on Aging",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "55 Years to 70 Years"
      },
      "enrollment_count": 6,
      "start_date": "2019-02-01",
      "completion_date": "2023-04-30",
      "has_results": false,
      "last_update_posted_date": "2023-05-10",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03743792"
    },
    {
      "nct_id": "NCT03926702",
      "title": "Tau Imaging With JNJ067",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Progressive Supranuclear Palsy"
      ],
      "interventions": [
        {
          "name": "Radiopharmaceuticals",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Berkeley",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2019-06-18",
      "completion_date": "2021-01-06",
      "has_results": false,
      "last_update_posted_date": "2022-08-31",
      "last_synced_at": "2026-10-27T19:07:36.583Z",
      "location_count": 1,
      "location_summary": "Berkeley, California",
      "locations": [
        {
          "city": "Berkeley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03926702"
    }
  ]
}